3J0S

Remodeling of actin filaments by ADF cofilin proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0005886	cellular_component	plasma membrane
A	0005925	cellular_component	focal adhesion
A	0007409	biological_process	axonogenesis
A	0015629	cellular_component	actin cytoskeleton
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019901	molecular_function	protein kinase binding
A	0030027	cellular_component	lamellipodium
A	0030424	cellular_component	axon
A	0035267	cellular_component	NuA4 histone acetyltransferase complex
A	0045202	cellular_component	synapse
A	0048870	biological_process	cell motility
A	0097433	cellular_component	dense body
A	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
A	0098974	biological_process	postsynaptic actin cytoskeleton organization
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005884	cellular_component	actin filament
B	0005886	cellular_component	plasma membrane
B	0005925	cellular_component	focal adhesion
B	0007409	biological_process	axonogenesis
B	0015629	cellular_component	actin cytoskeleton
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0019901	molecular_function	protein kinase binding
B	0030027	cellular_component	lamellipodium
B	0030424	cellular_component	axon
B	0035267	cellular_component	NuA4 histone acetyltransferase complex
B	0045202	cellular_component	synapse
B	0048870	biological_process	cell motility
B	0097433	cellular_component	dense body
B	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
B	0098974	biological_process	postsynaptic actin cytoskeleton organization
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005856	cellular_component	cytoskeleton
C	0005884	cellular_component	actin filament
C	0005886	cellular_component	plasma membrane
C	0005925	cellular_component	focal adhesion
C	0007409	biological_process	axonogenesis
C	0015629	cellular_component	actin cytoskeleton
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0019901	molecular_function	protein kinase binding
C	0030027	cellular_component	lamellipodium
C	0030424	cellular_component	axon
C	0035267	cellular_component	NuA4 histone acetyltransferase complex
C	0045202	cellular_component	synapse
C	0048870	biological_process	cell motility
C	0097433	cellular_component	dense body
C	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
C	0098974	biological_process	postsynaptic actin cytoskeleton organization
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005884	cellular_component	actin filament
D	0005886	cellular_component	plasma membrane
D	0005925	cellular_component	focal adhesion
D	0007409	biological_process	axonogenesis
D	0015629	cellular_component	actin cytoskeleton
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0019901	molecular_function	protein kinase binding
D	0030027	cellular_component	lamellipodium
D	0030424	cellular_component	axon
D	0035267	cellular_component	NuA4 histone acetyltransferase complex
D	0045202	cellular_component	synapse
D	0048870	biological_process	cell motility
D	0097433	cellular_component	dense body
D	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
D	0098974	biological_process	postsynaptic actin cytoskeleton organization
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005884	cellular_component	actin filament
E	0005886	cellular_component	plasma membrane
E	0005925	cellular_component	focal adhesion
E	0007409	biological_process	axonogenesis
E	0015629	cellular_component	actin cytoskeleton
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0019901	molecular_function	protein kinase binding
E	0030027	cellular_component	lamellipodium
E	0030424	cellular_component	axon
E	0035267	cellular_component	NuA4 histone acetyltransferase complex
E	0045202	cellular_component	synapse
E	0048870	biological_process	cell motility
E	0097433	cellular_component	dense body
E	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
E	0098974	biological_process	postsynaptic actin cytoskeleton organization
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005884	cellular_component	actin filament
F	0005886	cellular_component	plasma membrane
F	0005925	cellular_component	focal adhesion
F	0007409	biological_process	axonogenesis
F	0015629	cellular_component	actin cytoskeleton
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0019901	molecular_function	protein kinase binding
F	0030027	cellular_component	lamellipodium
F	0030424	cellular_component	axon
F	0035267	cellular_component	NuA4 histone acetyltransferase complex
F	0045202	cellular_component	synapse
F	0048870	biological_process	cell motility
F	0097433	cellular_component	dense body
F	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
F	0098974	biological_process	postsynaptic actin cytoskeleton organization
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005856	cellular_component	cytoskeleton
G	0005884	cellular_component	actin filament
G	0005886	cellular_component	plasma membrane
G	0005925	cellular_component	focal adhesion
G	0007409	biological_process	axonogenesis
G	0015629	cellular_component	actin cytoskeleton
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0019901	molecular_function	protein kinase binding
G	0030027	cellular_component	lamellipodium
G	0030424	cellular_component	axon
G	0035267	cellular_component	NuA4 histone acetyltransferase complex
G	0045202	cellular_component	synapse
G	0048870	biological_process	cell motility
G	0097433	cellular_component	dense body
G	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
G	0098974	biological_process	postsynaptic actin cytoskeleton organization
H	0000166	molecular_function	nucleotide binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005856	cellular_component	cytoskeleton
H	0005884	cellular_component	actin filament
H	0005886	cellular_component	plasma membrane
H	0005925	cellular_component	focal adhesion
H	0007409	biological_process	axonogenesis
H	0015629	cellular_component	actin cytoskeleton
H	0016020	cellular_component	membrane
H	0016787	molecular_function	hydrolase activity
H	0019901	molecular_function	protein kinase binding
H	0030027	cellular_component	lamellipodium
H	0030424	cellular_component	axon
H	0035267	cellular_component	NuA4 histone acetyltransferase complex
H	0045202	cellular_component	synapse
H	0048870	biological_process	cell motility
H	0097433	cellular_component	dense body
H	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
H	0098974	biological_process	postsynaptic actin cytoskeleton organization
I	0000166	molecular_function	nucleotide binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005737	cellular_component	cytoplasm
I	0005856	cellular_component	cytoskeleton
I	0005884	cellular_component	actin filament
I	0005886	cellular_component	plasma membrane
I	0005925	cellular_component	focal adhesion
I	0007409	biological_process	axonogenesis
I	0015629	cellular_component	actin cytoskeleton
I	0016020	cellular_component	membrane
I	0016787	molecular_function	hydrolase activity
I	0019901	molecular_function	protein kinase binding
I	0030027	cellular_component	lamellipodium
I	0030424	cellular_component	axon
I	0035267	cellular_component	NuA4 histone acetyltransferase complex
I	0045202	cellular_component	synapse
I	0048870	biological_process	cell motility
I	0097433	cellular_component	dense body
I	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
I	0098974	biological_process	postsynaptic actin cytoskeleton organization
J	0000166	molecular_function	nucleotide binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005856	cellular_component	cytoskeleton
J	0005884	cellular_component	actin filament
J	0005886	cellular_component	plasma membrane
J	0005925	cellular_component	focal adhesion
J	0007409	biological_process	axonogenesis
J	0015629	cellular_component	actin cytoskeleton
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0019901	molecular_function	protein kinase binding
J	0030027	cellular_component	lamellipodium
J	0030424	cellular_component	axon
J	0035267	cellular_component	NuA4 histone acetyltransferase complex
J	0045202	cellular_component	synapse
J	0048870	biological_process	cell motility
J	0097433	cellular_component	dense body
J	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
J	0098974	biological_process	postsynaptic actin cytoskeleton organization
K	0000166	molecular_function	nucleotide binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005856	cellular_component	cytoskeleton
K	0005884	cellular_component	actin filament
K	0005886	cellular_component	plasma membrane
K	0005925	cellular_component	focal adhesion
K	0007409	biological_process	axonogenesis
K	0015629	cellular_component	actin cytoskeleton
K	0016020	cellular_component	membrane
K	0016787	molecular_function	hydrolase activity
K	0019901	molecular_function	protein kinase binding
