3KHP
Crystal structure of a possible dehydrogenase from Mycobacterium tuberculosis at 2.3A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006635 | biological_process | fatty acid beta-oxidation |
| A | 0016829 | molecular_function | lyase activity |
| A | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006635 | biological_process | fatty acid beta-oxidation |
| B | 0016829 | molecular_function | lyase activity |
| B | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006635 | biological_process | fatty acid beta-oxidation |
| C | 0016829 | molecular_function | lyase activity |
| C | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0006631 | biological_process | fatty acid metabolic process |
| D | 0006635 | biological_process | fatty acid beta-oxidation |
| D | 0016829 | molecular_function | lyase activity |
| D | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | LEU183 |
| A | GLY185 |
| A | ARG187 |
| A | HOH389 |
| C | ARG22 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | GLY34 |
| A | GLY36 |
| D | GLN199 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE TLA B 300 |
| Chain | Residue |
| B | ALA77 |
| B | ASP186 |
| B | ASN188 |
| B | HIS191 |
| B | HIS209 |
| B | GLY210 |
| B | LEU211 |
| B | HOH297 |
| B | HOH507 |
| B | ALA76 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 301 |
| Chain | Residue |
| B | LEU183 |
| B | GLY185 |
| B | ARG187 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| B | GLY34 |
| B | GLY36 |
| C | GLN199 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 301 |
| Chain | Residue |
| A | ARG22 |
| A | HOH440 |
| C | LEU183 |
| C | ARG187 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 301 |
| Chain | Residue |
| B | ARG22 |
| D | LEU183 |
| D | GLY185 |
| D | ARG187 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 303 |
| Chain | Residue |
| D | HIS191 |
| D | GLY210 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 220 |
| Details | Domain: {"description":"MaoC-like","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| A | ILE207 | |
| A | ASP186 | |
| A | HIS191 | |
| A | GLY210 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| B | ILE207 | |
| B | ASP186 | |
| B | HIS191 | |
| B | GLY210 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| C | ILE207 | |
| C | ASP186 | |
| C | HIS191 | |
| C | GLY210 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| D | ILE207 | |
| D | ASP186 | |
| D | HIS191 | |
| D | GLY210 |
