3JZA
Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 365 |
| Chain | Residue |
| A | GLY18 |
| A | VAL19 |
| A | GLY20 |
| A | SER22 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL |
| Chain | Residue | Details |
| A | LEU11-LEU24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| A | SER17 | |
| A | LYS153 | |
| A | GLY20 | |
| A | LYS21 | |
| A | CYS23 | |
| A | GLU35 | |
| A | GLY66 | |
| A | ASN121 | |
| A | ASP124 | |
| A | ALA152 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27552051, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| A | GLY18 | |
| A | LYS122 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3NKV |
| Chain | Residue | Details |
| A | VAL19 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:3NKV, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:4I1O, ECO:0007744|PDB:5SZH, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| A | SER22 | |
| A | THR40 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27552051, ECO:0007744|PDB:5SZH |
| Chain | Residue | Details |
| A | TYR33 | |
| A | SER39 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20651120, ECO:0007744|PDB:3NKV |
| Chain | Residue | Details |
| A | THR34 | |
| A | SER36 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23236136, ECO:0000269|PubMed:27552051, ECO:0007744|PDB:4HLQ, ECO:0007744|PDB:5SZH |
| Chain | Residue | Details |
| A | ASP63 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27552051, ECO:0007744|PDB:5SZK |
| Chain | Residue | Details |
| A | SER151 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-(2-cholinephosphoryl)serine => ECO:0000269|PubMed:21822290, ECO:0000269|PubMed:22158903, ECO:0000269|PubMed:22307087 |
| Chain | Residue | Details |
| A | SER76 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-AMP-tyrosine => ECO:0000269|PubMed:20651120 |
| Chain | Residue | Details |
| A | TYR77 |
