3KNF

Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA deacylase activity
A	0003723	molecular_function	RNA binding
A	0005737	cellular_component	cytoplasm
A	0006399	biological_process	tRNA metabolic process
A	0016787	molecular_function	hydrolase activity
A	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
A	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
A	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0002161	molecular_function	aminoacyl-tRNA deacylase activity
B	0003723	molecular_function	RNA binding
B	0005737	cellular_component	cytoplasm
B	0006399	biological_process	tRNA metabolic process
B	0016787	molecular_function	hydrolase activity
B	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
B	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
B	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
B	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0002161	molecular_function	aminoacyl-tRNA deacylase activity
C	0003723	molecular_function	RNA binding
C	0005737	cellular_component	cytoplasm
C	0006399	biological_process	tRNA metabolic process
C	0016787	molecular_function	hydrolase activity
C	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
C	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
C	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
C	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
D	0000049	molecular_function	tRNA binding
D	0000166	molecular_function	nucleotide binding
D	0002161	molecular_function	aminoacyl-tRNA deacylase activity
D	0003723	molecular_function	RNA binding
D	0005737	cellular_component	cytoplasm
D	0006399	biological_process	tRNA metabolic process
D	0016787	molecular_function	hydrolase activity
D	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
D	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
D	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
D	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
E	0000049	molecular_function	tRNA binding
E	0000166	molecular_function	nucleotide binding
E	0002161	molecular_function	aminoacyl-tRNA deacylase activity
E	0003723	molecular_function	RNA binding
E	0005737	cellular_component	cytoplasm
E	0006399	biological_process	tRNA metabolic process
E	0016787	molecular_function	hydrolase activity
E	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
E	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
E	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
E	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
F	0000049	molecular_function	tRNA binding
F	0000166	molecular_function	nucleotide binding
F	0002161	molecular_function	aminoacyl-tRNA deacylase activity
F	0003723	molecular_function	RNA binding
F	0005737	cellular_component	cytoplasm
F	0006399	biological_process	tRNA metabolic process
F	0016787	molecular_function	hydrolase activity
F	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
F	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
F	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
F	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Motif: {"description":"C-terminal adenosine nucleotide of tRNA","evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"Gly-cisPro motif, allows the protein to recognize chirality of D-amino acids","evidences":[{"source":"PubMed","id":"24302572","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20007323","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KO4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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