K	0030027	cellular_component	lamellipodium
K	0030424	cellular_component	axon
K	0035267	cellular_component	NuA4 histone acetyltransferase complex
K	0045202	cellular_component	synapse
K	0048870	biological_process	cell motility
K	0097433	cellular_component	dense body
K	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
K	0098974	biological_process	postsynaptic actin cytoskeleton organization
L	0000166	molecular_function	nucleotide binding
L	0005524	molecular_function	ATP binding
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005856	cellular_component	cytoskeleton
L	0005884	cellular_component	actin filament
L	0005886	cellular_component	plasma membrane
L	0005925	cellular_component	focal adhesion
L	0007409	biological_process	axonogenesis
L	0015629	cellular_component	actin cytoskeleton
L	0016020	cellular_component	membrane
L	0016787	molecular_function	hydrolase activity
L	0019901	molecular_function	protein kinase binding
L	0030027	cellular_component	lamellipodium
L	0030424	cellular_component	axon
L	0035267	cellular_component	NuA4 histone acetyltransferase complex
L	0045202	cellular_component	synapse
L	0048870	biological_process	cell motility
L	0097433	cellular_component	dense body
L	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
L	0098974	biological_process	postsynaptic actin cytoskeleton organization
M	0000281	biological_process	mitotic cytokinesis
M	0001755	biological_process	neural crest cell migration
M	0001842	biological_process	neural fold formation
M	0003779	molecular_function	actin binding
M	0005102	molecular_function	signaling receptor binding
M	0005515	molecular_function	protein binding
M	0005615	cellular_component	extracellular space
M	0005634	cellular_component	nucleus
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005856	cellular_component	cytoskeleton
M	0005886	cellular_component	plasma membrane
M	0005911	cellular_component	cell-cell junction
M	0005925	cellular_component	focal adhesion
M	0006606	biological_process	protein import into nucleus
M	0007010	biological_process	cytoskeleton organization
M	0007015	biological_process	actin filament organization
M	0007162	biological_process	negative regulation of cell adhesion
M	0007266	biological_process	Rho protein signal transduction
M	0008154	biological_process	actin polymerization or depolymerization
M	0009615	biological_process	response to virus
M	0010592	biological_process	positive regulation of lamellipodium assembly
M	0010593	biological_process	negative regulation of lamellipodium assembly
M	0014823	biological_process	response to activity
M	0015629	cellular_component	actin cytoskeleton
M	0016020	cellular_component	membrane
M	0016363	cellular_component	nuclear matrix
M	0019903	molecular_function	protein phosphatase binding
M	0021766	biological_process	hippocampus development
M	0022604	biological_process	regulation of cell morphogenesis
M	0030010	biological_process	establishment of cell polarity
M	0030027	cellular_component	lamellipodium
M	0030030	biological_process	cell projection organization
M	0030036	biological_process	actin cytoskeleton organization
M	0030042	biological_process	actin filament depolymerization
M	0030043	biological_process	actin filament fragmentation
M	0030175	cellular_component	filopodium
M	0030307	biological_process	positive regulation of cell growth
M	0030424	cellular_component	axon
M	0030426	cellular_component	growth cone
M	0030835	biological_process	negative regulation of actin filament depolymerization
M	0030836	biological_process	positive regulation of actin filament depolymerization
M	0030864	cellular_component	cortical actin cytoskeleton
M	0031252	cellular_component	cell leading edge
M	0031258	cellular_component	lamellipodium membrane
M	0031915	biological_process	positive regulation of synaptic plasticity
M	0031966	cellular_component	mitochondrial membrane
M	0031982	cellular_component	vesicle
M	0032232	biological_process	negative regulation of actin filament bundle assembly
M	0032587	cellular_component	ruffle membrane
M	0040019	biological_process	positive regulation of embryonic development
M	0042995	cellular_component	cell projection
M	0043025	cellular_component	neuronal cell body
M	0043066	biological_process	negative regulation of apoptotic process
M	0043197	cellular_component	dendritic spine
M	0043200	biological_process	response to amino acid
M	0044794	biological_process	host-mediated activation of viral process
M	0045792	biological_process	negative regulation of cell size
M	0045862	biological_process	positive regulation of proteolysis
M	0048870	biological_process	cell motility
M	0050804	biological_process	modulation of chemical synaptic transmission
M	0051014	biological_process	actin filament severing
M	0051015	molecular_function	actin filament binding
M	0051293	biological_process	establishment of spindle localization
M	0051511	biological_process	negative regulation of unidimensional cell growth
M	0051894	biological_process	positive regulation of focal adhesion assembly
M	0060999	biological_process	positive regulation of dendritic spine development
M	0061001	biological_process	regulation of dendritic spine morphogenesis
M	0070062	cellular_component	extracellular exosome
M	0070301	biological_process	cellular response to hydrogen peroxide
M	0071347	biological_process	cellular response to interleukin-1
M	0071354	biological_process	cellular response to interleukin-6
M	0071356	biological_process	cellular response to tumor necrosis factor
M	0071362	biological_process	cellular response to ether
M	0071364	biological_process	cellular response to epidermal growth factor stimulus
M	0090732	cellular_component	cofilin-actin rod
M	0097060	cellular_component	synaptic membrane
M	0098885	biological_process	modification of postsynaptic actin cytoskeleton
M	0098978	cellular_component	glutamatergic synapse
M	0099092	cellular_component	postsynaptic density, intracellular component
M	1902936	molecular_function	phosphatidylinositol bisphosphate binding
M	1902951	biological_process	negative regulation of dendritic spine maintenance
M	1905873	biological_process	positive regulation of protein localization to cell leading edge
M	1905875	biological_process	negative regulation of postsynaptic density organization
M	1990314	biological_process	cellular response to insulin-like growth factor stimulus
M	2000146	biological_process	negative regulation of cell motility
M	2000147	biological_process	positive regulation of cell motility
M	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
M	2000814	biological_process	positive regulation of barbed-end actin filament capping
N	0000281	biological_process	mitotic cytokinesis
N	0001755	biological_process	neural crest cell migration
N	0001842	biological_process	neural fold formation
N	0003779	molecular_function	actin binding
N	0005102	molecular_function	signaling receptor binding
N	0005515	molecular_function	protein binding
N	0005615	cellular_component	extracellular space
N	0005634	cellular_component	nucleus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005856	cellular_component	cytoskeleton
N	0005886	cellular_component	plasma membrane
N	0005911	cellular_component	cell-cell junction
N	0005925	cellular_component	focal adhesion
N	0006606	biological_process	protein import into nucleus
N	0007010	biological_process	cytoskeleton organization
N	0007015	biological_process	actin filament organization
N	0007162	biological_process	negative regulation of cell adhesion
N	0007266	biological_process	Rho protein signal transduction
N	0008154	biological_process	actin polymerization or depolymerization
N	0009615	biological_process	response to virus
N	0010592	biological_process	positive regulation of lamellipodium assembly
N	0010593	biological_process	negative regulation of lamellipodium assembly
N	0014823	biological_process	response to activity
N	0015629	cellular_component	actin cytoskeleton
N	0016020	cellular_component	membrane
N	0016363	cellular_component	nuclear matrix
N	0019903	molecular_function	protein phosphatase binding
N	0021766	biological_process	hippocampus development
N	0022604	biological_process	regulation of cell morphogenesis
N	0030010	biological_process	establishment of cell polarity
N	0030027	cellular_component	lamellipodium
N	0030030	biological_process	cell projection organization
N	0030036	biological_process	actin cytoskeleton organization
N	0030042	biological_process	actin filament depolymerization
N	0030043	biological_process	actin filament fragmentation
N	0030175	cellular_component	filopodium
N	0030307	biological_process	positive regulation of cell growth
N	0030424	cellular_component	axon
N	0030426	cellular_component	growth cone
