3KR6
MurA dead-end complex with fosfomycin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0008760 | molecular_function | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019277 | biological_process | UDP-N-acetylgalactosamine biosynthetic process |
| A | 0051301 | biological_process | cell division |
| A | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FFQ A 500 |
| Chain | Residue |
| A | LYS22 |
| A | ARG91 |
| A | GLY114 |
| A | CYS115 |
| A | ARG120 |
| A | ARG397 |
| A | HOH446 |
| A | UD1450 |
| A | HOH496 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE UD1 A 450 |
| Chain | Residue |
| A | ASN23 |
| A | ARG91 |
| A | TRP95 |
| A | ARG120 |
| A | PRO121 |
| A | VAL122 |
| A | ASP123 |
| A | LEU124 |
| A | HIS125 |
| A | LYS160 |
| A | SER162 |
| A | VAL163 |
| A | GLY164 |
| A | THR304 |
| A | ASP305 |
| A | VAL327 |
| A | PHE328 |
| A | ARG331 |
| A | HOH451 |
| A | HOH455 |
| A | HOH468 |
| A | HOH472 |
| A | HOH476 |
| A | HOH480 |
| A | HOH484 |
| A | FFQ500 |
| A | HOH509 |
| A | HOH554 |
| A | HOH591 |
| A | HOH598 |
| A | HOH794 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:8994972, ECO:0000305|PubMed:22378791, ECO:0007744|PDB:1UAE, ECO:0007744|PDB:3KR6 |
| Chain | Residue | Details |
| A | CYS115 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:20392080, ECO:0000305|PubMed:22378791, ECO:0007744|PDB:3KR6, ECO:0007744|PDB:3SWD |
| Chain | Residue | Details |
| A | LYS22 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20392080, ECO:0007744|PDB:3KR6 |
| Chain | Residue | Details |
| A | ARG91 | |
| A | VAL327 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:22378791, ECO:0007744|PDB:3KR6 |
| Chain | Residue | Details |
| A | ARG120 | |
| A | LYS160 | |
| A | ASP305 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000305|PubMed:22378791 |
| Chain | Residue | Details |
| A | CYS115 |
