3KND

TPX2:importin-alpha complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006606	biological_process	protein import into nucleus
A	0061608	molecular_function	nuclear import signal receptor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1

Chain	Residue
A	HOH22
A	LYS202
A	GLN352
A	LYS388
A	HOH557
A	HOH586
A	HOH601
A	HOH677

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 2

Chain	Residue
A	LYS348
A	THR349
A	HOH681
A	HOH693
A	PRO347

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 3

Chain	Residue
A	GLN371
A	VAL374
A	GLU411

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 4

Chain	Residue
A	HOH18
A	HOH48
A	GLY193
A	SER194
A	ALA195
A	SER342
A	HOH622

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 5

Chain	Residue
A	THR409
A	VAL410
A	HOH633
A	HOH637

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Repeat: {"description":"ARM 1; truncated"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	39
Details	Repeat: {"description":"ARM 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	41
Details	Repeat: {"description":"ARM 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	44
Details	Repeat: {"description":"ARM 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	36
Details	Repeat: {"description":"ARM 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	39
Details	Repeat: {"description":"ARM 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	39
Details	Repeat: {"description":"ARM 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	42
Details	Repeat: {"description":"ARM 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	46
Details	Repeat: {"description":"ARM 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	39
Details	Repeat: {"description":"ARM 10; atypical"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	96
Details	Region: {"description":"NLS binding site (major)","evidences":[{"source":"PubMed","id":"10764582","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	88
Details	Region: {"description":"NLS binding site (minor)","evidences":[{"source":"PubMed","id":"10764582","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---