3K5H
Crystal structure of carboxyaminoimidazole ribonucleotide synthase from asperigillus clavatus complexed with ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ATP A 400 |
| Chain | Residue |
| A | LYS104 |
| A | TRP183 |
| A | ALA184 |
| A | PHE186 |
| A | GLU189 |
| A | GLU254 |
| A | PHE256 |
| A | GLU267 |
| A | MG401 |
| A | MG402 |
| A | HOH423 |
| A | LYS146 |
| A | HOH432 |
| A | HOH445 |
| A | HOH476 |
| A | HOH477 |
| A | HOH496 |
| A | HOH526 |
| A | HOH566 |
| A | ALA151 |
| A | TYR152 |
| A | ASP153 |
| A | GLY154 |
| A | ASN157 |
| A | GLU181 |
| A | LYS182 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | GLU254 |
| A | GLU267 |
| A | ATP400 |
| A | HOH432 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | GLU267 |
| A | ATP400 |
| A | HOH423 |
| A | HOH445 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ATP B 400 |
| Chain | Residue |
| B | LYS104 |
| B | MET144 |
| B | LYS146 |
| B | ALA151 |
| B | TYR152 |
| B | ASP153 |
| B | GLY154 |
| B | ASN157 |
| B | GLU181 |
| B | LYS182 |
| B | TRP183 |
| B | ALA184 |
| B | GLU189 |
| B | GLU254 |
| B | GLU267 |
| B | MG401 |
| B | MG402 |
| B | HOH409 |
| B | HOH455 |
| B | HOH485 |
| B | HOH497 |
| B | HOH507 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 401 |
| Chain | Residue |
| B | GLU254 |
| B | GLU267 |
| B | ATP400 |
| B | HOH497 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 402 |
| Chain | Residue |
| B | GLU267 |
| B | ATP400 |
| B | HOH485 |
| B | HOH507 |
| site_id | AC7 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ATP C 400 |
| Chain | Residue |
| C | LYS104 |
| C | MET144 |
| C | LYS146 |
| C | TYR152 |
| C | ASP153 |
| C | GLY154 |
| C | ASN157 |
| C | GLU181 |
| C | LYS182 |
| C | TRP183 |
| C | ALA184 |
| C | PHE186 |
| C | GLU189 |
| C | GLN211 |
| C | GLU254 |
| C | GLU267 |
| C | HOH388 |
| C | HOH398 |
| C | MG401 |
| C | MG402 |
| C | HOH407 |
| C | HOH409 |
| C | HOH467 |
| C | HOH505 |
| C | HOH519 |
| C | HOH535 |
| C | HOH580 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 401 |
| Chain | Residue |
| C | GLU254 |
| C | GLU267 |
| C | HOH398 |
| C | ATP400 |
| C | MG402 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 402 |
| Chain | Residue |
| C | MG401 |
| C | HOH467 |
| C | GLU267 |
| C | HOH388 |
| C | ATP400 |
| site_id | BC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ATP D 400 |
| Chain | Residue |
| D | LYS104 |
| D | MET144 |
| D | LYS146 |
| D | ALA151 |
| D | TYR152 |
| D | ASP153 |
| D | GLY154 |
| D | ASN157 |
| D | GLU181 |
| D | LYS182 |
| D | TRP183 |
| D | ALA184 |
| D | GLU189 |
| D | GLU254 |
| D | CYS266 |
| D | GLU267 |
| D | HOH385 |
| D | MG401 |
| D | MG402 |
| D | HOH415 |
| D | HOH426 |
| D | HOH435 |
| D | HOH455 |
| D | HOH499 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 401 |
| Chain | Residue |
| D | GLU254 |
| D | GLU267 |
| D | ATP400 |
| D | MG402 |
| D | HOH455 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 402 |
| Chain | Residue |
| D | LYS104 |
| D | GLU267 |
| D | ATP400 |
| D | MG401 |
| D | HOH415 |
| D | HOH426 |
