3JQM
Binding of 5'-GTP to molybdenum cofactor biosynthesis protein MoaC from Thermus theromophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| C | 0005525 | molecular_function | GTP binding |
| C | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| D | 0005525 | molecular_function | GTP binding |
| D | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| E | 0005525 | molecular_function | GTP binding |
| E | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| F | 0005525 | molecular_function | GTP binding |
| F | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| G | 0005525 | molecular_function | GTP binding |
| G | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| G | 0016829 | molecular_function | lyase activity |
| G | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| H | 0005525 | molecular_function | GTP binding |
| H | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| H | 0016829 | molecular_function | lyase activity |
| H | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
| I | 0005525 | molecular_function | GTP binding |
| I | 0006777 | biological_process | Mo-molybdopterin cofactor biosynthetic process |
| I | 0016829 | molecular_function | lyase activity |
| I | 0061799 | molecular_function | cyclic pyranopterin monophosphate synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP A 158 |
| Chain | Residue |
| A | VAL14 |
| A | FLC159 |
| A | HOH234 |
| A | HOH341 |
| A | HOH374 |
| A | HOH446 |
| A | HOH597 |
| H | GLU18 |
| H | LYS149 |
| A | VAL47 |
| A | LYS49 |
| A | CYS74 |
| A | HIS75 |
| A | THR107 |
| A | ASP126 |
| A | LYS129 |
| A | ALA130 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC A 159 |
| Chain | Residue |
| A | LYS19 |
| A | ARG24 |
| A | GLU106 |
| A | GLU110 |
| A | LYS133 |
| A | LYS145 |
| A | LYS149 |
| A | SER150 |
| A | GTP158 |
| A | HOH447 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 160 |
| Chain | Residue |
| A | ARG94 |
| A | ARG141 |
| E | ARG141 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 161 |
| Chain | Residue |
| A | LEU88 |
| A | LYS90 |
| B | ARG10 |
| E | ARG85 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 162 |
| Chain | Residue |
| A | ARG85 |
| A | THR100 |
| E | ARG10 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 163 |
| Chain | Residue |
| A | LEU42 |
| A | ASP51 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 164 |
| Chain | Residue |
| A | ALA64 |
| A | LYS65 |
| A | LYS66 |
| A | THR67 |
| A | ALA68 |
| A | PRO76 |
| A | LEU77 |
| B | PEG163 |
| E | PEG160 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 165 |
| Chain | Residue |
| A | VAL54 |
| A | VAL86 |
| A | HOH300 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GTP B 158 |
| Chain | Residue |
| B | GLU36 |
| B | SER40 |
| B | VAL47 |
| B | LYS49 |
| B | ASP126 |
| B | LYS129 |
| B | ALA130 |
| B | HOH305 |
| B | HOH388 |
| E | VAL14 |
| E | CYS74 |
| E | HIS75 |
| E | FLC159 |
| E | HOH444 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FLC B 159 |
| Chain | Residue |
| B | LYS19 |
| B | ARG24 |
| B | LYS145 |
| B | LYS149 |
| B | SER150 |
| D | LYS149 |
| E | LYS133 |
| E | GTP158 |
| E | HOH442 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 160 |
| Chain | Residue |
| A | ARG10 |
| B | GLU83 |
| B | ARG85 |
| B | THR100 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 161 |
| Chain | Residue |
| B | HOH391 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 162 |
| Chain | Residue |
| A | ASP69 |
| B | LYS66 |
