3KZU
Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 421 |
| Chain | Residue |
| B | ARG74 |
| B | SER137 |
| B | PRO138 |
| B | ARG383 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 422 |
| Chain | Residue |
| B | HOH1057 |
| B | LYS71 |
| B | LYS75 |
| B | ARG383 |
| B | HOH507 |
| B | HOH647 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 421 |
| Chain | Residue |
| C | THR58 |
| C | ASN59 |
| C | TYR418 |
| C | THR419 |
| C | ALA420 |
| C | HOH596 |
| C | HOH1137 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 422 |
| Chain | Residue |
| C | GLY18 |
| C | VAL19 |
| C | GLU20 |
| C | GLU21 |
| C | HOH451 |
| C | HOH619 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 421 |
| Chain | Residue |
| A | PRO138 |
| A | HOH927 |
| B | THR278 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 422 |
| Chain | Residue |
| A | ILE277 |
| A | THR278 |
| B | PRO138 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGYGMSGDAFhItaptesgegaqrcmv...AALK |
| Chain | Residue | Details |
| A | ILE266-LYS296 |
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GPNhsVVtACATGthAI |
| Chain | Residue | Details |
| A | GLY161-ILE177 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| A | PHE406 | |
| A | HIS311 | |
| A | HIS347 | |
| A | CYS170 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| B | PHE406 | |
| B | HIS311 | |
| B | HIS347 | |
| B | CYS170 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| C | PHE406 | |
| C | HIS311 | |
| C | HIS347 | |
| C | CYS170 |
| site_id | CSA4 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| A | PHE406 | |
| A | LYS342 | |
| A | HIS311 | |
| A | CYS170 | |
| A | HIS347 | |
| A | PHE404 |
| site_id | CSA5 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| B | PHE406 | |
| B | LYS342 | |
| B | HIS311 | |
| B | CYS170 | |
| B | HIS347 | |
| B | PHE404 |
| site_id | CSA6 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1kas |
| Chain | Residue | Details |
| C | PHE406 | |
| C | LYS342 | |
| C | HIS311 | |
| C | CYS170 | |
| C | HIS347 | |
| C | PHE404 |
