3L76
Crystal Structure of Aspartate Kinase from Synechocystis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004072 | molecular_function | aspartate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0009090 | biological_process | homoserine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| B | 0004072 | molecular_function | aspartate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0009090 | biological_process | homoserine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE THR A 601 |
| Chain | Residue |
| A | ASP280 |
| A | HOH630 |
| A | HOH631 |
| A | ARG281 |
| A | PRO282 |
| A | GLY283 |
| A | VAL284 |
| A | ALA285 |
| A | GLN304 |
| A | ASN557 |
| A | ILE558 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE THR A 602 |
| Chain | Residue |
| A | ASN385 |
| A | ILE386 |
| A | ASP454 |
| A | ARG455 |
| A | GLY457 |
| A | MET458 |
| A | ALA459 |
| A | GLN478 |
| A | HOH613 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE LYS A 603 |
| Chain | Residue |
| A | ASP298 |
| A | ILE299 |
| A | ASP300 |
| A | MET537 |
| A | HIS540 |
| A | GLY542 |
| A | VAL543 |
| A | ALA544 |
| A | THR563 |
| A | SER564 |
| A | ILE568 |
| A | HOH614 |
| A | HOH674 |
| A | HOH691 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE LYS A 604 |
| Chain | Residue |
| A | MET365 |
| A | ARG368 |
| A | GLY370 |
| A | ILE371 |
| A | ALA372 |
| A | SER392 |
| A | GLU393 |
| A | SER472 |
| A | VAL473 |
| A | ASP474 |
| A | HOH607 |
| A | HOH609 |
| A | HOH624 |
| A | HOH687 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 605 |
| Chain | Residue |
| A | ARG277 |
| A | ARG277 |
| A | ASP308 |
| A | ASP308 |
| A | ASN310 |
| A | ASN310 |
| A | SER311 |
| A | SER311 |
| A | ARG483 |
| A | ARG483 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE THR B 601 |
| Chain | Residue |
| B | ASN385 |
| B | ILE386 |
| B | VAL452 |
| B | ASP454 |
| B | ARG455 |
| B | MET458 |
| B | ALA459 |
| B | GLN478 |
| B | ILE493 |
| B | HOH617 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE THR B 602 |
| Chain | Residue |
| B | ASP280 |
| B | ARG281 |
| B | PRO282 |
| B | GLY283 |
| B | VAL284 |
| B | ALA285 |
| B | GLN304 |
| B | ASN557 |
| B | ILE558 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE LYS B 603 |
| Chain | Residue |
| B | ASP298 |
| B | ILE299 |
| B | ASP300 |
| B | MET537 |
| B | HIS540 |
| B | PRO541 |
| B | GLY542 |
| B | VAL543 |
| B | ALA544 |
| B | THR563 |
| B | SER564 |
| B | ILE568 |
| B | HOH623 |
| B | HOH649 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE LYS B 604 |
| Chain | Residue |
| B | SER472 |
| B | VAL473 |
| B | ASP474 |
| B | HOH611 |
| B | HOH651 |
| B | MET365 |
| B | ARG368 |
| B | PRO369 |
| B | GLY370 |
| B | ILE371 |
| B | ALA372 |
| B | SER392 |
| B | GLU393 |
Functional Information from PROSITE/UniProt
| site_id | PS00324 |
| Number of Residues | 9 |
| Details | ASPARTOKINASE Aspartokinase signature. VqKFGGTSV |
| Chain | Residue | Details |
| A | VAL5-VAL13 |
