3K87
Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| A | 0009056 | biological_process | catabolic process |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| A | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| B | 0009056 | biological_process | catabolic process |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| B | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FAD A 600 |
| Chain | Residue |
| A | HOH2 |
| A | HOH341 |
| A | HOH348 |
| A | THR1048 |
| A | CYS1049 |
| A | SER1050 |
| A | ALA1051 |
| A | CYS1065 |
| A | ILE1066 |
| A | ASN1067 |
| A | LYS1069 |
| A | HOH147 |
| A | ALA1099 |
| A | HIS1145 |
| A | TYR1166 |
| A | HOH152 |
| A | HOH166 |
| A | HOH179 |
| A | HOH187 |
| A | HOH191 |
| A | HOH222 |
| A | HOH310 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FAD B 500 |
| Chain | Residue |
| B | THR48 |
| B | CYS49 |
| B | SER50 |
| B | ALA51 |
| B | CYS65 |
| B | ILE66 |
| B | ASN67 |
| B | SER70 |
| B | TYR71 |
| B | ALA99 |
| B | GLY100 |
| B | VAL104 |
| B | ARG109 |
| B | TYR166 |
| B | HOH190 |
| B | HOH248 |
| B | HOH255 |
| B | HOH284 |
| B | HOH285 |
| B | HOH304 |
| B | HOH305 |
| B | HOH373 |
| B | HOH376 |
| B | HOH377 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19915006 |
| Chain | Residue | Details |
| A | THR1048 | |
| B | SER54 | |
| B | CYS65 | |
| B | ALA99 | |
| B | VAL104 | |
| B | SER144 | |
| B | HIS145 | |
| B | TYR166 | |
| A | SER1054 | |
| A | CYS1065 | |
| A | ALA1099 | |
| A | VAL1104 | |
| A | SER1144 | |
| A | HIS1145 | |
| A | TYR1166 | |
| B | THR48 |
