Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009236 | biological_process | cobalamin biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 400 |
| Chain | Residue |
| A | ARG94 |
| A | ASN100 |
| A | ARG203 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 300 |
| Chain | Residue |
| A | ARG219 |
| A | EDO303 |
| A | PRO199 |
| A | ASP200 |
| A | CYS202 |
| A | ASP214 |
| A | LYS215 |
| A | ASP216 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 301 |
| Chain | Residue |
| A | LEU19 |
| A | LYS83 |
| A | ILE84 |
| A | THR85 |
| A | HIS184 |
| A | HOH244 |
| A | EDO309 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| A | GLU90 |
| A | TYR121 |
| A | ASP129 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 303 |
| Chain | Residue |
| A | VAL92 |
| A | ASP175 |
| A | THR201 |
| A | ARG203 |
| A | EDO300 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | LYS211 |
| A | LEU213 |
| A | ASN224 |
| A | GLU227 |
| A | GLY228 |
| A | GLU231 |
| A | HOH291 |
| A | HOH338 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 305 |
| Chain | Residue |
| A | GLU23 |
| A | ILE43 |
| A | ILE71 |
| A | HOH315 |
| A | HOH335 |
| A | HOH388 |
| A | HOH402 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 306 |
| Chain | Residue |
| A | ASN20 |
| A | LEU22 |
| A | ASN185 |
| A | ASN224 |
| A | GLU227 |
| A | HOH319 |
| A | HOH335 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 307 |
| Chain | Residue |
| A | HIS27 |
| A | LYS29 |
| A | ASP30 |
| A | ILE62 |
| A | ARG77 |
| A | HOH332 |
| A | HOH426 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 308 |
| Chain | Residue |
| A | SER115 |
| A | PRO116 |
| A | GLY135 |
| A | LEU138 |
| A | SER139 |
| A | HOH391 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 309 |
| Chain | Residue |
| A | LEU19 |
| A | HIS184 |
| A | ASN185 |
| A | EDO301 |
| A | HOH314 |
Functional Information from PROSITE/UniProt
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LVDfKLEFG |
| Chain | Residue | Details |
| A | LEU173-GLY181 | |
