Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE 3TL A 200 |
| Chain | Residue |
| A | ARG8 |
| A | ILE50 |
| A | PRO81 |
| A | HOH265 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| A | ASP25 |
| B | ILE50 |
| B | VAL82 |
| B | ILE84 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | MET46 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS A 302 |
| Chain | Residue |
| A | LYS14 |
| A | ILE15 |
| A | GLY16 |
| A | GLY17 |
| A | LEU63 |
| A | ILE64 |
| A | GLU65 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 304 |
| Chain | Residue |
| A | TRP6 |
| B | LEU19 |
| B | ARG87 |
| B | ASN88 |
| B | HOH278 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME A 401 |
| Chain | Residue |
| A | VAL11 |
| A | THR12 |
| A | CYS67 |
| B | LYS7 |
| B | HOH254 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2FX B 201 |
| Chain | Residue |
| A | TRP6 |
| B | PRO44 |
| B | LYS45 |
| B | LYS55 |
| B | VAL56 |
| B | GLN92 |
| B | ILE93 |
| B | GLY94 |
| B | HOH208 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 305 |
| Chain | Residue |
| B | GLY73 |
| B | THR74 |
| B | ASN88 |
| B | GLN92 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BME B 402 |
| Chain | Residue |
| B | VAL11 |
| B | THR12 |
| B | CYS67 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