| B | ASP69 |
| E | LYS66 |
| E | ASP69 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG B 163 |
| Chain | Residue |
| A | PEG164 |
| B | ALA64 |
| B | LYS65 |
| B | THR67 |
| B | ALA68 |
| B | PRO76 |
| B | LEU77 |
| site_id | BC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GTP C 158 |
| Chain | Residue |
| G | HIS75 |
| G | THR107 |
| C | VAL47 |
| C | LYS49 |
| C | ASP126 |
| C | LYS129 |
| C | ALA130 |
| C | HOH527 |
| G | VAL14 |
| G | CYS74 |
| site_id | BC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE FLC C 159 |
| Chain | Residue |
| C | LYS19 |
| C | ARG24 |
| C | GLU106 |
| C | THR107 |
| C | GLY108 |
| C | GLU110 |
| C | LYS145 |
| C | LYS149 |
| C | SER150 |
| G | LYS133 |
| G | GTP158 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 160 |
| Chain | Residue |
| C | GLU83 |
| C | ARG85 |
| C | EDO161 |
| C | HOH338 |
| I | LYS90 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 161 |
| Chain | Residue |
| C | ARG85 |
| C | GLU98 |
| C | THR100 |
| C | GOL160 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG C 162 |
| Chain | Residue |
| C | ALA64 |
| C | LYS65 |
| C | ALA68 |
| C | PRO76 |
| C | LEU77 |
| C | GLU112 |
| site_id | CC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GTP D 158 |
| Chain | Residue |
| D | VAL47 |
| D | GLY48 |
| D | LYS49 |
| D | ASP126 |
| D | LYS129 |
| D | ALA130 |
| D | HOH267 |
| F | VAL14 |
| F | CYS74 |
| F | HIS75 |
| F | THR107 |
| F | GLY108 |
| F | MET111 |
| F | FLC159 |
| site_id | CC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE FLC D 159 |
| Chain | Residue |
| D | LYS19 |
| D | ARG24 |
| D | GLU106 |
| D | THR107 |
| D | GLY108 |
| D | GLU110 |
| D | LYS145 |
| D | GLY148 |
| D | LYS149 |
| D | SER150 |
| D | HOH361 |
| F | LYS129 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 160 |
| Chain | Residue |
| D | GLU83 |
| D | GLU98 |
| D | ALA99 |
| D | THR100 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 161 |
| Chain | Residue |
| C | LEU77 |
| D | PRO78 |
| H | PRO76 |
| H | LEU77 |
| H | PRO78 |
| site_id | CC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GTP E 158 |
| Chain | Residue |
| B | VAL14 |
| B | CYS74 |
| B | HIS75 |
| B | THR107 |
| B | MET111 |
| B | FLC159 |
| D | LYS149 |
| E | VAL47 |
| E | GLY48 |
| E | LYS49 |
| E | ASP126 |
| E | LYS129 |
| E | ALA130 |
| E | HOH225 |
| E | HOH262 |
| E | HOH372 |
| E | HOH442 |
| E | HOH443 |
| E | HOH462 |
| F | GTP158 |
| site_id | CC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FLC E 159 |
| Chain | Residue |
| B | GTP158 |
| E | ARG24 |
| E | THR107 |
| E | GLY108 |
| E | GLU110 |
| E | LYS145 |
| E | GLY147 |
| E | SER150 |
| E | HOH514 |
| E | HOH599 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG E 160 |
| Chain | Residue |
| A | PEG164 |
| E | LYS65 |
| E | ALA68 |
| E | PRO76 |
| E | LEU77 |
| E | GLU112 |
| site_id | CC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GTP F 158 |
| Chain | Residue |
| D | VAL14 |
| D | CYS74 |
| D | HIS75 |
| D | THR107 |
| D | HOH298 |
| D | HOH361 |
| E | GLU37 |
| E | GTP158 |
| F | VAL47 |
| F | GLY48 |
| F | LYS49 |
| F | ASP126 |
| F | LYS129 |
| F | ALA130 |
| F | HOH265 |
| F | HOH586 |
| site_id | DC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FLC F 159 |
| Chain | Residue |
| D | LYS133 |
| D | GTP158 |
| F | ARG24 |
| F | GLU110 |
| F | LYS145 |
| F | GLY147 |
| F | GLY148 |
| F | LYS149 |
| F | SER150 |
| site_id | DC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL F 160 |
