3KLE

Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003964	molecular_function	RNA-directed DNA polymerase activity
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
A	0006278	biological_process	RNA-templated DNA biosynthetic process
B	0003964	molecular_function	RNA-directed DNA polymerase activity
B	0006278	biological_process	RNA-templated DNA biosynthetic process
E	0003676	molecular_function	nucleic acid binding
E	0003964	molecular_function	RNA-directed DNA polymerase activity
E	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
E	0006278	biological_process	RNA-templated DNA biosynthetic process
F	0003964	molecular_function	RNA-directed DNA polymerase activity
F	0006278	biological_process	RNA-templated DNA biosynthetic process
I	0003676	molecular_function	nucleic acid binding
I	0003964	molecular_function	RNA-directed DNA polymerase activity
I	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
I	0006278	biological_process	RNA-templated DNA biosynthetic process
J	0003964	molecular_function	RNA-directed DNA polymerase activity
J	0006278	biological_process	RNA-templated DNA biosynthetic process
M	0003676	molecular_function	nucleic acid binding
M	0003964	molecular_function	RNA-directed DNA polymerase activity
M	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
M	0006278	biological_process	RNA-templated DNA biosynthetic process
N	0003964	molecular_function	RNA-directed DNA polymerase activity
N	0006278	biological_process	RNA-templated DNA biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	8
Details	SITE: Essential for RT p66/p51 heterodimerization

site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Essential for RT p66/p51 heterodimerization

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Cleavage; by viral protease; partial

site_id	SWS_FT_FI5
Number of Residues	4
Details	SITE: Cleavage; by viral protease => ECO:0000250