Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3KX9

Engineering a closed form of the Archaeoglobus fulgidus ferritin by site directed mutagenesis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004322	molecular_function	ferroxidase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0004322	molecular_function	ferroxidase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0004322	molecular_function	ferroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0004322	molecular_function	ferroxidase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0016491	molecular_function	oxidoreductase activity
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
F	0004322	molecular_function	ferroxidase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0016491	molecular_function	oxidoreductase activity
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
G	0004322	molecular_function	ferroxidase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0016491	molecular_function	oxidoreductase activity
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
H	0004322	molecular_function	ferroxidase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0016491	molecular_function	oxidoreductase activity
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
I	0004322	molecular_function	ferroxidase activity
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0016491	molecular_function	oxidoreductase activity
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
J	0004322	molecular_function	ferroxidase activity
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0016491	molecular_function	oxidoreductase activity
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
K	0004322	molecular_function	ferroxidase activity
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0016491	molecular_function	oxidoreductase activity
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
L	0004322	molecular_function	ferroxidase activity
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0016491	molecular_function	oxidoreductase activity
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
M	0004322	molecular_function	ferroxidase activity
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0016491	molecular_function	oxidoreductase activity
M	0042802	molecular_function	identical protein binding
M	0046872	molecular_function	metal ion binding
N	0004322	molecular_function	ferroxidase activity
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0016491	molecular_function	oxidoreductase activity
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
O	0004322	molecular_function	ferroxidase activity
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0016491	molecular_function	oxidoreductase activity
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
P	0004322	molecular_function	ferroxidase activity
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0016491	molecular_function	oxidoreductase activity
P	0042802	molecular_function	identical protein binding
P	0046872	molecular_function	metal ion binding
Q	0004322	molecular_function	ferroxidase activity
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0042802	molecular_function	identical protein binding
Q	0046872	molecular_function	metal ion binding
R	0004322	molecular_function	ferroxidase activity
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0016491	molecular_function	oxidoreductase activity
R	0042802	molecular_function	identical protein binding
R	0046872	molecular_function	metal ion binding
S	0004322	molecular_function	ferroxidase activity
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0016491	molecular_function	oxidoreductase activity
S	0042802	molecular_function	identical protein binding
S	0046872	molecular_function	metal ion binding
T	0004322	molecular_function	ferroxidase activity
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0016491	molecular_function	oxidoreductase activity
T	0042802	molecular_function	identical protein binding
T	0046872	molecular_function	metal ion binding
U	0004322	molecular_function	ferroxidase activity
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0008198	molecular_function	ferrous iron binding
U	0008199	molecular_function	ferric iron binding
U	0016491	molecular_function	oxidoreductase activity
U	0042802	molecular_function	identical protein binding
U	0046872	molecular_function	metal ion binding
V	0004322	molecular_function	ferroxidase activity
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0016491	molecular_function	oxidoreductase activity
V	0042802	molecular_function	identical protein binding
V	0046872	molecular_function	metal ion binding
W	0004322	molecular_function	ferroxidase activity
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0016491	molecular_function	oxidoreductase activity
W	0042802	molecular_function	identical protein binding
W	0046872	molecular_function	metal ion binding
X	0004322	molecular_function	ferroxidase activity
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0016491	molecular_function	oxidoreductase activity
X	0042802	molecular_function	identical protein binding
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 174

Chain	Residue
A	HIS95
A	ASN98
A	HOH1097

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 174

Chain	Residue
B	HIS95
B	ASN98
B	ARG102
B	HOH995

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 174

Chain	Residue
C	ARG102
C	HOH493
C	HOH1115
C	HIS95
C	ASN98

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 174

Chain	Residue
D	TYR21
D	HIS95
D	ASN98
D	HOH1112

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL E 174

Chain	Residue
E	HIS95
E	ASN98
E	ARG102
E	HOH809
E	HOH1100

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL F 174

Chain	Residue
F	HIS95
F	ASN98

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL G 174

Chain	Residue
G	HIS95
G	ASN98

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL H 174

Chain	Residue
H	HIS95
H	ASN98
H	HOH357
H	HOH362

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL I 174

Chain	Residue
I	GLU94
I	HIS95
I	ASN98
I	ARG102
I	HOH953
I	HOH1091

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL J 174

Chain	Residue
J	TYR21
J	HIS95
J	ASN98
J	ARG102

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL K 174

Chain	Residue
K	HIS95
K	ASN98
K	HOH1104

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL L 174

Chain	Residue
L	HIS95
L	ASN98
L	ARG102
L	HOH395
L	HOH585

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL M 174

Chain	Residue
M	HIS95
M	ASN98
M	HOH486
M	HOH506

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL N 174

Chain	Residue
N	HIS95
N	ASN98
N	ARG102
N	HOH1094
N	HOH1116

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL O 174

Chain	Residue
O	HIS95
O	ASN98
O	HOH1099

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL P 174

Chain	Residue
P	HIS95
P	ASN98
P	ARG102
P	HOH457

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL Q 174

Chain	Residue
Q	TYR21
Q	HIS95
Q	ASN98
Q	ARG102
Q	HOH708

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL R 174

Chain	Residue
N	HOH985
R	TYR21
R	HIS95
R	ASN98

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL S 174

Chain	Residue
S	TYR21
S	HIS95
S	ASN98
S	ARG102

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL T 174

Chain	Residue
T	TYR21
T	HIS95
T	ASN98

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL U 174

Chain	Residue
U	TYR21
U	HIS95
U	ASN98
U	ARG102
U	HOH1090

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL V 174

Chain	Residue
V	TYR21
V	HIS95
V	ASN98

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL W 174

Chain	Residue
W	HIS95
W	ASN98
W	ARG102
W	HOH1113

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL X 174

Chain	Residue
X	TYR21
X	HIS95
X	ASN98
X	HOH618

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)