N	0030835	biological_process	negative regulation of actin filament depolymerization
N	0030836	biological_process	positive regulation of actin filament depolymerization
N	0030864	cellular_component	cortical actin cytoskeleton
N	0031252	cellular_component	cell leading edge
N	0031258	cellular_component	lamellipodium membrane
N	0031915	biological_process	positive regulation of synaptic plasticity
N	0031966	cellular_component	mitochondrial membrane
N	0031982	cellular_component	vesicle
N	0032232	biological_process	negative regulation of actin filament bundle assembly
N	0032587	cellular_component	ruffle membrane
N	0040019	biological_process	positive regulation of embryonic development
N	0042995	cellular_component	cell projection
N	0043025	cellular_component	neuronal cell body
N	0043066	biological_process	negative regulation of apoptotic process
N	0043197	cellular_component	dendritic spine
N	0043200	biological_process	response to amino acid
N	0044794	biological_process	host-mediated activation of viral process
N	0045792	biological_process	negative regulation of cell size
N	0045862	biological_process	positive regulation of proteolysis
N	0048870	biological_process	cell motility
N	0050804	biological_process	modulation of chemical synaptic transmission
N	0051014	biological_process	actin filament severing
N	0051015	molecular_function	actin filament binding
N	0051293	biological_process	establishment of spindle localization
N	0051511	biological_process	negative regulation of unidimensional cell growth
N	0051894	biological_process	positive regulation of focal adhesion assembly
N	0060999	biological_process	positive regulation of dendritic spine development
N	0061001	biological_process	regulation of dendritic spine morphogenesis
N	0070062	cellular_component	extracellular exosome
N	0070301	biological_process	cellular response to hydrogen peroxide
N	0071347	biological_process	cellular response to interleukin-1
N	0071354	biological_process	cellular response to interleukin-6
N	0071356	biological_process	cellular response to tumor necrosis factor
N	0071362	biological_process	cellular response to ether
N	0071364	biological_process	cellular response to epidermal growth factor stimulus
N	0090732	cellular_component	cofilin-actin rod
N	0097060	cellular_component	synaptic membrane
N	0098885	biological_process	modification of postsynaptic actin cytoskeleton
N	0098978	cellular_component	glutamatergic synapse
N	0099092	cellular_component	postsynaptic density, intracellular component
N	1902936	molecular_function	phosphatidylinositol bisphosphate binding
N	1902951	biological_process	negative regulation of dendritic spine maintenance
N	1905873	biological_process	positive regulation of protein localization to cell leading edge
N	1905875	biological_process	negative regulation of postsynaptic density organization
N	1990314	biological_process	cellular response to insulin-like growth factor stimulus
N	2000146	biological_process	negative regulation of cell motility
N	2000147	biological_process	positive regulation of cell motility
N	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
N	2000814	biological_process	positive regulation of barbed-end actin filament capping
O	0000281	biological_process	mitotic cytokinesis
O	0001755	biological_process	neural crest cell migration
O	0001842	biological_process	neural fold formation
O	0003779	molecular_function	actin binding
O	0005102	molecular_function	signaling receptor binding
O	0005515	molecular_function	protein binding
O	0005615	cellular_component	extracellular space
O	0005634	cellular_component	nucleus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005856	cellular_component	cytoskeleton
O	0005886	cellular_component	plasma membrane
O	0005911	cellular_component	cell-cell junction
O	0005925	cellular_component	focal adhesion
O	0006606	biological_process	protein import into nucleus
O	0007010	biological_process	cytoskeleton organization
O	0007015	biological_process	actin filament organization
O	0007162	biological_process	negative regulation of cell adhesion
O	0007266	biological_process	Rho protein signal transduction
O	0008154	biological_process	actin polymerization or depolymerization
O	0009615	biological_process	response to virus
O	0010592	biological_process	positive regulation of lamellipodium assembly
O	0010593	biological_process	negative regulation of lamellipodium assembly
O	0014823	biological_process	response to activity
O	0015629	cellular_component	actin cytoskeleton
O	0016020	cellular_component	membrane
O	0016363	cellular_component	nuclear matrix
O	0019903	molecular_function	protein phosphatase binding
O	0021766	biological_process	hippocampus development
O	0022604	biological_process	regulation of cell morphogenesis
O	0030010	biological_process	establishment of cell polarity
O	0030027	cellular_component	lamellipodium
O	0030030	biological_process	cell projection organization
O	0030036	biological_process	actin cytoskeleton organization
O	0030042	biological_process	actin filament depolymerization
O	0030043	biological_process	actin filament fragmentation
O	0030175	cellular_component	filopodium
O	0030307	biological_process	positive regulation of cell growth
O	0030424	cellular_component	axon
O	0030426	cellular_component	growth cone
O	0030835	biological_process	negative regulation of actin filament depolymerization
O	0030836	biological_process	positive regulation of actin filament depolymerization
O	0030864	cellular_component	cortical actin cytoskeleton
O	0031252	cellular_component	cell leading edge
O	0031258	cellular_component	lamellipodium membrane
O	0031915	biological_process	positive regulation of synaptic plasticity
O	0031966	cellular_component	mitochondrial membrane
O	0031982	cellular_component	vesicle
O	0032232	biological_process	negative regulation of actin filament bundle assembly
O	0032587	cellular_component	ruffle membrane
O	0040019	biological_process	positive regulation of embryonic development
O	0042995	cellular_component	cell projection
O	0043025	cellular_component	neuronal cell body
O	0043066	biological_process	negative regulation of apoptotic process
O	0043197	cellular_component	dendritic spine
O	0043200	biological_process	response to amino acid
O	0044794	biological_process	host-mediated activation of viral process
O	0045792	biological_process	negative regulation of cell size
O	0045862	biological_process	positive regulation of proteolysis
O	0048870	biological_process	cell motility
O	0050804	biological_process	modulation of chemical synaptic transmission
O	0051014	biological_process	actin filament severing
O	0051015	molecular_function	actin filament binding
O	0051293	biological_process	establishment of spindle localization
O	0051511	biological_process	negative regulation of unidimensional cell growth
O	0051894	biological_process	positive regulation of focal adhesion assembly
O	0060999	biological_process	positive regulation of dendritic spine development
O	0061001	biological_process	regulation of dendritic spine morphogenesis
O	0070062	cellular_component	extracellular exosome
O	0070301	biological_process	cellular response to hydrogen peroxide
O	0071347	biological_process	cellular response to interleukin-1
O	0071354	biological_process	cellular response to interleukin-6
O	0071356	biological_process	cellular response to tumor necrosis factor
O	0071362	biological_process	cellular response to ether
O	0071364	biological_process	cellular response to epidermal growth factor stimulus
O	0090732	cellular_component	cofilin-actin rod
O	0097060	cellular_component	synaptic membrane
O	0098885	biological_process	modification of postsynaptic actin cytoskeleton
O	0098978	cellular_component	glutamatergic synapse
O	0099092	cellular_component	postsynaptic density, intracellular component
O	1902936	molecular_function	phosphatidylinositol bisphosphate binding
O	1902951	biological_process	negative regulation of dendritic spine maintenance
O	1905873	biological_process	positive regulation of protein localization to cell leading edge
O	1905875	biological_process	negative regulation of postsynaptic density organization
O	1990314	biological_process	cellular response to insulin-like growth factor stimulus
O	2000146	biological_process	negative regulation of cell motility
O	2000147	biological_process	positive regulation of cell motility
O	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
O	2000814	biological_process	positive regulation of barbed-end actin filament capping
P	0000281	biological_process	mitotic cytokinesis
P	0001755	biological_process	neural crest cell migration
P	0001842	biological_process	neural fold formation
P	0003779	molecular_function	actin binding
