3JYQ

Quinate dehydrogenase from Corynebacterium glutamicum in complex with shikimate and NADH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019632	biological_process	shikimate metabolic process
A	0030266	molecular_function	quinate 3-dehydrogenase (NAD+) activity
A	0052734	molecular_function	shikimate 3-dehydrogenase (NAD+) activity
A	0070403	molecular_function	NAD+ binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE NAD A 377

Chain	Residue
A	VAL133
A	PRO203
A	MET206
A	ALA213
A	VAL228
A	VAL229
A	GLY251
A	ALA255
A	HOH388
A	HOH447
A	HOH588
A	GLY136
A	HOH590
A	HOH636
A	HOH667
A	GLY137
A	VAL138
A	ASP158
A	LEU159
A	ARG163
A	ALA201
A	THR202

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SKM A 378

Chain	Residue
A	LEU9
A	SER17
A	THR19
A	ASN67
A	THR69
A	LYS73
A	ASN94
A	ASP110
A	GLN258
A	HOH459
A	HOH619

---

Functional Information from PROSITE/UniProt

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. LkTLLDAALYLG

Chain	Residue	Details
A	LEU51-GLY62

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:23929881

Chain	Residue	Details
A	LYS73

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	SER17
A	THR69
A	LYS73
A	ASN94
A	ASP110
A	GLN258

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYO, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	GLY137
A	VAL228
A	GLY251

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYO, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	ASP158
A	ARG163
A	PRO203

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:23929881, ECO:0007744|PDB:3JYP, ECO:0007744|PDB:3JYQ

Chain	Residue	Details
A	ALA213

---