3K2S
Solution structure of double super helix model
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001540 | molecular_function | amyloid-beta binding |
| A | 0002719 | biological_process | negative regulation of cytokine production involved in immune response |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005319 | molecular_function | lipid transporter activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005769 | cellular_component | early endosome |
| A | 0005788 | cellular_component | endoplasmic reticulum lumen |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006656 | biological_process | phosphatidylcholine biosynthetic process |
| A | 0006869 | biological_process | lipid transport |
| A | 0007179 | biological_process | transforming growth factor beta receptor signaling pathway |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0007229 | biological_process | integrin-mediated signaling pathway |
| A | 0008035 | molecular_function | high-density lipoprotein particle binding |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0008203 | biological_process | cholesterol metabolic process |
| A | 0008289 | molecular_function | lipid binding |
| A | 0010804 | biological_process | negative regulation of tumor necrosis factor-mediated signaling pathway |
| A | 0010875 | biological_process | positive regulation of cholesterol efflux |
| A | 0010903 | biological_process | negative regulation of very-low-density lipoprotein particle remodeling |
| A | 0015485 | molecular_function | cholesterol binding |
| A | 0018158 | biological_process | protein oxidation |
| A | 0018206 | biological_process | peptidyl-methionine modification |
| A | 0019899 | molecular_function | enzyme binding |
| A | 0030139 | cellular_component | endocytic vesicle |
| A | 0030301 | biological_process | cholesterol transport |
| A | 0031072 | molecular_function | heat shock protein binding |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0032489 | biological_process | regulation of Cdc42 protein signal transduction |
| A | 0032691 | biological_process | negative regulation of interleukin-1 beta production |
| A | 0033344 | biological_process | cholesterol efflux |
| A | 0033700 | biological_process | phospholipid efflux |
| A | 0034115 | biological_process | negative regulation of heterotypic cell-cell adhesion |
| A | 0034190 | molecular_function | apolipoprotein receptor binding |
| A | 0034191 | molecular_function | apolipoprotein A-I receptor binding |
| A | 0034205 | biological_process | amyloid-beta formation |
| A | 0034361 | cellular_component | very-low-density lipoprotein particle |
| A | 0034362 | cellular_component | low-density lipoprotein particle |
| A | 0034364 | cellular_component | high-density lipoprotein particle |
| A | 0034366 | cellular_component | spherical high-density lipoprotein particle |
| A | 0034375 | biological_process | high-density lipoprotein particle remodeling |
| A | 0034380 | biological_process | high-density lipoprotein particle assembly |
| A | 0034384 | biological_process | high-density lipoprotein particle clearance |
| A | 0034774 | cellular_component | secretory granule lumen |
| A | 0035025 | biological_process | positive regulation of Rho protein signal transduction |
| A | 0042627 | cellular_component | chylomicron |
| A | 0042632 | biological_process | cholesterol homeostasis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043691 | biological_process | reverse cholesterol transport |
| A | 0045499 | molecular_function | chemorepellent activity |
| A | 0048018 | molecular_function | receptor ligand activity |
| A | 0050728 | biological_process | negative regulation of inflammatory response |
| A | 0050766 | biological_process | positive regulation of phagocytosis |
| A | 0050821 | biological_process | protein stabilization |
| A | 0050919 | biological_process | negative chemotaxis |
| A | 0051180 | biological_process | vitamin transport |
| A | 0051496 | biological_process | positive regulation of stress fiber assembly |
| A | 0055090 | biological_process | acylglycerol homeostasis |
| A | 0055091 | biological_process | phospholipid homeostasis |
| A | 0060228 | molecular_function | phosphatidylcholine-sterol O-acyltransferase activator activity |
| A | 0060354 | biological_process | negative regulation of cell adhesion molecule production |
| A | 0060761 | biological_process | negative regulation of response to cytokine stimulus |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070328 | biological_process | triglyceride homeostasis |
| A | 0070371 | biological_process | ERK1 and ERK2 cascade |
| A | 0070508 | biological_process | cholesterol import |
| A | 0070653 | molecular_function | high-density lipoprotein particle receptor binding |
| A | 0071402 | biological_process | cellular response to lipoprotein particle stimulus |
| A | 0071682 | cellular_component | endocytic vesicle lumen |
| A | 0071813 | molecular_function | lipoprotein particle binding |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0090205 | biological_process | positive regulation of cholesterol metabolic process |
| A | 0120020 | molecular_function | cholesterol transfer activity |
| A | 1900026 | biological_process | positive regulation of substrate adhesion-dependent cell spreading |
| A | 1902995 | biological_process | positive regulation of phospholipid efflux |
| A | 1903561 | cellular_component | extracellular vesicle |
| B | 0001540 | molecular_function | amyloid-beta binding |
| B | 0002719 | biological_process | negative regulation of cytokine production involved in immune response |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0005319 | molecular_function | lipid transporter activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005543 | molecular_function | phospholipid binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005769 | cellular_component | early endosome |
| B | 0005788 | cellular_component | endoplasmic reticulum lumen |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006656 | biological_process | phosphatidylcholine biosynthetic process |
| B | 0006869 | biological_process | lipid transport |
