3KHH

Dpo4 extension ternary complex with a C base opposite the 2-aminofluorene-guanine [AF]G lesion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006281	biological_process	DNA repair
B	0006974	biological_process	DNA damage response
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034061	molecular_function	DNA polymerase activity
B	0042276	biological_process	error-prone translesion synthesis
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE DGT A 414

Chain	Residue
A	ASP7
A	GLU106
A	LYS159
A	CA415
A	CA416
A	HOH515
A	HOH517
E	DA904
A	TYR10
A	PHE11
A	TYR12
A	VAL32
A	THR45
A	ARG51
A	LYS78
A	ASP105

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 415

Chain	Residue
A	ASP105
A	GLU106
A	DGT414
A	HOH543

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 416

Chain	Residue
A	ASP7
A	PHE8
A	ASP105
A	DGT414

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 417

Chain	Residue
A	ALA181
A	ILE186
A	HOH512
A	HOH513
A	HOH514
D	HOH515

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AF E 926

Chain	Residue
A	ILE248
A	VAL287
A	ARG336
E	DC905
E	DG906
E	DC907

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DGT B 1414

Chain	Residue
B	HOH22
B	HOH35
B	HOH103
B	ASP1007
B	PHE1008
B	TYR1010
B	PHE1011
B	THR1045
B	ARG1051
B	GLY1058
B	ASP1105
B	LYS1159
B	CA1415
B	CA1416
H	DOC1814
J	DC1905
J	DG1906

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA B 1415

Chain	Residue
B	HOH10
B	HOH103
B	ASP1105
B	GLU1106
B	DGT1414

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1416

Chain	Residue
B	HOH103
B	ASP1007
B	PHE1008
B	ASP1105
B	LYS1159
B	DGT1414

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 1417

Chain	Residue
B	HOH4
B	ALA1181
B	VAL1183
B	ILE1186
H	HOH2
H	DOC1814

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AF J 1926

Chain	Residue
B	LEU1293
B	ARG1332
J	DA1904
J	DC1905
J	DG1906

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	368
Details	Domain: {"description":"UmuC"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Substrate discrimination"}

Chain

Residue

Details

---