3KQ4

Structure of Intrinsic Factor-Cobalamin bound to its receptor Cubilin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005768	cellular_component	endosome
A	0005902	cellular_component	microvillus
A	0006824	biological_process	cobalt ion transport
A	0015889	biological_process	cobalamin transport
A	0016324	cellular_component	apical plasma membrane
A	0031419	molecular_function	cobalamin binding
A	0043202	cellular_component	lysosomal lumen
A	0140355	molecular_function	cargo receptor ligand activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005768	cellular_component	endosome
C	0005902	cellular_component	microvillus
C	0006824	biological_process	cobalt ion transport
C	0015889	biological_process	cobalamin transport
C	0016324	cellular_component	apical plasma membrane
C	0031419	molecular_function	cobalamin binding
C	0043202	cellular_component	lysosomal lumen
C	0140355	molecular_function	cargo receptor ligand activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005768	cellular_component	endosome
E	0005902	cellular_component	microvillus
E	0006824	biological_process	cobalt ion transport
E	0015889	biological_process	cobalamin transport
E	0016324	cellular_component	apical plasma membrane
E	0031419	molecular_function	cobalamin binding
E	0043202	cellular_component	lysosomal lumen
E	0140355	molecular_function	cargo receptor ligand activity

Functional Information from PROSITE/UniProt

site_id	PS00468
Number of Residues	14
Details	COBALAMIN_BINDING Eukaryotic cobalamin-binding proteins signature. NVDTGAMAtLALTC

Chain	Residue	Details
A	ASN169-CYS182

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	57
Details	BINDING: BINDING => ECO:0000305\|PubMed:20237569, ECO:0007744\|PDB:3KQ4

site_id	SWS_FT_FI2
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

site_id	SWS_FT_FI3
Number of Residues	24
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:20237569, ECO:0007744\|PDB:3KQ4

site_id	SWS_FT_FI4
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:20237569

site_id	SWS_FT_FI5
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

site_id	SWS_FT_FI6
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:17954916, ECO:0000269\|PubMed:20237569