| B | 0007179 | biological_process | transforming growth factor beta receptor signaling pathway |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0007229 | biological_process | integrin-mediated signaling pathway |
| B | 0008035 | molecular_function | high-density lipoprotein particle binding |
| B | 0008202 | biological_process | steroid metabolic process |
| B | 0008203 | biological_process | cholesterol metabolic process |
| B | 0008289 | molecular_function | lipid binding |
| B | 0010804 | biological_process | negative regulation of tumor necrosis factor-mediated signaling pathway |
| B | 0010875 | biological_process | positive regulation of cholesterol efflux |
| B | 0010903 | biological_process | negative regulation of very-low-density lipoprotein particle remodeling |
| B | 0015485 | molecular_function | cholesterol binding |
| B | 0018158 | biological_process | protein oxidation |
| B | 0018206 | biological_process | peptidyl-methionine modification |
| B | 0019899 | molecular_function | enzyme binding |
| B | 0030139 | cellular_component | endocytic vesicle |
| B | 0030301 | biological_process | cholesterol transport |
| B | 0031072 | molecular_function | heat shock protein binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0032489 | biological_process | regulation of Cdc42 protein signal transduction |
| B | 0032691 | biological_process | negative regulation of interleukin-1 beta production |
| B | 0033344 | biological_process | cholesterol efflux |
| B | 0033700 | biological_process | phospholipid efflux |
| B | 0034115 | biological_process | negative regulation of heterotypic cell-cell adhesion |
| B | 0034190 | molecular_function | apolipoprotein receptor binding |
| B | 0034191 | molecular_function | apolipoprotein A-I receptor binding |
| B | 0034205 | biological_process | amyloid-beta formation |
| B | 0034361 | cellular_component | very-low-density lipoprotein particle |
| B | 0034362 | cellular_component | low-density lipoprotein particle |
| B | 0034364 | cellular_component | high-density lipoprotein particle |
| B | 0034366 | cellular_component | spherical high-density lipoprotein particle |
| B | 0034375 | biological_process | high-density lipoprotein particle remodeling |
| B | 0034380 | biological_process | high-density lipoprotein particle assembly |
| B | 0034384 | biological_process | high-density lipoprotein particle clearance |
| B | 0034774 | cellular_component | secretory granule lumen |
| B | 0035025 | biological_process | positive regulation of Rho protein signal transduction |
| B | 0042627 | cellular_component | chylomicron |
| B | 0042632 | biological_process | cholesterol homeostasis |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043691 | biological_process | reverse cholesterol transport |
| B | 0045499 | molecular_function | chemorepellent activity |
| B | 0048018 | molecular_function | receptor ligand activity |
| B | 0050728 | biological_process | negative regulation of inflammatory response |
| B | 0050766 | biological_process | positive regulation of phagocytosis |
| B | 0050821 | biological_process | protein stabilization |
| B | 0050919 | biological_process | negative chemotaxis |
| B | 0051180 | biological_process | vitamin transport |
| B | 0051496 | biological_process | positive regulation of stress fiber assembly |
| B | 0055090 | biological_process | acylglycerol homeostasis |
| B | 0055091 | biological_process | phospholipid homeostasis |
| B | 0060228 | molecular_function | phosphatidylcholine-sterol O-acyltransferase activator activity |
| B | 0060354 | biological_process | negative regulation of cell adhesion molecule production |
| B | 0060761 | biological_process | negative regulation of response to cytokine stimulus |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0070328 | biological_process | triglyceride homeostasis |
| B | 0070371 | biological_process | ERK1 and ERK2 cascade |
| B | 0070508 | biological_process | cholesterol import |
| B | 0070653 | molecular_function | high-density lipoprotein particle receptor binding |
| B | 0071402 | biological_process | cellular response to lipoprotein particle stimulus |
| B | 0071682 | cellular_component | endocytic vesicle lumen |
| B | 0071813 | molecular_function | lipoprotein particle binding |
| B | 0072562 | cellular_component | blood microparticle |
| B | 0090205 | biological_process | positive regulation of cholesterol metabolic process |
| B | 0120020 | molecular_function | cholesterol transfer activity |
| B | 1900026 | biological_process | positive regulation of substrate adhesion-dependent cell spreading |
| B | 1902995 | biological_process | positive regulation of phospholipid efflux |
| B | 1903561 | cellular_component | extracellular vesicle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 301 |
| Chain | Residue |
| A | GLN5 |
| A | POV360 |
| A | POV367 |
| B | POV309 |
| B | POV366 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 302 |
| Chain | Residue |
| A | POV383 |
| A | POV351 |
| A | POV363 |
| A | POV368 |
| A | POV369 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 303 |
| Chain | Residue |
| A | GLN41 |
| A | LEU46 |
| A | ASN49 |
| A | POV365 |
| A | POV394 |
| B | POV339 |
| B | POV358 |
| B | POV373 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 304 |
| Chain | Residue |
| A | POV307 |
| A | POV326 |
| A | POV336 |
| A | POV378 |
| B | POV371 |
| B | CLR397 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 305 |
| Chain | Residue |
| A | POV306 |
| A | POV311 |
| A | POV312 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 306 |
| Chain | Residue |
| A | ARG177 |
| A | POV305 |
| A | POV337 |
| A | POV347 |
| A | CLR406 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 307 |
| Chain | Residue |
| A | POV304 |
| A | POV326 |
| A | POV337 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 308 |
| Chain | Residue |
| A | POV309 |
| A | POV314 |
| A | POV331 |
| A | POV337 |
| A | POV390 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE POV A 309 |
| Chain | Residue |
| A | ARG149 |
| A | POV308 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 310 |
