3K2I

Human Acyl-coenzyme A thioesterase 4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000038	biological_process	very long-chain fatty acid metabolic process
A	0001676	biological_process	long-chain fatty acid metabolic process
A	0004778	molecular_function	succinyl-CoA hydrolase activity
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006104	biological_process	succinyl-CoA metabolic process
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0006637	biological_process	acyl-CoA metabolic process
A	0016787	molecular_function	hydrolase activity
A	0016790	molecular_function	thiolester hydrolase activity
A	0019605	biological_process	butyrate metabolic process
A	0032787	biological_process	monocarboxylic acid metabolic process
A	0032788	biological_process	saturated monocarboxylic acid metabolic process
A	0032789	biological_process	unsaturated monocarboxylic acid metabolic process
A	0043648	biological_process	dicarboxylic acid metabolic process
A	0043649	biological_process	dicarboxylic acid catabolic process
A	0046459	biological_process	short-chain fatty acid metabolic process
A	0047617	molecular_function	fatty acyl-CoA hydrolase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
B	0000038	biological_process	very long-chain fatty acid metabolic process
B	0001676	biological_process	long-chain fatty acid metabolic process
B	0004778	molecular_function	succinyl-CoA hydrolase activity
B	0005777	cellular_component	peroxisome
B	0005782	cellular_component	peroxisomal matrix
B	0005829	cellular_component	cytosol
B	0006104	biological_process	succinyl-CoA metabolic process
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0006637	biological_process	acyl-CoA metabolic process
B	0016787	molecular_function	hydrolase activity
B	0016790	molecular_function	thiolester hydrolase activity
B	0019605	biological_process	butyrate metabolic process
B	0032787	biological_process	monocarboxylic acid metabolic process
B	0032788	biological_process	saturated monocarboxylic acid metabolic process
B	0032789	biological_process	unsaturated monocarboxylic acid metabolic process
B	0043648	biological_process	dicarboxylic acid metabolic process
B	0043649	biological_process	dicarboxylic acid catabolic process
B	0046459	biological_process	short-chain fatty acid metabolic process
B	0047617	molecular_function	fatty acyl-CoA hydrolase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NI A 422

Chain	Residue
B	LEU289

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 423

Chain	Residue
A	HOH492

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 423

Chain	Residue
B	HOH526

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"P49753","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q8BWN8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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