3K7T

Crystal structure of apo-form 6-hydroxy-L-nicotine oxidase, crystal form P3121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0009820	biological_process	alkaloid metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0018531	molecular_function	(S)-6-hydroxynicotine oxidase activity
A	0019608	biological_process	nicotine catabolic process
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0009820	biological_process	alkaloid metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0018531	molecular_function	(S)-6-hydroxynicotine oxidase activity
B	0019608	biological_process	nicotine catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FAD A 434

Chain	Residue
A	GLY8
A	ARG39
A	ALA40
A	GLY56
A	GLY57
A	TYR59
A	THR224
A	VAL226
A	ALA254
A	THR255
A	PRO256
A	GLY10
A	LEU366
A	PHE367
A	TRP371
A	GLY397
A	SER398
A	GLY406
A	TYR407
A	ILE408
A	ALA411
A	PHE11
A	SER12
A	LEU30
A	GLU31
A	GLY32
A	GLY37
A	GLY38

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GP7 A 435

Chain	Residue
A	GLN99
A	ALA100
A	THR115
A	PHE159
A	LEU160
A	MET180
A	ILE191
A	LEU192
A	VAL195
B	ILE103
B	GLY105
B	ALA108

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site_id	AC3
Number of Residues	32
Details	BINDING SITE FOR RESIDUE FAD B 434

Chain	Residue
B	VAL7
B	GLY8
B	GLY10
B	PHE11
B	SER12
B	LEU30
B	GLU31
B	GLY32
B	GLY37
B	GLY38
B	ARG39
B	GLY56
B	GLY57
B	TYR59
B	THR224
B	VAL225
B	VAL226
B	ALA254
B	THR255
B	PRO256
B	ILE263
B	TRP361
B	LEU366
B	PHE367
B	PRO370
B	GLY397
B	SER398
B	GLY406
B	TYR407
B	ILE408
B	ALA411
B	HOH519

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GP7 B 435

Chain	Residue
A	ILE103
A	PRO104
A	GLY105
B	ALA100
B	VAL111
B	THR115
B	PHE159
B	LEU160
B	MET180
B	ILE191
B	LEU192
B	VAL195

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20006620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21383134","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3K7M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3K7Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3K7T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NG7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NGC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NH3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NHO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NK0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NK1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NK2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NN0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20006620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21383134","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3K7Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NG7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NGC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NH3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20006620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21383134","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NG7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NGC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NH3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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