| Chain | Residue |
| A | POV344 |
| A | POV375 |
| A | POV389 |
| B | POV321 |
| B | POV337 |
| B | POV364 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 311 |
| Chain | Residue |
| A | GLN172 |
| A | ARG177 |
| A | LEU178 |
| A | POV305 |
| A | POV312 |
| B | THR79 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 312 |
| Chain | Residue |
| A | LEU170 |
| A | GLN172 |
| A | POV305 |
| A | POV311 |
| A | POV347 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 313 |
| Chain | Residue |
| A | POV409 |
| A | POV411 |
| A | POV414 |
| A | POV415 |
| A | CLR421 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 314 |
| Chain | Residue |
| A | ASP150 |
| A | ALA152 |
| A | ARG153 |
| A | HIS155 |
| A | VAL156 |
| A | POV308 |
| A | POV337 |
| B | POV381 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 315 |
| Chain | Residue |
| A | POV316 |
| A | POV317 |
| A | POV364 |
| A | POV391 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 316 |
| Chain | Residue |
| A | LEU141 |
| A | POV315 |
| A | POV331 |
| B | POV305 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 317 |
| Chain | Residue |
| A | GLN127 |
| A | ARG131 |
| A | LEU134 |
| A | POV315 |
| A | POV318 |
| A | POV364 |
| B | POV304 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 318 |
| Chain | Residue |
| A | ARG123 |
| A | POV317 |
| A | POV333 |
| A | POV361 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 319 |
| Chain | Residue |
| A | TRP108 |
| A | MET112 |
| A | POV341 |
| A | POV361 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 320 |
| Chain | Residue |
| A | PHE104 |
| A | GLN105 |
| A | TRP108 |
| A | GLU111 |
| A | PRO99 |
| A | TYR100 |
| A | LEU101 |
| A | ASP102 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 321 |
| Chain | Residue |
| A | ASP89 |
| A | LEU90 |
| A | VAL93 |
| A | LYS94 |
| A | GLN98 |
| A | POV322 |
| A | POV335 |
| A | POV387 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 322 |
| Chain | Residue |
| A | MET86 |
| A | POV321 |
| A | POV392 |
| A | POV398 |
| A | POV399 |
| B | ARG177 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 323 |
| Chain | Residue |
| A | TRP72 |
| A | ASP73 |
| A | GLU76 |
| A | THR79 |
| A | POV353 |
| A | POV374 |
| B | ARG177 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 324 |
| Chain | Residue |
| A | LEU64 |
| A | POV330 |
| A | POV350 |
| A | POV362 |
| A | POV366 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 325 |
| Chain | Residue |
| A | POV330 |
| A | POV359 |
| A | POV381 |
| A | POV386 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 326 |
| Chain | Residue |
| A | POV304 |
| A | POV307 |
| A | POV390 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 327 |
| Chain | Residue |
| A | POV333 |
| A | POV364 |
| A | POV375 |
| A | POV389 |
| A | POV400 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 328 |
| Chain | Residue |
| A | POV339 |
| A | POV355 |
| A | POV392 |
| A | POV398 |
| A | POV399 |
| A | POV416 |
| site_id | DC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE POV A 329 |
| Chain | Residue |
| A | LEU82 |
| A | GLU85 |
| A | MET86 |
| A | LYS88 |
| A | ASP89 |
| A | GLU91 |
| A | GLU92 |
| A | ALA95 |
| A | LYS96 |
| A | POV398 |
| B | ARG171 |
| B | ARG173 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 330 |
| Chain | Residue |
| A | POV324 |
| A | POV325 |
| A | POV350 |
| A | POV354 |
| A | POV382 |
| A | POV384 |
| B | POV377 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 331 |
| Chain | Residue |
| A | POV308 |
| A | POV316 |
| A | POV391 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 332 |
| Chain | Residue |
| A | POV370 |
| A | POV372 |
| A | POV379 |
| B | POV335 |
| B | POV363 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 333 |
| Chain | Residue |
| A | POV318 |
| A | POV327 |
| A | POV343 |
| A | POV361 |
| A | CLR401 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 334 |
| Chain | Residue |
| A | POV335 |
| A | POV338 |
| A | POV370 |
| A | POV371 |
| A | CLR418 |
| B | POV336 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 335 |
| Chain | Residue |
| A | POV321 |
| A | POV334 |
| A | POV398 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 336 |
| Chain | Residue |
| A | POV304 |
| A | POV378 |
| B | POV331 |
| B | POV359 |
| B | CLR397 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 337 |
| Chain | Residue |
| A | POV306 |
| A | POV307 |
| A | POV308 |
| A | POV314 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 338 |
| Chain | Residue |
| A | POV334 |
| A | POV339 |
| A | POV370 |
| A | POV397 |
| A | CLR418 |
| B | POV336 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 339 |
| Chain | Residue |
| A | POV328 |
| A | POV338 |
| A | CLR403 |
| site_id | EC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE POV A 340 |
| Chain | Residue |
| A | POV371 |
| site_id | EC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 341 |
| Chain | Residue |
| A | POV319 |
| A | POV343 |
| A | POV371 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 342 |
| Chain | Residue |
| A | POV379 |
| A | POV407 |
| A | POV416 |
| A | CLR418 |
| B | POV315 |
| B | POV336 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 343 |
| Chain | Residue |
| A | POV333 |
| A | POV341 |
| A | POV344 |
| A | POV372 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 344 |
| Chain | Residue |
| A | POV310 |
| A | POV343 |
| A | POV373 |
| A | POV400 |
| A | CLR401 |
| site_id | EC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 345 |
| Chain | Residue |
| A | ARG215 |
| A | LEU219 |
| A | LEU222 |
| A | POV356 |
| A | POV377 |
| A | POV385 |
| B | TYR29 |
| site_id | FC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 346 |
| Chain | Residue |
| A | LEU181 |
| A | ARG188 |
| A | TYR192 |
| A | POV376 |
| A | POV378 |
| A | CLR406 |
| B | POV367 |
| B | POV368 |
| site_id | FC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 347 |
| Chain | Residue |
| A | LEU159 |
| A | ARG160 |
| A | POV306 |
| A | POV312 |
| B | POV338 |
| site_id | FC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE POV A 348 |