P	0005102	molecular_function	signaling receptor binding
P	0005515	molecular_function	protein binding
P	0005615	cellular_component	extracellular space
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005856	cellular_component	cytoskeleton
P	0005886	cellular_component	plasma membrane
P	0005911	cellular_component	cell-cell junction
P	0005925	cellular_component	focal adhesion
P	0006606	biological_process	protein import into nucleus
P	0007010	biological_process	cytoskeleton organization
P	0007015	biological_process	actin filament organization
P	0007162	biological_process	negative regulation of cell adhesion
P	0007266	biological_process	Rho protein signal transduction
P	0008154	biological_process	actin polymerization or depolymerization
P	0009615	biological_process	response to virus
P	0010592	biological_process	positive regulation of lamellipodium assembly
P	0010593	biological_process	negative regulation of lamellipodium assembly
P	0014823	biological_process	response to activity
P	0015629	cellular_component	actin cytoskeleton
P	0016020	cellular_component	membrane
P	0016363	cellular_component	nuclear matrix
P	0019903	molecular_function	protein phosphatase binding
P	0021766	biological_process	hippocampus development
P	0022604	biological_process	regulation of cell morphogenesis
P	0030010	biological_process	establishment of cell polarity
P	0030027	cellular_component	lamellipodium
P	0030030	biological_process	cell projection organization
P	0030036	biological_process	actin cytoskeleton organization
P	0030042	biological_process	actin filament depolymerization
P	0030043	biological_process	actin filament fragmentation
P	0030175	cellular_component	filopodium
P	0030307	biological_process	positive regulation of cell growth
P	0030424	cellular_component	axon
P	0030426	cellular_component	growth cone
P	0030835	biological_process	negative regulation of actin filament depolymerization
P	0030836	biological_process	positive regulation of actin filament depolymerization
P	0030864	cellular_component	cortical actin cytoskeleton
P	0031252	cellular_component	cell leading edge
P	0031258	cellular_component	lamellipodium membrane
P	0031915	biological_process	positive regulation of synaptic plasticity
P	0031966	cellular_component	mitochondrial membrane
P	0031982	cellular_component	vesicle
P	0032232	biological_process	negative regulation of actin filament bundle assembly
P	0032587	cellular_component	ruffle membrane
P	0040019	biological_process	positive regulation of embryonic development
P	0042995	cellular_component	cell projection
P	0043025	cellular_component	neuronal cell body
P	0043066	biological_process	negative regulation of apoptotic process
P	0043197	cellular_component	dendritic spine
P	0043200	biological_process	response to amino acid
P	0044794	biological_process	host-mediated activation of viral process
P	0045792	biological_process	negative regulation of cell size
P	0045862	biological_process	positive regulation of proteolysis
P	0048870	biological_process	cell motility
P	0050804	biological_process	modulation of chemical synaptic transmission
P	0051014	biological_process	actin filament severing
P	0051015	molecular_function	actin filament binding
P	0051293	biological_process	establishment of spindle localization
P	0051511	biological_process	negative regulation of unidimensional cell growth
P	0051894	biological_process	positive regulation of focal adhesion assembly
P	0060999	biological_process	positive regulation of dendritic spine development
P	0061001	biological_process	regulation of dendritic spine morphogenesis
P	0070062	cellular_component	extracellular exosome
P	0070301	biological_process	cellular response to hydrogen peroxide
P	0071347	biological_process	cellular response to interleukin-1
P	0071354	biological_process	cellular response to interleukin-6
P	0071356	biological_process	cellular response to tumor necrosis factor
P	0071362	biological_process	cellular response to ether
P	0071364	biological_process	cellular response to epidermal growth factor stimulus
P	0090732	cellular_component	cofilin-actin rod
P	0097060	cellular_component	synaptic membrane
P	0098885	biological_process	modification of postsynaptic actin cytoskeleton
P	0098978	cellular_component	glutamatergic synapse
P	0099092	cellular_component	postsynaptic density, intracellular component
P	1902936	molecular_function	phosphatidylinositol bisphosphate binding
P	1902951	biological_process	negative regulation of dendritic spine maintenance
P	1905873	biological_process	positive regulation of protein localization to cell leading edge
P	1905875	biological_process	negative regulation of postsynaptic density organization
P	1990314	biological_process	cellular response to insulin-like growth factor stimulus
P	2000146	biological_process	negative regulation of cell motility
P	2000147	biological_process	positive regulation of cell motility
P	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
P	2000814	biological_process	positive regulation of barbed-end actin filament capping
Q	0000281	biological_process	mitotic cytokinesis
Q	0001755	biological_process	neural crest cell migration
Q	0001842	biological_process	neural fold formation
Q	0003779	molecular_function	actin binding
Q	0005102	molecular_function	signaling receptor binding
Q	0005515	molecular_function	protein binding
Q	0005615	cellular_component	extracellular space
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005856	cellular_component	cytoskeleton
Q	0005886	cellular_component	plasma membrane
Q	0005911	cellular_component	cell-cell junction
Q	0005925	cellular_component	focal adhesion
Q	0006606	biological_process	protein import into nucleus
Q	0007010	biological_process	cytoskeleton organization
Q	0007015	biological_process	actin filament organization
Q	0007162	biological_process	negative regulation of cell adhesion
Q	0007266	biological_process	Rho protein signal transduction
Q	0008154	biological_process	actin polymerization or depolymerization
Q	0009615	biological_process	response to virus
Q	0010592	biological_process	positive regulation of lamellipodium assembly
Q	0010593	biological_process	negative regulation of lamellipodium assembly
Q	0014823	biological_process	response to activity
Q	0015629	cellular_component	actin cytoskeleton
Q	0016020	cellular_component	membrane
Q	0016363	cellular_component	nuclear matrix
Q	0019903	molecular_function	protein phosphatase binding
Q	0021766	biological_process	hippocampus development
Q	0022604	biological_process	regulation of cell morphogenesis
Q	0030010	biological_process	establishment of cell polarity
Q	0030027	cellular_component	lamellipodium
Q	0030030	biological_process	cell projection organization
Q	0030036	biological_process	actin cytoskeleton organization
Q	0030042	biological_process	actin filament depolymerization
Q	0030043	biological_process	actin filament fragmentation
Q	0030175	cellular_component	filopodium
Q	0030307	biological_process	positive regulation of cell growth
Q	0030424	cellular_component	axon
Q	0030426	cellular_component	growth cone
Q	0030835	biological_process	negative regulation of actin filament depolymerization
Q	0030836	biological_process	positive regulation of actin filament depolymerization
Q	0030864	cellular_component	cortical actin cytoskeleton
Q	0031252	cellular_component	cell leading edge
Q	0031258	cellular_component	lamellipodium membrane
Q	0031915	biological_process	positive regulation of synaptic plasticity
Q	0031966	cellular_component	mitochondrial membrane
Q	0031982	cellular_component	vesicle
Q	0032232	biological_process	negative regulation of actin filament bundle assembly
Q	0032587	cellular_component	ruffle membrane
Q	0040019	biological_process	positive regulation of embryonic development
Q	0042995	cellular_component	cell projection
Q	0043025	cellular_component	neuronal cell body
Q	0043066	biological_process	negative regulation of apoptotic process
Q	0043197	cellular_component	dendritic spine
Q	0043200	biological_process	response to amino acid
Q	0044794	biological_process	host-mediated activation of viral process
Q	0045792	biological_process	negative regulation of cell size
Q	0045862	biological_process	positive regulation of proteolysis
Q	0048870	biological_process	cell motility
Q	0050804	biological_process	modulation of chemical synaptic transmission
Q	0051014	biological_process	actin filament severing
Q	0051015	molecular_function	actin filament binding
Q	0051293	biological_process	establishment of spindle localization
Q	0051511	biological_process	negative regulation of unidimensional cell growth
Q	0051894	biological_process	positive regulation of focal adhesion assembly
Q	0060999	biological_process	positive regulation of dendritic spine development
