3KI8
Crystal structure of hyperthermophilic nitrilase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000257 | molecular_function | nitrilase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| B | 0000257 | molecular_function | nitrilase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 3001 |
| Chain | Residue |
| A | CSD146 |
| A | TRP149 |
| A | LEU172 |
| A | VAL173 |
| A | MET174 |
| A | HOH289 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY A 3004 |
| Chain | Residue |
| A | ARG132 |
| A | VAL133 |
| A | HOH314 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 263 |
| Chain | Residue |
| A | HOH372 |
| A | HOH380 |
| A | HOH428 |
| A | HOH429 |
| A | HOH430 |
| A | HOH431 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY B 3002 |
| Chain | Residue |
| B | CSD146 |
| B | TRP149 |
| B | LEU172 |
| B | VAL173 |
| B | MET174 |
| B | HOH267 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 3003 |
| Chain | Residue |
| B | TYR118 |
| B | LEU204 |
| B | HOH289 |
| B | HOH322 |
| B | HOH398 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 263 |
| Chain | Residue |
| B | ASN49 |
| B | HOH264 |
| B | HOH322 |
| B | HOH323 |
| B | HOH324 |
| B | HOH398 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21095228","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"21095228","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21095228","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