| Chain | Residue |
| A | POV354 |
| A | POV382 |
| site_id | FC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 349 |
| Chain | Residue |
| A | GLN69 |
| A | POV350 |
| A | POV374 |
| site_id | FC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 350 |
| Chain | Residue |
| A | POV324 |
| A | POV330 |
| A | POV349 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 351 |
| Chain | Residue |
| A | POV302 |
| A | POV383 |
| B | POV377 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 352 |
| Chain | Residue |
| A | POV360 |
| A | POV363 |
| A | POV388 |
| B | POV314 |
| B | POV382 |
| site_id | FC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 353 |
| Chain | Residue |
| A | TRP72 |
| A | POV323 |
| A | POV374 |
| A | POV399 |
| A | CLR404 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 354 |
| Chain | Residue |
| A | POV330 |
| A | POV348 |
| A | CLR404 |
| site_id | GC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 355 |
| Chain | Residue |
| A | POV328 |
| A | POV415 |
| A | POV416 |
| site_id | GC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV A 356 |
| Chain | Residue |
| A | TYR236 |
| A | POV345 |
| A | POV377 |
| A | POV385 |
| B | PRO4 |
| B | POV312 |
| B | POV322 |
| B | POV327 |
| B | POV385 |
| B | CLR394 |
| site_id | GC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 357 |
| Chain | Residue |
| A | SER25 |
| B | SER224 |
| B | THR242 |
| B | POV314 |
| B | POV349 |
| B | POV358 |
| B | POV382 |
| B | POV383 |
| site_id | GC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 358 |
| Chain | Residue |
| A | POV393 |
| A | POV407 |
| A | POV408 |
| A | POV413 |
| A | POV417 |
| A | CLR419 |
| B | POV372 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 359 |
| Chain | Residue |
| A | POV325 |
| A | POV369 |
| A | POV381 |
| A | POV384 |
| B | CLR398 |
| site_id | GC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 360 |
| Chain | Residue |
| A | POV301 |
| A | POV352 |
| A | POV367 |
| B | POV307 |
| B | POV314 |
| B | CLR393 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 361 |
| Chain | Residue |
| A | TYR115 |
| A | ARG116 |
| A | POV318 |
| A | POV319 |
| A | POV333 |
| site_id | GC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE POV A 362 |
| Chain | Residue |
| A | POV324 |
| site_id | GC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 363 |
| Chain | Residue |
| A | TYR29 |
| A | POV302 |
| A | POV352 |
| A | POV388 |
| site_id | HC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 364 |
| Chain | Residue |
| A | POV315 |
| A | POV317 |
| A | POV327 |
| A | POV389 |
| A | POV391 |
| site_id | HC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 365 |
| Chain | Residue |
| A | POV303 |
| A | POV368 |
| A | POV369 |
| site_id | HC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 366 |
| Chain | Residue |
| A | TRP50 |
| A | POV324 |
| A | POV369 |
| A | POV381 |
| A | POV386 |
| B | POV339 |
| site_id | HC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 367 |
| Chain | Residue |
| A | LYS12 |
| A | THR16 |
| A | TYR18 |
| A | POV301 |
| A | POV360 |
| site_id | HC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 368 |
| Chain | Residue |
| A | VAL30 |
| A | GLU34 |
| A | POV302 |
| A | POV365 |
| A | POV369 |
| A | POV394 |
| B | POV373 |
| site_id | HC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 369 |
| Chain | Residue |
| A | POV302 |
| A | POV359 |
| A | POV365 |
| A | POV366 |
| A | POV368 |
| A | POV394 |
| B | CLR398 |
| site_id | HC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 370 |
| Chain | Residue |
| A | POV332 |
| A | POV334 |
| A | POV338 |
| A | POV372 |
| A | POV379 |
| A | CLR403 |
| B | POV336 |
| site_id | HC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 371 |
| Chain | Residue |
| A | POV334 |
| A | POV340 |
| A | POV341 |
| A | POV372 |
| B | POV336 |
| site_id | HC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 372 |
| Chain | Residue |
| A | POV332 |
| A | POV343 |
| A | POV370 |
| A | POV371 |
| site_id | IC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 373 |
| Chain | Residue |
| A | POV344 |
| A | POV400 |
| B | CLR399 |
| site_id | IC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV A 374 |
| Chain | Residue |
| A | VAL67 |
| A | THR68 |
| A | GLN69 |
| A | PHE71 |
| A | TRP72 |
| A | ASP73 |
| A | LEU75 |
| A | POV323 |
| A | POV349 |
| A | POV353 |
| site_id | IC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 375 |
| Chain | Residue |
| A | POV310 |
| A | POV327 |
| A | POV389 |
| A | POV391 |
| site_id | IC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 376 |
| Chain | Residue |
| A | TYR192 |
| A | POV346 |
| A | POV378 |
| A | POV396 |
| A | CLR406 |
| site_id | IC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 377 |
| Chain | Residue |
| A | PHE225 |
| A | LYS226 |
| A | POV345 |
| A | POV356 |
| B | POV312 |
| site_id | IC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 378 |
| Chain | Residue |
| A | POV304 |
| A | POV336 |
| A | POV346 |
| A | POV376 |
| A | CLR406 |
| B | POV313 |
| B | POV371 |
| site_id | IC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 379 |
| Chain | Residue |
| A | POV332 |
| A | POV342 |
| A | POV370 |
| A | CLR418 |
| B | POV335 |
| B | POV336 |
| site_id | IC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 380 |
| Chain | Residue |
| A | PRO4 |
| A | TYR18 |
| B | GLN243 |
| B | POV366 |
| B | POV382 |
| B | POV383 |
| site_id | IC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 381 |
| Chain | Residue |
| A | POV325 |
| A | POV359 |
| A | POV366 |
| site_id | JC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 382 |
| Chain | Residue |
| A | POV330 |
| A | POV348 |
| A | POV409 |
| A | POV411 |
| site_id | JC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 383 |
| Chain | Residue |
| A | POV302 |
| A | POV351 |
| B | POV377 |
| B | POV389 |
| site_id | JC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 384 |
| Chain | Residue |
| A | POV330 |
| A | POV359 |
| A | POV412 |
| B | POV347 |
| B | POV377 |
| site_id | JC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 385 |
| Chain | Residue |
