3JVM
Crystal structure of bromodomain 2 of mouse Brd4
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BME A 1 |
| Chain | Residue |
| A | HOH65 |
| A | HOH108 |
| A | CYS357 |
| A | ARG454 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME A 465 |
| Chain | Residue |
| A | CYS392 |
| A | ILE395 |
| A | LYS396 |
| A | PRO398 |
| A | EDO467 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 466 |
| Chain | Residue |
| A | HOH143 |
| A | ILE394 |
| A | ILE395 |
| A | LYS396 |
| A | HIS397 |
| A | ASN429 |
| A | LYS432 |
| A | ASP460 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 467 |
| Chain | Residue |
| A | HOH112 |
| A | PRO380 |
| A | VAL381 |
| A | BME465 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 109 |
| Details | Domain: {"description":"Bromo 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"UniProtKB","id":"O60885","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