Q	0061001	biological_process	regulation of dendritic spine morphogenesis
Q	0070062	cellular_component	extracellular exosome
Q	0070301	biological_process	cellular response to hydrogen peroxide
Q	0071347	biological_process	cellular response to interleukin-1
Q	0071354	biological_process	cellular response to interleukin-6
Q	0071356	biological_process	cellular response to tumor necrosis factor
Q	0071362	biological_process	cellular response to ether
Q	0071364	biological_process	cellular response to epidermal growth factor stimulus
Q	0090732	cellular_component	cofilin-actin rod
Q	0097060	cellular_component	synaptic membrane
Q	0098885	biological_process	modification of postsynaptic actin cytoskeleton
Q	0098978	cellular_component	glutamatergic synapse
Q	0099092	cellular_component	postsynaptic density, intracellular component
Q	1902936	molecular_function	phosphatidylinositol bisphosphate binding
Q	1902951	biological_process	negative regulation of dendritic spine maintenance
Q	1905873	biological_process	positive regulation of protein localization to cell leading edge
Q	1905875	biological_process	negative regulation of postsynaptic density organization
Q	1990314	biological_process	cellular response to insulin-like growth factor stimulus
Q	2000146	biological_process	negative regulation of cell motility
Q	2000147	biological_process	positive regulation of cell motility
Q	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
Q	2000814	biological_process	positive regulation of barbed-end actin filament capping
R	0000281	biological_process	mitotic cytokinesis
R	0001755	biological_process	neural crest cell migration
R	0001842	biological_process	neural fold formation
R	0003779	molecular_function	actin binding
R	0005102	molecular_function	signaling receptor binding
R	0005515	molecular_function	protein binding
R	0005615	cellular_component	extracellular space
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005856	cellular_component	cytoskeleton
R	0005886	cellular_component	plasma membrane
R	0005911	cellular_component	cell-cell junction
R	0005925	cellular_component	focal adhesion
R	0006606	biological_process	protein import into nucleus
R	0007010	biological_process	cytoskeleton organization
R	0007015	biological_process	actin filament organization
R	0007162	biological_process	negative regulation of cell adhesion
R	0007266	biological_process	Rho protein signal transduction
R	0008154	biological_process	actin polymerization or depolymerization
R	0009615	biological_process	response to virus
R	0010592	biological_process	positive regulation of lamellipodium assembly
R	0010593	biological_process	negative regulation of lamellipodium assembly
R	0014823	biological_process	response to activity
R	0015629	cellular_component	actin cytoskeleton
R	0016020	cellular_component	membrane
R	0016363	cellular_component	nuclear matrix
R	0019903	molecular_function	protein phosphatase binding
R	0021766	biological_process	hippocampus development
R	0022604	biological_process	regulation of cell morphogenesis
R	0030010	biological_process	establishment of cell polarity
R	0030027	cellular_component	lamellipodium
R	0030030	biological_process	cell projection organization
R	0030036	biological_process	actin cytoskeleton organization
R	0030042	biological_process	actin filament depolymerization
R	0030043	biological_process	actin filament fragmentation
R	0030175	cellular_component	filopodium
R	0030307	biological_process	positive regulation of cell growth
R	0030424	cellular_component	axon
R	0030426	cellular_component	growth cone
R	0030835	biological_process	negative regulation of actin filament depolymerization
R	0030836	biological_process	positive regulation of actin filament depolymerization
R	0030864	cellular_component	cortical actin cytoskeleton
R	0031252	cellular_component	cell leading edge
R	0031258	cellular_component	lamellipodium membrane
R	0031915	biological_process	positive regulation of synaptic plasticity
R	0031966	cellular_component	mitochondrial membrane
R	0031982	cellular_component	vesicle
R	0032232	biological_process	negative regulation of actin filament bundle assembly
R	0032587	cellular_component	ruffle membrane
R	0040019	biological_process	positive regulation of embryonic development
R	0042995	cellular_component	cell projection
R	0043025	cellular_component	neuronal cell body
R	0043066	biological_process	negative regulation of apoptotic process
R	0043197	cellular_component	dendritic spine
R	0043200	biological_process	response to amino acid
R	0044794	biological_process	host-mediated activation of viral process
R	0045792	biological_process	negative regulation of cell size
R	0045862	biological_process	positive regulation of proteolysis
R	0048870	biological_process	cell motility
R	0050804	biological_process	modulation of chemical synaptic transmission
R	0051014	biological_process	actin filament severing
R	0051015	molecular_function	actin filament binding
R	0051293	biological_process	establishment of spindle localization
R	0051511	biological_process	negative regulation of unidimensional cell growth
R	0051894	biological_process	positive regulation of focal adhesion assembly
R	0060999	biological_process	positive regulation of dendritic spine development
R	0061001	biological_process	regulation of dendritic spine morphogenesis
R	0070062	cellular_component	extracellular exosome
R	0070301	biological_process	cellular response to hydrogen peroxide
R	0071347	biological_process	cellular response to interleukin-1
R	0071354	biological_process	cellular response to interleukin-6
R	0071356	biological_process	cellular response to tumor necrosis factor
R	0071362	biological_process	cellular response to ether
R	0071364	biological_process	cellular response to epidermal growth factor stimulus
R	0090732	cellular_component	cofilin-actin rod
R	0097060	cellular_component	synaptic membrane
R	0098885	biological_process	modification of postsynaptic actin cytoskeleton
R	0098978	cellular_component	glutamatergic synapse
R	0099092	cellular_component	postsynaptic density, intracellular component
R	1902936	molecular_function	phosphatidylinositol bisphosphate binding
R	1902951	biological_process	negative regulation of dendritic spine maintenance
R	1905873	biological_process	positive regulation of protein localization to cell leading edge
R	1905875	biological_process	negative regulation of postsynaptic density organization
R	1990314	biological_process	cellular response to insulin-like growth factor stimulus
R	2000146	biological_process	negative regulation of cell motility
R	2000147	biological_process	positive regulation of cell motility
R	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
R	2000814	biological_process	positive regulation of barbed-end actin filament capping
S	0000281	biological_process	mitotic cytokinesis
S	0001755	biological_process	neural crest cell migration
S	0001842	biological_process	neural fold formation
S	0003779	molecular_function	actin binding
S	0005102	molecular_function	signaling receptor binding
S	0005515	molecular_function	protein binding
S	0005615	cellular_component	extracellular space
S	0005634	cellular_component	nucleus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005856	cellular_component	cytoskeleton
S	0005886	cellular_component	plasma membrane
S	0005911	cellular_component	cell-cell junction
S	0005925	cellular_component	focal adhesion
S	0006606	biological_process	protein import into nucleus
S	0007010	biological_process	cytoskeleton organization
S	0007015	biological_process	actin filament organization
S	0007162	biological_process	negative regulation of cell adhesion
S	0007266	biological_process	Rho protein signal transduction
S	0008154	biological_process	actin polymerization or depolymerization
S	0009615	biological_process	response to virus
S	0010592	biological_process	positive regulation of lamellipodium assembly
S	0010593	biological_process	negative regulation of lamellipodium assembly
S	0014823	biological_process	response to activity
S	0015629	cellular_component	actin cytoskeleton
S	0016020	cellular_component	membrane
S	0016363	cellular_component	nuclear matrix
S	0019903	molecular_function	protein phosphatase binding
S	0021766	biological_process	hippocampus development
S	0022604	biological_process	regulation of cell morphogenesis
S	0030010	biological_process	establishment of cell polarity
S	0030027	cellular_component	lamellipodium
S	0030030	biological_process	cell projection organization
S	0030036	biological_process	actin cytoskeleton organization
S	0030042	biological_process	actin filament depolymerization
S	0030043	biological_process	actin filament fragmentation
S	0030175	cellular_component	filopodium