| A | POV345 |
| A | POV356 |
| B | POV312 |
| B | POV322 |
| B | POV331 |
| site_id | JC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 386 |
| Chain | Residue |
| A | POV325 |
| A | POV366 |
| A | POV409 |
| site_id | JC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV A 387 |
| Chain | Residue |
| A | LYS96 |
| A | TYR100 |
| A | POV321 |
| B | ASP168 |
| B | GLU169 |
| B | LEU170 |
| B | POV308 |
| B | POV324 |
| site_id | JC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 388 |
| Chain | Residue |
| A | POV352 |
| A | POV363 |
| B | POV333 |
| B | POV366 |
| site_id | JC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 389 |
| Chain | Residue |
| A | POV310 |
| A | POV327 |
| A | POV364 |
| A | POV375 |
| B | CLR391 |
| site_id | JC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 390 |
| Chain | Residue |
| A | POV308 |
| A | POV326 |
| A | POV391 |
| B | POV337 |
| site_id | KC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 391 |
| Chain | Residue |
| A | POV315 |
| A | POV331 |
| A | POV364 |
| A | POV375 |
| A | POV390 |
| B | CLR391 |
| site_id | KC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 392 |
| Chain | Residue |
| A | POV322 |
| A | POV328 |
| A | POV398 |
| A | POV399 |
| site_id | KC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 393 |
| Chain | Residue |
| A | POV358 |
| A | POV395 |
| A | POV413 |
| site_id | KC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 394 |
| Chain | Residue |
| A | ALA37 |
| A | LYS40 |
| A | POV303 |
| A | POV368 |
| A | POV369 |
| B | POV339 |
| B | POV373 |
| site_id | KC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 395 |
| Chain | Residue |
| A | POV393 |
| A | POV397 |
| A | POV407 |
| A | POV408 |
| site_id | KC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV A 396 |
| Chain | Residue |
| A | TYR192 |
| A | ALA196 |
| A | POV376 |
| B | PHE57 |
| B | POV313 |
| B | POV327 |
| B | POV385 |
| site_id | KC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 397 |
| Chain | Residue |
| A | POV338 |
| A | POV395 |
| A | POV408 |
| A | POV414 |
| A | POV415 |
| A | CLR419 |
| site_id | KC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV A 398 |
| Chain | Residue |
| A | POV322 |
| A | POV328 |
| A | POV329 |
| A | POV335 |
| A | POV392 |
| A | CLR403 |
| site_id | KC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 399 |
| Chain | Residue |
| A | POV322 |
| A | POV328 |
| A | POV353 |
| A | POV392 |
| site_id | LC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 400 |
| Chain | Residue |
| A | POV327 |
| A | POV344 |
| A | POV373 |
| A | CLR401 |
| site_id | LC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CLR A 401 |
| Chain | Residue |
| A | POV333 |
| A | POV344 |
| A | POV400 |
| site_id | LC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CLR A 402 |
| Chain | Residue |
| A | LEU203 |
| A | LYS206 |
| A | ALA210 |
| A | ASP213 |
| A | LEU214 |
| B | POV331 |
| site_id | LC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CLR A 403 |
| Chain | Residue |
| A | POV339 |
| A | POV370 |
| A | POV398 |
| site_id | LC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CLR A 404 |
| Chain | Residue |
| A | POV353 |
| A | POV354 |
| site_id | LC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CLR A 405 |
| Chain | Residue |
| A | POV410 |
| B | POV341 |
| site_id | LC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR A 406 |
| Chain | Residue |
| A | POV306 |
| A | POV346 |
| A | POV376 |
| A | POV378 |
| site_id | LC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 407 |
| Chain | Residue |
| A | POV342 |
| A | POV358 |
| A | POV395 |
| A | POV416 |
| B | POV315 |
| site_id | LC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 408 |
| Chain | Residue |
| A | POV358 |
| A | POV395 |
| A | POV397 |
| A | POV415 |
| A | CLR419 |
| site_id | MC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV A 409 |
| Chain | Residue |
| A | POV313 |
| A | POV382 |
| A | POV386 |
| site_id | MC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 410 |
| Chain | Residue |
| A | CLR405 |
| A | POV413 |
| B | POV341 |
| B | POV351 |
| B | POV372 |
| site_id | MC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 411 |
| Chain | Residue |
| A | POV313 |
| A | POV382 |
| A | POV414 |
| A | CLR419 |
| site_id | MC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE POV A 412 |
| Chain | Residue |
| A | POV384 |
| B | POV347 |
| site_id | MC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 413 |
| Chain | Residue |
| A | POV358 |
| A | POV393 |
| A | POV410 |
| A | POV417 |
| B | POV372 |
| site_id | MC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV A 414 |
| Chain | Residue |
| A | POV313 |
| A | POV397 |
| A | POV411 |
| A | CLR421 |
| site_id | MC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 415 |
| Chain | Residue |
| A | POV313 |
| A | POV355 |
| A | POV397 |
| A | POV408 |
| A | POV416 |
| site_id | MC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 416 |
| Chain | Residue |
| A | POV328 |
| A | POV342 |
| A | POV355 |
| A | POV407 |
| A | POV415 |
| site_id | MC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV A 417 |
| Chain | Residue |
| A | POV358 |
| A | POV413 |
| B | POV345 |
| B | POV350 |
| B | POV374 |
| site_id | NC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CLR A 418 |
| Chain | Residue |
| A | POV334 |
| A | POV338 |
| A | POV342 |
| A | POV379 |
| B | POV336 |
| site_id | NC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR A 419 |
| Chain | Residue |
| A | POV358 |
| A | POV397 |
| A | POV408 |
| A | POV411 |
| site_id | NC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CLR A 420 |
| Chain | Residue |
| B | POV352 |
| site_id | NC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CLR A 421 |
| Chain | Residue |
| A | POV313 |
| A | POV414 |
| B | POV374 |
| site_id | NC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 301 |
| Chain | Residue |
| B | GLY145 |
| B | GLU146 |
| B | ARG149 |
| B | ALA152 |
| B | POV379 |
| B | POV388 |
| B | CLR392 |
| site_id | NC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 302 |
