3J2I

Structure of late pre-60S ribosomal subunits with nuclear export factor Arx1 bound at the peptide exit tunnel

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003714	molecular_function	transcription corepressor activity
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006364	biological_process	rRNA processing
A	0006417	biological_process	regulation of translation
A	0016020	cellular_component	membrane
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0035578	cellular_component	azurophil granule lumen
A	0043066	biological_process	negative regulation of apoptotic process
A	0045597	biological_process	positive regulation of cell differentiation
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0070062	cellular_component	extracellular exosome
A	1990904	cellular_component	ribonucleoprotein complex
B	0000054	biological_process	ribosomal subunit export from nucleus
B	0000460	biological_process	maturation of 5.8S rRNA
B	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000470	biological_process	maturation of LSU-rRNA
B	0003743	molecular_function	translation initiation factor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006364	biological_process	rRNA processing
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0030687	cellular_component	preribosome, large subunit precursor
B	0042254	biological_process	ribosome biogenesis
B	0042256	biological_process	cytosolic ribosome assembly
B	0042273	biological_process	ribosomal large subunit biogenesis
B	0043022	molecular_function	ribosome binding
B	0043023	molecular_function	ribosomal large subunit binding
B	1902626	biological_process	assembly of large subunit precursor of preribosome

Functional Information from PROSITE/UniProt

site_id	PS01202
Number of Residues	17
Details	MAP_2 Methionine aminopeptidase subfamily 2 signature. DLvKIDlGvHVDGfiaN

Chain	Residue	Details
A	ASP104-ASN120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by CK1","evidences":[{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"RNA-binding","evidences":[{"source":"PubMed","id":"15064750","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC/PRKCD","evidences":[{"source":"PubMed","id":"16832058","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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