Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE B95 A 216 |
| Chain | Residue |
| A | GLY23 |
| A | LEU160 |
| A | ASP161 |
| A | HIS162 |
| A | GLY163 |
| A | Z22217 |
| A | HOH531 |
| A | CYS25 |
| A | TRP26 |
| A | GLY65 |
| A | GLY66 |
| A | LEU67 |
| A | MET68 |
| A | ALA138 |
| A | GLN159 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 401 |
| Chain | Residue |
| A | ARG8 |
| A | VAL13 |
| A | THR14 |
| A | TYR193 |
| A | HOH232 |
| A | HOH297 |
| A | HOH505 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 402 |
| Chain | Residue |
| A | THR186 |
| A | GLN187 |
| A | TRP188 |
| A | GLY189 |
| A | GLU191 |
| A | HOH319 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | ASP121 |
| A | GLU122 |
| A | ASN201 |
| A | LYS206 |
| A | HOH229 |
| A | EDO407 |
| A | HOH519 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | LYS17 |
| A | ASP18 |
| A | GLU86 |
| A | TYR91 |
| A | HOH225 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 405 |
| Chain | Residue |
| A | ASN79 |
| A | ASN80 |
| A | ASN80 |
| A | ALA82 |
| A | TYR84 |
| A | HOH422 |
| A | HOH422 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 406 |
| Chain | Residue |
| A | THR59 |
| A | ASN70 |
| A | TRP74 |
| A | GLN77 |
| A | HOH353 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 407 |
| Chain | Residue |
| A | GLU122 |
| A | LYS198 |
| A | GLY199 |
| A | HOH229 |
| A | HOH340 |
| A | EDO403 |
| A | HOH489 |
| A | HOH518 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 408 |
| Chain | Residue |
| A | TRP128 |
| A | ASN132 |
| A | HOH428 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 409 |
| Chain | Residue |
| A | HIS43 |
| A | PRO44 |
| A | THR85 |
| A | THR107 |
| A | HOH421 |
| A | HOH447 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 410 |
| Chain | Residue |
| A | THR14 |
| A | ALA15 |
| A | LYS17 |
| A | LEU45 |
| A | ASN47 |
| A | HOH429 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE Z22 A 217 |
| Chain | Residue |
| A | GLN19 |
| A | CYS25 |
| A | HIS162 |
| A | B95216 |
| A | HOH273 |
| A | HOH341 |
| A | HOH342 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGqCGSCWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LDHGVLLVGYN |
| Chain | Residue | Details |
| A | LEU160-ASN170 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIiKNSWttqWGeeGYIrI |
| Chain | Residue | Details |
| A | TYR177-ILE196 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | CYS25 | |
| A | HIS162 | |
| A | ASN182 | |
| Chain | Residue | Details |
| A | GLY215 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN47 | |
| A | ASN170 | |
