Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAP A 269 |
| Chain | Residue |
| A | LYS13 |
| A | LEU63 |
| A | THR64 |
| A | ASN93 |
| A | ALA94 |
| A | SER95 |
| A | THR126 |
| A | LEU159 |
| A | CYS160 |
| A | TYR174 |
| A | LYS178 |
| A | ARG14 |
| A | PRO204 |
| A | GLY205 |
| A | SER207 |
| A | LEU208 |
| A | AX2270 |
| A | D1D272 |
| A | HOH288 |
| A | HOH289 |
| A | HOH306 |
| A | HOH308 |
| A | ILE15 |
| A | HOH320 |
| A | HOH322 |
| A | HOH323 |
| A | HOH334 |
| A | HOH380 |
| A | HOH391 |
| A | TYR34 |
| A | HIS35 |
| A | ASN36 |
| A | SER37 |
| A | ALA61 |
| A | ASP62 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AX2 A 270 |
| Chain | Residue |
| A | ARG14 |
| A | SER95 |
| A | PHE97 |
| A | ASP161 |
| A | TYR174 |
| A | NAP269 |
| A | D1D272 |
| A | HOH306 |
| A | HOH308 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DTT A 271 |
| Chain | Residue |
| A | CYS168 |
| A | PHE171 |
| A | GLU217 |
| A | TRP221 |
| A | D1D272 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE D1D A 272 |
| Chain | Residue |
| A | PHE97 |
| A | TRP221 |
| A | NAP269 |
| A | AX2270 |
| A | DTT271 |
| A | HOH331 |
| A | HOH357 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 273 |
| Chain | Residue |
| A | LYS13 |
| A | ARG14 |
| A | ARG17 |
| A | HOH397 |
| A | HOH398 |
| A | HOH400 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 274 |
| Chain | Residue |
| A | GLN186 |
| A | GLY254 |
| A | ILE256 |
| A | HOH312 |
| A | HOH393 |
| A | HOH413 |
| B | LYS258 |
| B | HOH495 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 275 |
| Chain | Residue |
| A | LYS258 |
| A | HOH303 |
| A | HOH354 |
| A | HOH509 |
| B | GLN186 |
| B | GLY254 |
| B | ILE256 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 277 |
| Chain | Residue |
| A | LEU208 |
| A | ARG230 |
| A | GLU231 |
| A | HOH511 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DTT A 276 |
| Chain | Residue |
| A | GLU215 |
| A | LYS218 |
| A | ARG222 |
| A | HOH512 |
| site_id | BC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE NAP B 269 |
| Chain | Residue |
| B | LEU159 |
| B | CYS160 |
| B | TYR174 |
| B | LYS178 |
| B | PRO204 |
| B | GLY205 |
| B | SER207 |
| B | LEU208 |
| B | AX2270 |
| B | D1D272 |
| B | HOH420 |
| B | HOH425 |
| B | HOH441 |
| B | HOH450 |
| B | HOH471 |
| B | HOH477 |
| B | HOH492 |
| B | HOH501 |
| B | HOH516 |
| B | HOH631 |
| B | ARG14 |
| B | ILE15 |
| B | TYR34 |
| B | HIS35 |
| B | ASN36 |
| B | SER37 |
| B | ALA61 |
| B | ASP62 |
| B | LEU63 |
| B | THR64 |
| B | ASN93 |
| B | ALA94 |
| B | SER95 |
| B | THR126 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AX2 B 270 |
| Chain | Residue |
| B | ARG14 |
| B | SER95 |
| B | PHE97 |
| B | ASP161 |
| B | TYR174 |
| B | NAP269 |
| B | D1D272 |
| B | HOH465 |
| B | HOH492 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DTT B 271 |
| Chain | Residue |
| B | CYS168 |
| B | TRP221 |
| B | D1D272 |
| B | HOH616 |
| B | HOH633 |
| B | HOH645 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE D1D B 272 |
| Chain | Residue |
| B | TRP221 |
| B | NAP269 |
| B | AX2270 |
| B | DTT271 |
| B | HOH443 |
| B | HOH465 |
| B | HOH482 |
| B | HOH633 |
| site_id | BC5 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE NAP C 269 |
| Chain | Residue |
| C | ARG14 |
| C | ILE15 |
| C | HIS33 |
| C | TYR34 |
| C | HIS35 |
| C | ASN36 |
| C | SER37 |
| C | ALA61 |
| C | ASP62 |
| C | LEU63 |
| C | THR64 |
| C | ASN93 |
| C | ALA94 |
| C | SER95 |
| C | THR126 |
| C | LEU159 |
| C | CYS160 |
| C | ASP161 |
| C | TYR174 |
| C | LYS178 |
| C | PRO204 |
| C | GLY205 |
| C | VAL206 |
| C | SER207 |
| C | LEU208 |
| C | D1D270 |
| C | AX2272 |
| C | HOH408 |
| C | HOH414 |
| C | HOH425 |
| C | HOH437 |
| C | HOH447 |
| C | HOH460 |
| C | HOH461 |
| C | HOH494 |
| C | HOH587 |