| Chain | Residue |
| B | LEU134 |
| B | GLN138 |
| B | LEU141 |
| B | POV303 |
| B | POV323 |
| B | POV386 |
| B | POV387 |
| site_id | NC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE POV B 303 |
| Chain | Residue |
| A | LYS133 |
| B | GLN127 |
| B | GLU128 |
| B | ARG131 |
| B | LEU137 |
| B | POV302 |
| B | POV304 |
| B | POV323 |
| B | CLR395 |
| site_id | NC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 304 |
| Chain | Residue |
| A | POV317 |
| B | GLU120 |
| B | ARG123 |
| B | POV303 |
| B | POV305 |
| B | POV348 |
| B | CLR395 |
| site_id | NC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 305 |
| Chain | Residue |
| A | POV316 |
| B | MET112 |
| B | TYR115 |
| B | ARG116 |
| B | POV304 |
| B | POV340 |
| site_id | OC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 306 |
| Chain | Residue |
| B | ASP157 |
| B | LEU159 |
| B | POV369 |
| B | POV379 |
| B | POV388 |
| B | POV389 |
| site_id | OC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 307 |
| Chain | Residue |
| A | POV360 |
| B | POV318 |
| B | POV333 |
| B | POV369 |
| B | CLR393 |
| site_id | OC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 308 |
| Chain | Residue |
| A | POV387 |
| B | LEU170 |
| B | ARG171 |
| B | GLN172 |
| B | POV309 |
| B | POV318 |
| B | CLR393 |
| site_id | OC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 309 |
| Chain | Residue |
| A | POV301 |
| B | GLN172 |
| B | LEU178 |
| B | LYS182 |
| B | POV308 |
| site_id | OC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 310 |
| Chain | Residue |
| B | GLN98 |
| B | POV311 |
| B | CLR390 |
| site_id | OC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE POV B 311 |
| Chain | Residue |
| B | LYS94 |
| B | GLN98 |
| B | TYR100 |
| B | LEU101 |
| B | POV310 |
| B | POV325 |
| B | POV338 |
| B | POV343 |
| B | POV354 |
| site_id | OC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 312 |
| Chain | Residue |
| A | POV356 |
| A | POV377 |
| A | POV385 |
| B | POV313 |
| B | POV322 |
| B | POV331 |
| B | POV359 |
| site_id | OC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 313 |
| Chain | Residue |
| A | POV378 |
| A | POV396 |
| B | VAL53 |
| B | POV312 |
| B | POV331 |
| site_id | OC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV B 314 |
| Chain | Residue |
| A | POV352 |
| A | POV357 |
| A | POV360 |
| B | LEU189 |
| B | THR242 |
| B | POV366 |
| B | POV382 |
| B | POV383 |
| site_id | PC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 315 |
| Chain | Residue |
| A | POV342 |
| A | POV407 |
| B | POV356 |
| site_id | PC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 316 |
| Chain | Residue |
| B | GLN105 |
| B | TRP108 |
| B | POV340 |
| B | POV376 |
| B | POV384 |
| B | CLR390 |
| site_id | PC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 317 |
| Chain | Residue |
| B | POV352 |
| B | POV353 |
| B | POV356 |
| B | POV360 |
| site_id | PC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 318 |
| Chain | Residue |
| B | THR161 |
| B | POV307 |
| B | POV308 |
| site_id | PC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 319 |
| Chain | Residue |
| B | ARG83 |
| B | GLN84 |
| B | MET86 |
| B | SER87 |
| B | POV343 |
| B | POV354 |
| site_id | PC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 320 |
| Chain | Residue |
| B | POV332 |
| B | POV357 |
| B | POV360 |
| B | POV361 |
| B | POV362 |
| B | CLR396 |
| site_id | PC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE POV B 321 |
| Chain | Residue |
| A | POV310 |
| B | POV359 |
| site_id | PC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 322 |
| Chain | Residue |
| A | POV356 |
| A | POV385 |
| B | POV312 |
| B | POV331 |
| B | POV359 |
| B | POV385 |
| site_id | PC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 323 |
| Chain | Residue |
| B | POV302 |
| B | POV303 |
| B | POV348 |
| B | POV350 |
| B | POV351 |
| B | POV386 |
| site_id | QC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE POV B 324 |
| Chain | Residue |
| A | ASP102 |
| A | ASP103 |
| A | LYS106 |
| A | LYS107 |
| A | POV387 |
| B | VAL156 |
| B | ASP157 |
| B | ARG160 |
| B | HIS162 |
| B | SER167 |
| B | ASP168 |
| site_id | QC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 325 |
| Chain | Residue |
| B | POV311 |
| B | POV343 |
| B | POV376 |
| site_id | QC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 326 |
| Chain | Residue |
| B | POV361 |
| B | POV367 |
| B | POV371 |
| site_id | QC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 327 |
| Chain | Residue |
| A | POV356 |
| A | POV396 |
| B | LEU46 |
| B | TRP50 |
| B | POV331 |
| B | POV385 |
| site_id | QC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 328 |
| Chain | Residue |
| B | POV368 |
| B | POV370 |
| B | CLR394 |
| site_id | QC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV B 329 |
| Chain | Residue |
| B | ASP9 |
| B | VAL11 |
| B | LYS12 |
| B | VAL17 |
| B | TYR18 |
| B | VAL19 |
| B | POV359 |
| B | CLR394 |
| site_id | QC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 330 |
| Chain | Residue |
| B | POV334 |
| B | POV363 |
| B | POV364 |
| B | CLR399 |
| site_id | QC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE POV B 331 |
| Chain | Residue |
| A | LEU211 |
| A | LEU214 |
| A | POV336 |
| A | POV385 |
| A | CLR402 |
| B | LYS45 |
| B | ASN49 |
| B | POV312 |
| B | POV313 |
| B | POV322 |
| B | POV327 |
| B | POV385 |
| site_id | QC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 332 |
| Chain | Residue |
| B | POV320 |
| B | POV361 |
| B | POV362 |
| B | CLR396 |
| site_id | RC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 333 |
| Chain | Residue |
| A | POV388 |
| B | POV307 |
| B | POV369 |
| site_id | RC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 334 |
| Chain | Residue |
| B | POV330 |
| B | POV335 |
| B | POV356 |
| B | POV357 |
| B | POV363 |
| B | POV365 |
| site_id | RC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 335 |
| Chain | Residue |
| A | POV332 |
| A | POV379 |
| B | POV334 |
| B | POV363 |
| site_id | RC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 336 |
| Chain | Residue |
| A | POV334 |
| A | POV338 |
