3KD9
Crystal structure of pyridine nucleotide disulfide oxidoreductase from Pyrococcus horikoshii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
| C | 0003756 | molecular_function | protein disulfide isomerase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 968 |
| Chain | Residue |
| A | ASP351 |
| C | SER271 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Redox-active => ECO:0000305|PubMed:23530771 |
| Chain | Residue | Details |
| A | CYS45 | |
| B | CYS45 | |
| C | CYS45 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 39 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23530771, ECO:0000269|PubMed:29988575, ECO:0007744|PDB:4FX9 |
| Chain | Residue | Details |
| A | ALA13 | |
| A | LYS358 | |
| A | TYR422 | |
| A | TRP430 | |
| A | ARG438 | |
| B | ALA13 | |
| B | ARG24 | |
| B | GLU35 | |
| B | SER41 | |
| B | HIS42 | |
| B | ARG72 | |
| A | ARG24 | |
| B | VAL82 | |
| B | ASP280 | |
| B | ASN302 | |
| B | LYS358 | |
| B | TYR422 | |
| B | TRP430 | |
| B | ARG438 | |
| C | ALA13 | |
| C | ARG24 | |
| C | GLU35 | |
| A | GLU35 | |
| C | SER41 | |
| C | HIS42 | |
| C | ARG72 | |
| C | VAL82 | |
| C | ASP280 | |
| C | ASN302 | |
| C | LYS358 | |
| C | TYR422 | |
| C | TRP430 | |
| C | ARG438 | |
| A | SER41 | |
| A | HIS42 | |
| A | ARG72 | |
| A | VAL82 | |
| A | ASP280 | |
| A | ASN302 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23530771, ECO:0007744|PDB:4FX9 |
| Chain | Residue | Details |
| A | TYR62 | |
| A | ALA298 | |
| B | TYR62 | |
| B | ALA298 | |
| C | TYR62 | |
| C | ALA298 |
