3KA9

Frog M-ferritin, EEH mutant, with cobalt

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CO A 176

Chain	Residue
A	HIS169
A	CL187
A	CL187
A	CL187
A	HIS169
A	HIS169
A	HIS169
A	CL185
A	CL185
A	CL185
A	CL185
A	CL187

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 177

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	HOH376
A	HOH381

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 178

Chain	Residue
A	GLU57
A	GLU136
A	HIS140
A	HOH355
A	HOH390

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 179

Chain	Residue
A	HIS56
A	GLU60
A	GLU63
A	HOH449
A	HOH450

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 180

Chain	Residue
A	HOH323
A	HOH323
A	HOH323
A	HOH378
A	HOH378
A	HOH378

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 181

Chain	Residue
A	HOH302
A	HOH302
A	HOH302
A	HOH405
A	HOH405
A	HOH405

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 182

Chain	Residue
A	HIS45
A	GLU49
A	HOH253
A	HOH304
A	HOH305

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 183

Chain	Residue
A	SER10
A	HOH220
A	HOH344
A	HOH420
A	HOH452
A	HOH453

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 184

Chain	Residue
A	HOH284
A	HOH418
A	HOH448
A	HOH454
A	HOH456
A	HOH475

---

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CL A 185

Chain	Residue
A	LEU165
A	LEU165
A	LEU165
A	LEU165
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	CO176
A	CO176
A	CO176
A	CO176

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 186

Chain	Residue
A	ASP87
A	GLU88

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CL A 187

Chain	Residue
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	CO176
A	CO176
A	CO176
A	CO176

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 188

Chain	Residue
A	HOH235
A	HOH235
A	HOH345
A	HOH345
A	HOH385
A	HOH385
A	HOH393
A	HOH393

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 189

Chain	Residue
A	ASN46
A	GLU49
A	HOH233
A	HOH293
A	HOH307

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 190

Chain	Residue
A	HOH308
A	HOH309
A	HOH310
A	HOH311
A	HOH379
A	HOH486

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 191

Chain	Residue
A	TYR8
A	ARG5
A	ASN7

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 192

Chain	Residue
A	SER131
A	GLU132
A	TYR133
A	GLU135
A	GLU136

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeevkhIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---