| A | POV342 |
| A | POV370 |
| A | POV371 |
| A | POV379 |
| A | CLR418 |
| site_id | RC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 337 |
| Chain | Residue |
| A | POV310 |
| A | POV390 |
| B | POV359 |
| B | CLR397 |
| site_id | RC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE POV B 338 |
| Chain | Residue |
| A | ASP157 |
| A | ARG160 |
| A | POV347 |
| B | GLU91 |
| B | GLU92 |
| B | VAL93 |
| B | LYS96 |
| B | VAL97 |
| B | POV311 |
| B | POV354 |
| B | POV381 |
| site_id | RC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE POV B 339 |
| Chain | Residue |
| A | POV303 |
| A | POV366 |
| A | POV394 |
| B | LEU200 |
| B | SER201 |
| B | LEU203 |
| B | SER204 |
| B | ALA207 |
| B | POV349 |
| B | POV358 |
| B | POV373 |
| site_id | RC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 340 |
| Chain | Residue |
| B | POV305 |
| B | POV316 |
| B | POV381 |
| site_id | RC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 341 |
| Chain | Residue |
| A | CLR405 |
| A | POV410 |
| B | POV342 |
| B | POV352 |
| B | POV353 |
| site_id | SC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 342 |
| Chain | Residue |
| B | POV341 |
| B | POV343 |
| B | POV353 |
| site_id | SC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 343 |
| Chain | Residue |
| B | POV311 |
| B | POV319 |
| B | POV325 |
| B | POV342 |
| B | POV353 |
| B | POV354 |
| site_id | SC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 344 |
| Chain | Residue |
| B | POV345 |
| B | POV346 |
| B | POV374 |
| B | POV378 |
| B | POV380 |
| B | POV388 |
| site_id | SC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 345 |
| Chain | Residue |
| A | POV417 |
| B | POV344 |
| B | POV350 |
| B | POV374 |
| B | POV378 |
| B | POV387 |
| site_id | SC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 346 |
| Chain | Residue |
| B | POV344 |
| B | POV347 |
| B | POV374 |
| B | POV378 |
| B | POV379 |
| B | POV380 |
| B | POV388 |
| site_id | SC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 347 |
| Chain | Residue |
| A | POV384 |
| A | POV412 |
| B | POV346 |
| B | POV374 |
| B | POV377 |
| B | POV379 |
| site_id | SC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 348 |
| Chain | Residue |
| B | POV304 |
| B | POV323 |
| B | POV384 |
| B | CLR395 |
| site_id | SC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 349 |
| Chain | Residue |
| A | POV357 |
| B | GLY217 |
| B | PHE225 |
| B | POV339 |
| B | POV358 |
| B | POV382 |
| site_id | SC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 350 |
| Chain | Residue |
| A | POV417 |
| B | POV323 |
| B | POV345 |
| B | POV351 |
| B | POV378 |
| B | POV386 |
| site_id | TC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 351 |
| Chain | Residue |
| A | POV410 |
| B | POV323 |
| B | POV350 |
| B | POV372 |
| B | POV375 |
| B | POV384 |
| site_id | TC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 352 |
| Chain | Residue |
| A | CLR420 |
| B | POV317 |
| B | POV341 |
| B | POV353 |
| site_id | TC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 353 |
| Chain | Residue |
| B | POV317 |
| B | POV341 |
| B | POV342 |
| B | POV343 |
| B | POV352 |
| B | POV356 |
| site_id | TC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV B 354 |
| Chain | Residue |
| B | MET86 |
| B | ASP89 |
| B | LEU90 |
| B | VAL93 |
| B | POV311 |
| B | POV319 |
| B | POV338 |
| B | POV343 |
| site_id | TC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 355 |
| Chain | Residue |
| B | POV364 |
| B | POV365 |
| B | POV370 |
| B | POV371 |
| site_id | TC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 356 |
| Chain | Residue |
| B | POV315 |
| B | POV317 |
| B | POV334 |
| B | POV353 |
| site_id | TC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 357 |
| Chain | Residue |
| B | POV320 |
| B | POV334 |
| B | POV360 |
| B | POV365 |
| B | CLR396 |
| site_id | TC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE POV B 358 |
| Chain | Residue |
| A | POV303 |
| A | POV357 |
| B | LEU214 |
| B | ARG215 |
| B | GLN216 |
| B | GLY217 |
| B | LEU218 |
| B | POV339 |
| B | POV349 |
| B | POV373 |
| B | POV382 |
| B | POV383 |
| site_id | TC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 359 |
| Chain | Residue |
| A | POV336 |
| B | SER6 |
| B | POV312 |
| B | POV321 |
| B | POV322 |
| B | POV329 |
| B | POV337 |
| site_id | UC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 360 |
| Chain | Residue |
| B | POV317 |
| B | POV320 |
| B | POV357 |
| site_id | UC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE POV B 361 |
| Chain | Residue |
| A | ARG177 |
| B | GLN69 |
| B | GLU70 |
| B | PHE71 |
| B | TRP72 |
| B | ASP73 |
| B | POV320 |
| B | POV326 |
| B | POV332 |
| B | POV362 |
| B | POV367 |
| site_id | UC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV B 362 |
| Chain | Residue |
| B | ASP73 |
| B | LEU75 |
| B | GLU76 |
| B | LYS77 |
| B | THR79 |
| B | GLU80 |
| B | ARG83 |
| B | POV320 |
| B | POV332 |
| B | POV361 |
| site_id | UC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 363 |
| Chain | Residue |
| A | POV332 |
| B | POV330 |
| B | POV334 |
| B | POV335 |
| site_id | UC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 364 |
| Chain | Residue |
| A | POV310 |
| B | LYS12 |
| B | POV330 |
| B | POV355 |
| B | POV365 |
| site_id | UC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 365 |
| Chain | Residue |
| B | POV334 |
| B | POV355 |
| B | POV357 |
| B | POV364 |
| B | CLR396 |
| site_id | UC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 366 |
| Chain | Residue |
| A | POV301 |
| A | POV380 |
| A | POV388 |
| B | LYS182 |
| B | POV314 |
| site_id | UC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV B 367 |
| Chain | Residue |
| A | POV346 |
| B | ARG61 |
| B | LEU64 |
| B | THR68 |
| B | GLN69 |
| B | PHE71 |
| B | TRP72 |
| B | POV326 |
| B | POV361 |
| B | POV368 |
| site_id | UC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 368 |
| Chain | Residue |
| A | POV346 |
| B | PHE57 |
| B | POV328 |
| B | POV367 |
| site_id | VC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 369 |
| Chain | Residue |
| B | POV306 |
