3KWM
Crystal structure of ribose-5-isomerase A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006014 | biological_process | D-ribose metabolic process |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0044281 | biological_process | small molecule metabolic process |
| B | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006014 | biological_process | D-ribose metabolic process |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0044281 | biological_process | small molecule metabolic process |
| C | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006014 | biological_process | D-ribose metabolic process |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0044281 | biological_process | small molecule metabolic process |
| D | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006014 | biological_process | D-ribose metabolic process |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0044281 | biological_process | small molecule metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 225 |
| Chain | Residue |
| A | VAL198 |
| A | VAL199 |
| A | HOH241 |
| D | VAL198 |
| D | VAL199 |
| D | HOH234 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 226 |
| Chain | Residue |
| A | HOH240 |
| A | HOH260 |
| A | HOH261 |
| A | SER36 |
| A | THR37 |
| A | LYS127 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 225 |
| Chain | Residue |
| B | VAL198 |
| B | VAL199 |
| C | VAL198 |
| C | VAL199 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 226 |
| Chain | Residue |
| B | LYS13 |
| B | SER36 |
| B | THR37 |
| B | LYS127 |
| B | HOH254 |
| B | HOH287 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG C 225 |
| Chain | Residue |
| C | GLN165 |
| C | ILE167 |
| C | ASP169 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 226 |
| Chain | Residue |
| C | GLY39 |
| C | GLU43 |
| C | LYS65 |
| C | HOH277 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG C 227 |
| Chain | Residue |
| C | TYR162 |
| C | HOH242 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG C 228 |
| Chain | Residue |
| C | ASN134 |
| C | GLN159 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 3GR D 225 |
| Chain | Residue |
| D | GLY35 |
| D | ALA89 |
| D | ASP90 |
| D | LYS100 |
| D | GLY101 |
| D | GLY102 |
| D | GLY103 |
| D | PO4226 |
| D | HOH277 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 226 |
| Chain | Residue |
| D | LYS13 |
| D | SER36 |
| D | THR37 |
| D | ALA89 |
| D | LYS127 |
| D | 3GR225 |
| D | HOH289 |
| D | HOH300 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00170","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00170","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of ribose-5-isomerase A.","authoringGroup":["Center for Structural Genomics of Infectious Diseases (CSGID)"],"authors":["Orlikowska M.","Rostankowski R.","Nakka C.","Hattne J.","Grimshaw S.","Borek D.","Otwinowski Z."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2013","submissionDatabase":"PDB data bank","title":"Structural and biophysical studies of Ribose-5-Phosphate Isomerase A from Francisella tularensis.","authoringGroup":["Center for Structural Genomics of Infectious Diseases (CSGID)"],"authors":["Rostankowski R.","Orlikowska M.","Nakka C.","Grimshaw S.","Borek D.","Otwinowski Z."]}}]} |
| Chain | Residue | Details |
