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3L50

The crystal structure of human Glia Maturation Factor, Gamma (GMFG)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003779molecular_functionactin binding
A0004860molecular_functionprotein kinase inhibitor activity
A0005576cellular_componentextracellular region
A0006468biological_processprotein phosphorylation
A0007165biological_processsignal transduction
A0008047molecular_functionenzyme activator activity
A0008083molecular_functiongrowth factor activity
A0030864cellular_componentcortical actin cytoskeleton
A0034316biological_processnegative regulation of Arp2/3 complex-mediated actin nucleation
A0034774cellular_componentsecretory granule lumen
A0071846biological_processactin filament debranching
A0071933molecular_functionArp2/3 complex binding
A1904813cellular_componentficolin-1-rich granule lumen
B0003779molecular_functionactin binding
B0004860molecular_functionprotein kinase inhibitor activity
B0005576cellular_componentextracellular region
B0006468biological_processprotein phosphorylation
B0007165biological_processsignal transduction
B0008047molecular_functionenzyme activator activity
B0008083molecular_functiongrowth factor activity
B0030864cellular_componentcortical actin cytoskeleton
B0034316biological_processnegative regulation of Arp2/3 complex-mediated actin nucleation
B0034774cellular_componentsecretory granule lumen
B0071846biological_processactin filament debranching
B0071933molecular_functionArp2/3 complex binding
B1904813cellular_componentficolin-1-rich granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL B 1
ChainResidue
BLYS108
BLYS108
BASN109
BASN109

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL B 2
ChainResidue
BVAL120
BGLU122
BLYS137

225946

PDB entries from 2024-10-09

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