| B | POV307 |
| B | POV333 |
| B | POV389 |
| site_id | VC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 370 |
| Chain | Residue |
| B | POV355 |
| B | POV371 |
| B | POV328 |
| site_id | VC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 371 |
| Chain | Residue |
| A | POV304 |
| A | POV378 |
| B | POV326 |
| B | POV355 |
| B | POV370 |
| site_id | VC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 372 |
| Chain | Residue |
| A | POV358 |
| A | POV410 |
| A | POV413 |
| B | POV351 |
| site_id | VC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE POV B 373 |
| Chain | Residue |
| A | LYS40 |
| A | POV303 |
| A | POV368 |
| A | POV394 |
| B | ALA207 |
| B | LYS208 |
| B | PRO209 |
| B | ASP213 |
| B | LEU214 |
| B | POV339 |
| B | POV358 |
| B | POV382 |
| site_id | VC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 374 |
| Chain | Residue |
| A | POV417 |
| A | CLR421 |
| B | POV344 |
| B | POV345 |
| B | POV346 |
| B | POV347 |
| site_id | VC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 375 |
| Chain | Residue |
| B | POV351 |
| B | POV376 |
| B | POV384 |
| site_id | VC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POV B 376 |
| Chain | Residue |
| B | POV316 |
| B | POV325 |
| B | POV375 |
| site_id | VC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 377 |
| Chain | Residue |
| A | POV330 |
| A | POV351 |
| A | POV383 |
| A | POV384 |
| B | POV347 |
| site_id | WC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POV B 378 |
| Chain | Residue |
| B | POV344 |
| B | POV345 |
| B | POV346 |
| B | POV350 |
| B | POV380 |
| B | POV386 |
| B | POV387 |
| B | CLR392 |
| site_id | WC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE POV B 379 |
| Chain | Residue |
| B | POV301 |
| B | POV306 |
| B | POV346 |
| B | POV347 |
| B | POV380 |
| B | POV388 |
| B | POV389 |
| site_id | WC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 380 |
| Chain | Residue |
| B | POV344 |
| B | POV346 |
| B | POV378 |
| B | POV379 |
| B | POV388 |
| B | CLR392 |
| site_id | WC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE POV B 381 |
| Chain | Residue |
| A | HIS155 |
| A | ASP157 |
| A | ALA158 |
| A | POV314 |
| B | PRO99 |
| B | TYR100 |
| B | ASP102 |
| B | ASP103 |
| B | PHE104 |
| B | LYS107 |
| B | POV338 |
| B | POV340 |
| site_id | WC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV B 382 |
| Chain | Residue |
| A | POV352 |
| A | POV357 |
| A | POV380 |
| B | HIS193 |
| B | THR197 |
| B | POV314 |
| B | POV349 |
| B | POV358 |
| B | POV373 |
| B | POV383 |
| site_id | WC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE POV B 383 |
| Chain | Residue |
| A | VAL21 |
| A | POV357 |
| A | POV380 |
| B | LEU189 |
| B | PHE225 |
| B | SER228 |
| B | PHE229 |
| B | LYS238 |
| B | THR242 |
| B | GLN243 |
| B | POV314 |
| B | POV358 |
| B | POV382 |
| site_id | WC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 384 |
| Chain | Residue |
| B | POV316 |
| B | POV348 |
| B | POV351 |
| B | POV375 |
| site_id | WC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE POV B 385 |
| Chain | Residue |
| A | POV356 |
| A | POV396 |
| B | POV322 |
| B | POV327 |
| B | POV331 |
| B | CLR394 |
| site_id | WC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 386 |
| Chain | Residue |
| B | POV302 |
| B | POV323 |
| B | POV350 |
| B | POV378 |
| B | POV387 |
| site_id | XC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POV B 387 |
| Chain | Residue |
| B | POV302 |
| B | POV345 |
| B | POV378 |
| B | POV386 |
| B | CLR392 |
| site_id | XC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POV B 388 |
| Chain | Residue |
| B | ARG149 |
| B | ASP150 |
| B | ARG153 |
| B | VAL156 |
| B | POV301 |
| B | POV306 |
| B | POV344 |
| B | POV346 |
| B | POV379 |
| B | POV380 |
| site_id | XC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE POV B 389 |
| Chain | Residue |
| A | POV383 |
| B | POV306 |
| B | POV369 |
| B | POV379 |
| site_id | XC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CLR B 390 |
| Chain | Residue |
| B | LEU101 |
| B | PHE104 |
| B | TRP108 |
| B | POV310 |
| B | POV316 |
| site_id | XC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CLR B 391 |
| Chain | Residue |
| A | POV389 |
| A | POV391 |
| site_id | XC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR B 392 |
| Chain | Residue |
| B | POV301 |
| B | POV378 |
| B | POV380 |
| B | POV387 |
| site_id | XC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CLR B 393 |
| Chain | Residue |
| A | POV360 |
| B | POV307 |
| B | POV308 |
| site_id | XC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR B 394 |
| Chain | Residue |
| A | POV356 |
| B | POV328 |
| B | POV329 |
| B | POV385 |
| site_id | XC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR B 395 |
| Chain | Residue |
| B | GLN127 |
| B | POV303 |
| B | POV304 |
| B | POV348 |
| site_id | YC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CLR B 396 |
| Chain | Residue |
| B | POV320 |
| B | POV332 |
| B | POV357 |
| B | POV365 |
| site_id | YC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CLR B 397 |
| Chain | Residue |
| A | POV304 |
| A | POV336 |
| B | POV337 |
| site_id | YC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CLR B 398 |
| Chain | Residue |
| A | POV359 |
| A | POV369 |
| site_id | YC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CLR B 399 |
| Chain | Residue |
| A | POV373 |
| B | POV330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Repeat: {"description":"3; half-length"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"8"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Repeat: {"description":"9; half-length"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"10"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 398 |
| Details | Region: {"description":"10 X approximate tandem repeats"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Methionine sulfoxide","evidences":[{"source":"PubMed","id":"12576517","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (Glc) (glycation) lysine","evidences":[{"source":"PubMed","id":"8261628","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