S	0030307	biological_process	positive regulation of cell growth
S	0030424	cellular_component	axon
S	0030426	cellular_component	growth cone
S	0030835	biological_process	negative regulation of actin filament depolymerization
S	0030836	biological_process	positive regulation of actin filament depolymerization
S	0030864	cellular_component	cortical actin cytoskeleton
S	0031252	cellular_component	cell leading edge
S	0031258	cellular_component	lamellipodium membrane
S	0031915	biological_process	positive regulation of synaptic plasticity
S	0031966	cellular_component	mitochondrial membrane
S	0031982	cellular_component	vesicle
S	0032232	biological_process	negative regulation of actin filament bundle assembly
S	0032587	cellular_component	ruffle membrane
S	0040019	biological_process	positive regulation of embryonic development
S	0042995	cellular_component	cell projection
S	0043025	cellular_component	neuronal cell body
S	0043066	biological_process	negative regulation of apoptotic process
S	0043197	cellular_component	dendritic spine
S	0043200	biological_process	response to amino acid
S	0044794	biological_process	host-mediated activation of viral process
S	0045792	biological_process	negative regulation of cell size
S	0045862	biological_process	positive regulation of proteolysis
S	0048870	biological_process	cell motility
S	0050804	biological_process	modulation of chemical synaptic transmission
S	0051014	biological_process	actin filament severing
S	0051015	molecular_function	actin filament binding
S	0051293	biological_process	establishment of spindle localization
S	0051511	biological_process	negative regulation of unidimensional cell growth
S	0051894	biological_process	positive regulation of focal adhesion assembly
S	0060999	biological_process	positive regulation of dendritic spine development
S	0061001	biological_process	regulation of dendritic spine morphogenesis
S	0070062	cellular_component	extracellular exosome
S	0070301	biological_process	cellular response to hydrogen peroxide
S	0071347	biological_process	cellular response to interleukin-1
S	0071354	biological_process	cellular response to interleukin-6
S	0071356	biological_process	cellular response to tumor necrosis factor
S	0071362	biological_process	cellular response to ether
S	0071364	biological_process	cellular response to epidermal growth factor stimulus
S	0090732	cellular_component	cofilin-actin rod
S	0097060	cellular_component	synaptic membrane
S	0098885	biological_process	modification of postsynaptic actin cytoskeleton
S	0098978	cellular_component	glutamatergic synapse
S	0099092	cellular_component	postsynaptic density, intracellular component
S	1902936	molecular_function	phosphatidylinositol bisphosphate binding
S	1902951	biological_process	negative regulation of dendritic spine maintenance
S	1905873	biological_process	positive regulation of protein localization to cell leading edge
S	1905875	biological_process	negative regulation of postsynaptic density organization
S	1990314	biological_process	cellular response to insulin-like growth factor stimulus
S	2000146	biological_process	negative regulation of cell motility
S	2000147	biological_process	positive regulation of cell motility
S	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
S	2000814	biological_process	positive regulation of barbed-end actin filament capping
T	0000281	biological_process	mitotic cytokinesis
T	0001755	biological_process	neural crest cell migration
T	0001842	biological_process	neural fold formation
T	0003779	molecular_function	actin binding
T	0005102	molecular_function	signaling receptor binding
T	0005515	molecular_function	protein binding
T	0005615	cellular_component	extracellular space
T	0005634	cellular_component	nucleus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005856	cellular_component	cytoskeleton
T	0005886	cellular_component	plasma membrane
T	0005911	cellular_component	cell-cell junction
T	0005925	cellular_component	focal adhesion
T	0006606	biological_process	protein import into nucleus
T	0007010	biological_process	cytoskeleton organization
T	0007015	biological_process	actin filament organization
T	0007162	biological_process	negative regulation of cell adhesion
T	0007266	biological_process	Rho protein signal transduction
T	0008154	biological_process	actin polymerization or depolymerization
T	0009615	biological_process	response to virus
T	0010592	biological_process	positive regulation of lamellipodium assembly
T	0010593	biological_process	negative regulation of lamellipodium assembly
T	0014823	biological_process	response to activity
T	0015629	cellular_component	actin cytoskeleton
T	0016020	cellular_component	membrane
T	0016363	cellular_component	nuclear matrix
T	0019903	molecular_function	protein phosphatase binding
T	0021766	biological_process	hippocampus development
T	0022604	biological_process	regulation of cell morphogenesis
T	0030010	biological_process	establishment of cell polarity
T	0030027	cellular_component	lamellipodium
T	0030030	biological_process	cell projection organization
T	0030036	biological_process	actin cytoskeleton organization
T	0030042	biological_process	actin filament depolymerization
T	0030043	biological_process	actin filament fragmentation
T	0030175	cellular_component	filopodium
T	0030307	biological_process	positive regulation of cell growth
T	0030424	cellular_component	axon
T	0030426	cellular_component	growth cone
T	0030835	biological_process	negative regulation of actin filament depolymerization
T	0030836	biological_process	positive regulation of actin filament depolymerization
T	0030864	cellular_component	cortical actin cytoskeleton
T	0031252	cellular_component	cell leading edge
T	0031258	cellular_component	lamellipodium membrane
T	0031915	biological_process	positive regulation of synaptic plasticity
T	0031966	cellular_component	mitochondrial membrane
T	0031982	cellular_component	vesicle
T	0032232	biological_process	negative regulation of actin filament bundle assembly
T	0032587	cellular_component	ruffle membrane
T	0040019	biological_process	positive regulation of embryonic development
T	0042995	cellular_component	cell projection
T	0043025	cellular_component	neuronal cell body
T	0043066	biological_process	negative regulation of apoptotic process
T	0043197	cellular_component	dendritic spine
T	0043200	biological_process	response to amino acid
T	0044794	biological_process	host-mediated activation of viral process
T	0045792	biological_process	negative regulation of cell size
T	0045862	biological_process	positive regulation of proteolysis
T	0048870	biological_process	cell motility
T	0050804	biological_process	modulation of chemical synaptic transmission
T	0051014	biological_process	actin filament severing
T	0051015	molecular_function	actin filament binding
T	0051293	biological_process	establishment of spindle localization
T	0051511	biological_process	negative regulation of unidimensional cell growth
T	0051894	biological_process	positive regulation of focal adhesion assembly
T	0060999	biological_process	positive regulation of dendritic spine development
T	0061001	biological_process	regulation of dendritic spine morphogenesis
T	0070062	cellular_component	extracellular exosome
T	0070301	biological_process	cellular response to hydrogen peroxide
T	0071347	biological_process	cellular response to interleukin-1
T	0071354	biological_process	cellular response to interleukin-6
T	0071356	biological_process	cellular response to tumor necrosis factor
T	0071362	biological_process	cellular response to ether
T	0071364	biological_process	cellular response to epidermal growth factor stimulus
T	0090732	cellular_component	cofilin-actin rod
T	0097060	cellular_component	synaptic membrane
T	0098885	biological_process	modification of postsynaptic actin cytoskeleton
T	0098978	cellular_component	glutamatergic synapse
T	0099092	cellular_component	postsynaptic density, intracellular component
T	1902936	molecular_function	phosphatidylinositol bisphosphate binding
T	1902951	biological_process	negative regulation of dendritic spine maintenance
T	1905873	biological_process	positive regulation of protein localization to cell leading edge
T	1905875	biological_process	negative regulation of postsynaptic density organization
T	1990314	biological_process	cellular response to insulin-like growth factor stimulus
T	2000146	biological_process	negative regulation of cell motility
T	2000147	biological_process	positive regulation of cell motility
T	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
T	2000814	biological_process	positive regulation of barbed-end actin filament capping
U	0000281	biological_process	mitotic cytokinesis