| Chain | Residue |
| F | LEU88 |
| F | LEU89 |
| F | LYS90 |
| F | ALA91 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO F 161 |
| Chain | Residue |
| F | ALA99 |
| F | THR100 |
| F | HOH523 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO F 162 |
| Chain | Residue |
| F | LEU42 |
| F | ASP51 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG F 163 |
| Chain | Residue |
| F | LEU77 |
| G | LEU77 |
| site_id | DC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP G 158 |
| Chain | Residue |
| C | VAL14 |
| C | CYS74 |
| C | HIS75 |
| C | THR107 |
| C | FLC159 |
| F | SER150 |
| F | GLY151 |
| G | VAL47 |
| G | GLY48 |
| G | LYS49 |
| G | ASP126 |
| G | LYS129 |
| G | ALA130 |
| G | HOH248 |
| G | HOH263 |
| G | HOH264 |
| G | HOH454 |
| site_id | DC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FLC G 159 |
| Chain | Residue |
| C | LYS133 |
| G | ARG24 |
| G | GLY108 |
| G | GLU110 |
| G | LYS145 |
| G | LYS149 |
| G | SER150 |
| G | HOH458 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO G 160 |
| Chain | Residue |
| G | ARG85 |
| G | GLU98 |
| G | THR100 |
| site_id | DC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO G 161 |
| Chain | Residue |
| G | ALA64 |
| G | LYS65 |
| G | LYS66 |
| G | THR67 |
| G | ALA68 |
| G | PRO76 |
| G | LEU77 |
| G | GLU112 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO G 162 |
| Chain | Residue |
| G | ARG141 |
| G | ARG155 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO G 163 |
| Chain | Residue |
| G | LYS66 |
| G | ASP69 |
| I | ASP69 |
| site_id | EC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GTP H 158 |
| Chain | Residue |
| G | GLY148 |
| H | VAL47 |
| H | LYS49 |
| H | ASP126 |
| H | LYS129 |
| H | ALA130 |
| I | VAL14 |
| I | CYS74 |
| I | HIS75 |
| I | THR107 |
| I | GLY108 |
| I | MET111 |
| I | FLC159 |
| I | HOH367 |
| site_id | EC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FLC H 159 |
| Chain | Residue |
| H | ARG24 |
| H | GLY108 |
| H | GLU110 |
| H | LYS145 |
| H | GLY148 |
| H | LYS149 |
| H | SER150 |
| I | LYS133 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL H 160 |
| Chain | Residue |
| H | LEU53 |
| H | VAL54 |
| H | GLN57 |
| H | ARG85 |
| H | VAL86 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 161 |
| Chain | Residue |
| C | ARG10 |
| H | GLU83 |
| H | ARG85 |
| H | GLU98 |
| H | ALA99 |
| H | THR100 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO H 162 |
| Chain | Residue |
| H | LEU42 |
| H | ASP51 |
| H | LEU53 |
| H | HOH485 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG H 163 |
| Chain | Residue |
| H | ALA64 |
| H | LYS65 |
| H | ALA68 |
| H | PRO76 |
| H | LEU77 |
| H | GLU112 |
| site_id | EC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GTP I 158 |
| Chain | Residue |
| A | GLU18 |
| H | VAL14 |
| H | CYS74 |
| H | HIS75 |
| H | THR107 |
| I | VAL47 |
| I | GLY48 |
| I | LYS49 |
| I | ASP126 |
| I | LYS129 |
| I | ALA130 |
| I | HOH611 |
| site_id | FC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FLC I 159 |
| Chain | Residue |
| H | GTP158 |
| I | ARG24 |
| I | THR107 |
| I | GLY108 |
| I | LYS145 |
| I | GLY147 |
| I | LYS149 |
| I | SER150 |
| I | HOH367 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO I 160 |
| Chain | Residue |
| C | ALA91 |
| I | GLU83 |
| I | GLU98 |
| I | THR100 |
| site_id | FC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO I 161 |
| Chain | Residue |
| I | LEU42 |
| I | GLY45 |
| I | ASP51 |
| I | HOH488 |
