Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE 3TL A 200 |
| Chain | Residue |
| A | TRP6 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PHE53 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | DMS303 |
| A | HOH358 |
| A | ARG8 |
| A | HOH364 |
| B | ARG8 |
| B | LEU23 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| A | ASP25 |
| B | PHE53 |
| B | PRO81 |
| B | VAL82 |
| B | ILE84 |
| B | HOH203 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | LYS45 |
| A | MET46 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 4DX A 201 |
| Chain | Residue |
| A | LYS14 |
| A | ILE15 |
| A | GLY16 |
| A | GLY17 |
| A | LEU63 |
| A | ILE64 |
| A | GLU65 |
| A | HOH301 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DMS A 303 |
| Chain | Residue |
| A | TRP6 |
| A | GLY49 |
| A | ILE50 |
| A | GLY51 |
| A | GLY52 |
| A | 3TL200 |
| B | ILE54 |
| B | PRO79 |
| B | PRO81 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 304 |
| Chain | Residue |
| A | GLY73 |
| A | THR74 |
| A | ASN88 |
| B | ARG41 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS A 305 |
| Chain | Residue |
| A | ARG87 |
| A | ASN88 |
| A | THR91 |
| B | LEU5 |
| B | TRP6 |
| B | ARG41 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 307 |
| Chain | Residue |
| A | GLY94 |
| A | THR96 |
| A | HOH355 |
| B | ASN98 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BME B 300 |
| Chain | Residue |
| A | GLN18 |
| A | ASN37 |
| B | THR12 |
| B | GLU65 |
| B | CYS67 |
| B | GLY68 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS B 302 |
| Chain | Residue |
| B | LYS14 |
| B | GLY16 |
| B | GLY17 |
| B | LEU63 |
| B | ILE64 |
| B | GLU65 |
| B | LYS70 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 306 |
| Chain | Residue |
| A | ASN98 |
| B | GLY94 |
| B | THR96 |
| B | HOH354 |
| B | HOH399 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