U	0001755	biological_process	neural crest cell migration
U	0001842	biological_process	neural fold formation
U	0003779	molecular_function	actin binding
U	0005102	molecular_function	signaling receptor binding
U	0005515	molecular_function	protein binding
U	0005615	cellular_component	extracellular space
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005856	cellular_component	cytoskeleton
U	0005886	cellular_component	plasma membrane
U	0005911	cellular_component	cell-cell junction
U	0005925	cellular_component	focal adhesion
U	0006606	biological_process	protein import into nucleus
U	0007010	biological_process	cytoskeleton organization
U	0007015	biological_process	actin filament organization
U	0007162	biological_process	negative regulation of cell adhesion
U	0007266	biological_process	Rho protein signal transduction
U	0008154	biological_process	actin polymerization or depolymerization
U	0009615	biological_process	response to virus
U	0010592	biological_process	positive regulation of lamellipodium assembly
U	0010593	biological_process	negative regulation of lamellipodium assembly
U	0014823	biological_process	response to activity
U	0015629	cellular_component	actin cytoskeleton
U	0016020	cellular_component	membrane
U	0016363	cellular_component	nuclear matrix
U	0019903	molecular_function	protein phosphatase binding
U	0021766	biological_process	hippocampus development
U	0022604	biological_process	regulation of cell morphogenesis
U	0030010	biological_process	establishment of cell polarity
U	0030027	cellular_component	lamellipodium
U	0030030	biological_process	cell projection organization
U	0030036	biological_process	actin cytoskeleton organization
U	0030042	biological_process	actin filament depolymerization
U	0030043	biological_process	actin filament fragmentation
U	0030175	cellular_component	filopodium
U	0030307	biological_process	positive regulation of cell growth
U	0030424	cellular_component	axon
U	0030426	cellular_component	growth cone
U	0030835	biological_process	negative regulation of actin filament depolymerization
U	0030836	biological_process	positive regulation of actin filament depolymerization
U	0030864	cellular_component	cortical actin cytoskeleton
U	0031252	cellular_component	cell leading edge
U	0031258	cellular_component	lamellipodium membrane
U	0031915	biological_process	positive regulation of synaptic plasticity
U	0031966	cellular_component	mitochondrial membrane
U	0031982	cellular_component	vesicle
U	0032232	biological_process	negative regulation of actin filament bundle assembly
U	0032587	cellular_component	ruffle membrane
U	0040019	biological_process	positive regulation of embryonic development
U	0042995	cellular_component	cell projection
U	0043025	cellular_component	neuronal cell body
U	0043066	biological_process	negative regulation of apoptotic process
U	0043197	cellular_component	dendritic spine
U	0043200	biological_process	response to amino acid
U	0044794	biological_process	host-mediated activation of viral process
U	0045792	biological_process	negative regulation of cell size
U	0045862	biological_process	positive regulation of proteolysis
U	0048870	biological_process	cell motility
U	0050804	biological_process	modulation of chemical synaptic transmission
U	0051014	biological_process	actin filament severing
U	0051015	molecular_function	actin filament binding
U	0051293	biological_process	establishment of spindle localization
U	0051511	biological_process	negative regulation of unidimensional cell growth
U	0051894	biological_process	positive regulation of focal adhesion assembly
U	0060999	biological_process	positive regulation of dendritic spine development
U	0061001	biological_process	regulation of dendritic spine morphogenesis
U	0070062	cellular_component	extracellular exosome
U	0070301	biological_process	cellular response to hydrogen peroxide
U	0071347	biological_process	cellular response to interleukin-1
U	0071354	biological_process	cellular response to interleukin-6
U	0071356	biological_process	cellular response to tumor necrosis factor
U	0071362	biological_process	cellular response to ether
U	0071364	biological_process	cellular response to epidermal growth factor stimulus
U	0090732	cellular_component	cofilin-actin rod
U	0097060	cellular_component	synaptic membrane
U	0098885	biological_process	modification of postsynaptic actin cytoskeleton
U	0098978	cellular_component	glutamatergic synapse
U	0099092	cellular_component	postsynaptic density, intracellular component
U	1902936	molecular_function	phosphatidylinositol bisphosphate binding
U	1902951	biological_process	negative regulation of dendritic spine maintenance
U	1905873	biological_process	positive regulation of protein localization to cell leading edge
U	1905875	biological_process	negative regulation of postsynaptic density organization
U	1990314	biological_process	cellular response to insulin-like growth factor stimulus
U	2000146	biological_process	negative regulation of cell motility
U	2000147	biological_process	positive regulation of cell motility
U	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
U	2000814	biological_process	positive regulation of barbed-end actin filament capping
V	0000281	biological_process	mitotic cytokinesis
V	0001755	biological_process	neural crest cell migration
V	0001842	biological_process	neural fold formation
V	0003779	molecular_function	actin binding
V	0005102	molecular_function	signaling receptor binding
V	0005515	molecular_function	protein binding
V	0005615	cellular_component	extracellular space
V	0005634	cellular_component	nucleus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005856	cellular_component	cytoskeleton
V	0005886	cellular_component	plasma membrane
V	0005911	cellular_component	cell-cell junction
V	0005925	cellular_component	focal adhesion
V	0006606	biological_process	protein import into nucleus
V	0007010	biological_process	cytoskeleton organization
V	0007015	biological_process	actin filament organization
V	0007162	biological_process	negative regulation of cell adhesion
V	0007266	biological_process	Rho protein signal transduction
V	0008154	biological_process	actin polymerization or depolymerization
V	0009615	biological_process	response to virus
V	0010592	biological_process	positive regulation of lamellipodium assembly
V	0010593	biological_process	negative regulation of lamellipodium assembly
V	0014823	biological_process	response to activity
V	0015629	cellular_component	actin cytoskeleton
V	0016020	cellular_component	membrane
V	0016363	cellular_component	nuclear matrix
V	0019903	molecular_function	protein phosphatase binding
V	0021766	biological_process	hippocampus development
V	0022604	biological_process	regulation of cell morphogenesis
V	0030010	biological_process	establishment of cell polarity
V	0030027	cellular_component	lamellipodium
V	0030030	biological_process	cell projection organization
V	0030036	biological_process	actin cytoskeleton organization
V	0030042	biological_process	actin filament depolymerization
V	0030043	biological_process	actin filament fragmentation
V	0030175	cellular_component	filopodium
V	0030307	biological_process	positive regulation of cell growth
V	0030424	cellular_component	axon
V	0030426	cellular_component	growth cone
V	0030835	biological_process	negative regulation of actin filament depolymerization
V	0030836	biological_process	positive regulation of actin filament depolymerization
V	0030864	cellular_component	cortical actin cytoskeleton
V	0031252	cellular_component	cell leading edge
V	0031258	cellular_component	lamellipodium membrane
V	0031915	biological_process	positive regulation of synaptic plasticity
V	0031966	cellular_component	mitochondrial membrane
V	0031982	cellular_component	vesicle
V	0032232	biological_process	negative regulation of actin filament bundle assembly
V	0032587	cellular_component	ruffle membrane
V	0040019	biological_process	positive regulation of embryonic development
V	0042995	cellular_component	cell projection
V	0043025	cellular_component	neuronal cell body
V	0043066	biological_process	negative regulation of apoptotic process
V	0043197	cellular_component	dendritic spine
V	0043200	biological_process	response to amino acid
V	0044794	biological_process	host-mediated activation of viral process
V	0045792	biological_process	negative regulation of cell size
V	0045862	biological_process	positive regulation of proteolysis
V	0048870	biological_process	cell motility
V	0050804	biological_process	modulation of chemical synaptic transmission
V	0051014	biological_process	actin filament severing
V	0051015	molecular_function	actin filament binding
V	0051293	biological_process	establishment of spindle localization