| C | HOH595 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AX2 C 272 |
| Chain | Residue |
| C | ARG14 |
| C | SER95 |
| C | PHE97 |
| C | ASP161 |
| C | TYR174 |
| C | NAP269 |
| C | D1D270 |
| C | HOH437 |
| C | HOH461 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DTT C 273 |
| Chain | Residue |
| C | CYS168 |
| C | GLU217 |
| C | TRP221 |
| C | D1D270 |
| C | HOH582 |
| C | HOH593 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE D1D C 270 |
| Chain | Residue |
| C | ASP161 |
| C | TRP221 |
| C | NAP269 |
| C | AX2272 |
| C | DTT273 |
| C | HOH432 |
| C | HOH486 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT C 271 |
| Chain | Residue |
| B | TYR34 |
| B | VAL58 |
| B | HOH560 |
| C | VAL57 |
| C | VAL58 |
| C | HOH536 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 274 |
| Chain | Residue |
| C | LYS258 |
| C | HOH438 |
| C | HOH469 |
| C | HOH516 |
| D | GLN186 |
| D | GLY254 |
| D | ILE256 |
| site_id | CC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL C 275 |
| Chain | Residue |
| B | ASP46 |
| B | ALA56 |
| B | VAL57 |
| B | VAL58 |
| C | TYR34 |
| C | VAL58 |
| C | GLN60 |
| C | ARG82 |
| C | HOH536 |
| C | HOH613 |
| C | HOH643 |
| site_id | CC3 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAP D 269 |
| Chain | Residue |
| D | ARG14 |
| D | ILE15 |
| D | TYR34 |
| D | HIS35 |
| D | ASN36 |
| D | SER37 |
| D | ALA61 |
| D | ASP62 |
| D | LEU63 |
| D | THR64 |
| D | ASN93 |
| D | ALA94 |
| D | SER95 |
| D | THR126 |
| D | LEU159 |
| D | CYS160 |
| D | TYR174 |
| D | LYS178 |
| D | PRO204 |
| D | GLY205 |
| D | SER207 |
| D | LEU208 |
| D | AX2270 |
| D | D1D272 |
| D | HOH447 |
| D | HOH449 |
| D | HOH460 |
| D | HOH471 |
| D | HOH475 |
| D | HOH490 |
| D | HOH509 |
| D | HOH513 |
| D | HOH523 |
| D | HOH532 |
| D | HOH658 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AX2 D 270 |
| Chain | Residue |
| D | ARG14 |
| D | SER95 |
| D | PHE97 |
| D | ASP161 |
| D | TYR174 |
| D | NAP269 |
| D | D1D272 |
| D | HOH490 |
| D | HOH513 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DTT D 271 |
| Chain | Residue |
| D | CYS168 |
| D | MET213 |
| D | TRP221 |
| D | D1D272 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE D1D D 272 |
| Chain | Residue |
| D | VAL206 |
| D | TRP221 |
| D | NAP269 |
| D | AX2270 |
| D | DTT271 |
| D | HOH477 |
| D | HOH490 |
| D | HOH510 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT D 273 |
| Chain | Residue |
| C | GLN186 |
| C | GLY254 |
| C | ILE256 |
| D | LYS258 |
| D | HOH482 |
| D | HOH504 |
| D | HOH561 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. DamvdqpcmaFslYNMGKHALvGLTqSAA |
| Chain | Residue | Details |
| C | ASP161-ALA189 | |
| A | ASP161-ALA189 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | ASP165 | |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | PHE171 | |
| B | LYS178 | |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | PHE171 | |
| D | LYS178 | |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | PHE171 | |
| C | LYS178 | |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | TYR174 | |
| A | LYS178 | |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | TYR174 | |
| D | LYS178 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | ASP165 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | ASP165 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | ASP165 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | SER152 | |
| A | TYR174 | |
| A | LYS178 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | TYR174 | |
| B | LYS178 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | SER152 | |
| D | TYR174 | |
| D | LYS178 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | TYR174 | |
| C | LYS178 | |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | PHE171 | |
| A | LYS178 | |
