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3KFF

Major mouse urinary protein IV complexed with 2-sec-butyl-4,5-dihydrothiazole

Functional Information from GO Data
ChainGOidnamespacecontents
A0005009molecular_functioninsulin receptor activity
A0005515molecular_functionprotein binding
A0005550molecular_functionpheromone binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005829cellular_componentcytosol
A0006112biological_processenergy reserve metabolic process
A0007005biological_processmitochondrion organization
A0008286biological_processinsulin receptor signaling pathway
A0009060biological_processaerobic respiration
A0010628biological_processpositive regulation of gene expression
A0010888biological_processnegative regulation of lipid storage
A0010907biological_processpositive regulation of glucose metabolic process
A0031649biological_processheat generation
A0036094molecular_functionsmall molecule binding
A0042593biological_processglucose homeostasis
A0045475biological_processlocomotor rhythm
A0045721biological_processnegative regulation of gluconeogenesis
A0045834biological_processpositive regulation of lipid metabolic process
A0045892biological_processnegative regulation of DNA-templated transcription
A0051055biological_processnegative regulation of lipid biosynthetic process
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0061179biological_processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
A0071396biological_processcellular response to lipid
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL A 201
ChainResidue
AARG156
ALEU158

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE XBT A 301
ChainResidue
AVAL40
APHE54
ALEU69
ATYR84
AGLU118
ATYR120
AHOH809

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ZBT A 302
ChainResidue
APHE54
APHE56
ALEU69
ATYR84
APHE90
ALEU116
AGLU118
ATYR120
AHOH809

Functional Information from PROSITE/UniProt
site_idPS00213
Number of Residues14
DetailsLIPOCALIN Lipocalin signature. NLNveKINGEWFSI
ChainResidueDetails
AASN9-ILE22

site_idPS00216
Number of Residues16
DetailsSUGAR_TRANSPORT_1 Sugar transport proteins signature 1. TFQLMELYGRKadln..S
ChainResidueDetails
ATHR113-SER128

224004

PDB entries from 2024-08-21

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