3L0S

Crystal structures of Zinc, Cobalt and Iron containing Adenylate kinase from Gram-negative bacteria Desulfovibrio gigas

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004017	molecular_function	adenylate kinase activity
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0009123	biological_process	nucleoside monophosphate metabolic process
A	0009132	biological_process	nucleoside diphosphate metabolic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0016301	molecular_function	kinase activity
A	0019205	molecular_function	nucleobase-containing compound kinase activity
A	0044209	biological_process	AMP salvage
A	0046872	molecular_function	metal ion binding
A	0046940	biological_process	nucleoside monophosphate phosphorylation
A	0050145	molecular_function	nucleoside monophosphate kinase activity
C	0004017	molecular_function	adenylate kinase activity
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0009123	biological_process	nucleoside monophosphate metabolic process
C	0009132	biological_process	nucleoside diphosphate metabolic process
C	0009165	biological_process	nucleotide biosynthetic process
C	0016301	molecular_function	kinase activity
C	0019205	molecular_function	nucleobase-containing compound kinase activity
C	0044209	biological_process	AMP salvage
C	0046872	molecular_function	metal ion binding
C	0046940	biological_process	nucleoside monophosphate phosphorylation
C	0050145	molecular_function	nucleoside monophosphate kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO A 224

Chain	Residue
A	CYS129
A	HIS135
A	CYS151
A	CYS154

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site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TAR A 225

Chain	Residue
A	LYS13
A	ARG126
A	HOH417
A	HOH440
A	HOH482
A	HOH499
C	ASN131
C	ASN132
C	HOH243
A	PRO8
A	ASN9
A	GLY10
A	SER11
A	GLY12

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO C 224

Chain	Residue
C	CYS129
C	HIS135
C	CYS151
C	CYS154

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site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE TAR C 225

Chain	Residue
A	ASN131
A	ASN132
C	PRO8
C	ASN9
C	GLY10
C	SER11
C	GLY12
C	LYS13
C	GLY14
C	ARG126
C	HOH293
C	HOH308
C	HOH416
C	HOH428

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Functional Information from PROSITE/UniProt

site_id	PS00113
Number of Residues	12
Details	ADENYLATE_KINASE Adenylate kinase signature. WLLDGFPRntvQ

Chain	Residue	Details
A	TRP80-GLN91

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