V	0051511	biological_process	negative regulation of unidimensional cell growth
V	0051894	biological_process	positive regulation of focal adhesion assembly
V	0060999	biological_process	positive regulation of dendritic spine development
V	0061001	biological_process	regulation of dendritic spine morphogenesis
V	0070062	cellular_component	extracellular exosome
V	0070301	biological_process	cellular response to hydrogen peroxide
V	0071347	biological_process	cellular response to interleukin-1
V	0071354	biological_process	cellular response to interleukin-6
V	0071356	biological_process	cellular response to tumor necrosis factor
V	0071362	biological_process	cellular response to ether
V	0071364	biological_process	cellular response to epidermal growth factor stimulus
V	0090732	cellular_component	cofilin-actin rod
V	0097060	cellular_component	synaptic membrane
V	0098885	biological_process	modification of postsynaptic actin cytoskeleton
V	0098978	cellular_component	glutamatergic synapse
V	0099092	cellular_component	postsynaptic density, intracellular component
V	1902936	molecular_function	phosphatidylinositol bisphosphate binding
V	1902951	biological_process	negative regulation of dendritic spine maintenance
V	1905873	biological_process	positive regulation of protein localization to cell leading edge
V	1905875	biological_process	negative regulation of postsynaptic density organization
V	1990314	biological_process	cellular response to insulin-like growth factor stimulus
V	2000146	biological_process	negative regulation of cell motility
V	2000147	biological_process	positive regulation of cell motility
V	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
V	2000814	biological_process	positive regulation of barbed-end actin filament capping
W	0000281	biological_process	mitotic cytokinesis
W	0001755	biological_process	neural crest cell migration
W	0001842	biological_process	neural fold formation
W	0003779	molecular_function	actin binding
W	0005102	molecular_function	signaling receptor binding
W	0005515	molecular_function	protein binding
W	0005615	cellular_component	extracellular space
W	0005634	cellular_component	nucleus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005856	cellular_component	cytoskeleton
W	0005886	cellular_component	plasma membrane
W	0005911	cellular_component	cell-cell junction
W	0005925	cellular_component	focal adhesion
W	0006606	biological_process	protein import into nucleus
W	0007010	biological_process	cytoskeleton organization
W	0007015	biological_process	actin filament organization
W	0007162	biological_process	negative regulation of cell adhesion
W	0007266	biological_process	Rho protein signal transduction
W	0008154	biological_process	actin polymerization or depolymerization
W	0009615	biological_process	response to virus
W	0010592	biological_process	positive regulation of lamellipodium assembly
W	0010593	biological_process	negative regulation of lamellipodium assembly
W	0014823	biological_process	response to activity
W	0015629	cellular_component	actin cytoskeleton
W	0016020	cellular_component	membrane
W	0016363	cellular_component	nuclear matrix
W	0019903	molecular_function	protein phosphatase binding
W	0021766	biological_process	hippocampus development
W	0022604	biological_process	regulation of cell morphogenesis
W	0030010	biological_process	establishment of cell polarity
W	0030027	cellular_component	lamellipodium
W	0030030	biological_process	cell projection organization
W	0030036	biological_process	actin cytoskeleton organization
W	0030042	biological_process	actin filament depolymerization
W	0030043	biological_process	actin filament fragmentation
W	0030175	cellular_component	filopodium
W	0030307	biological_process	positive regulation of cell growth
W	0030424	cellular_component	axon
W	0030426	cellular_component	growth cone
W	0030835	biological_process	negative regulation of actin filament depolymerization
W	0030836	biological_process	positive regulation of actin filament depolymerization
W	0030864	cellular_component	cortical actin cytoskeleton
W	0031252	cellular_component	cell leading edge
W	0031258	cellular_component	lamellipodium membrane
W	0031915	biological_process	positive regulation of synaptic plasticity
W	0031966	cellular_component	mitochondrial membrane
W	0031982	cellular_component	vesicle
W	0032232	biological_process	negative regulation of actin filament bundle assembly
W	0032587	cellular_component	ruffle membrane
W	0040019	biological_process	positive regulation of embryonic development
W	0042995	cellular_component	cell projection
W	0043025	cellular_component	neuronal cell body
W	0043066	biological_process	negative regulation of apoptotic process
W	0043197	cellular_component	dendritic spine
W	0043200	biological_process	response to amino acid
W	0044794	biological_process	host-mediated activation of viral process
W	0045792	biological_process	negative regulation of cell size
W	0045862	biological_process	positive regulation of proteolysis
W	0048870	biological_process	cell motility
W	0050804	biological_process	modulation of chemical synaptic transmission
W	0051014	biological_process	actin filament severing
W	0051015	molecular_function	actin filament binding
W	0051293	biological_process	establishment of spindle localization
W	0051511	biological_process	negative regulation of unidimensional cell growth
W	0051894	biological_process	positive regulation of focal adhesion assembly
W	0060999	biological_process	positive regulation of dendritic spine development
W	0061001	biological_process	regulation of dendritic spine morphogenesis
W	0070062	cellular_component	extracellular exosome
W	0070301	biological_process	cellular response to hydrogen peroxide
W	0071347	biological_process	cellular response to interleukin-1
W	0071354	biological_process	cellular response to interleukin-6
W	0071356	biological_process	cellular response to tumor necrosis factor
W	0071362	biological_process	cellular response to ether
W	0071364	biological_process	cellular response to epidermal growth factor stimulus
W	0090732	cellular_component	cofilin-actin rod
W	0097060	cellular_component	synaptic membrane
W	0098885	biological_process	modification of postsynaptic actin cytoskeleton
W	0098978	cellular_component	glutamatergic synapse
W	0099092	cellular_component	postsynaptic density, intracellular component
W	1902936	molecular_function	phosphatidylinositol bisphosphate binding
W	1902951	biological_process	negative regulation of dendritic spine maintenance
W	1905873	biological_process	positive regulation of protein localization to cell leading edge
W	1905875	biological_process	negative regulation of postsynaptic density organization
W	1990314	biological_process	cellular response to insulin-like growth factor stimulus
W	2000146	biological_process	negative regulation of cell motility
W	2000147	biological_process	positive regulation of cell motility
W	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
W	2000814	biological_process	positive regulation of barbed-end actin filament capping
X	0000281	biological_process	mitotic cytokinesis
X	0001755	biological_process	neural crest cell migration
X	0001842	biological_process	neural fold formation
X	0003779	molecular_function	actin binding
X	0005102	molecular_function	signaling receptor binding
X	0005515	molecular_function	protein binding
X	0005615	cellular_component	extracellular space
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005856	cellular_component	cytoskeleton
X	0005886	cellular_component	plasma membrane
X	0005911	cellular_component	cell-cell junction
X	0005925	cellular_component	focal adhesion
X	0006606	biological_process	protein import into nucleus
X	0007010	biological_process	cytoskeleton organization
X	0007015	biological_process	actin filament organization
X	0007162	biological_process	negative regulation of cell adhesion
X	0007266	biological_process	Rho protein signal transduction
X	0008154	biological_process	actin polymerization or depolymerization
X	0009615	biological_process	response to virus
X	0010592	biological_process	positive regulation of lamellipodium assembly
X	0010593	biological_process	negative regulation of lamellipodium assembly
X	0014823	biological_process	response to activity
X	0015629	cellular_component	actin cytoskeleton
X	0016020	cellular_component	membrane
X	0016363	cellular_component	nuclear matrix
X	0019903	molecular_function	protein phosphatase binding
X	0021766	biological_process	hippocampus development
X	0022604	biological_process	regulation of cell morphogenesis
X	0030010	biological_process	establishment of cell polarity
X	0030027	cellular_component	lamellipodium
X	0030030	biological_process	cell projection organization
X	0030036	biological_process	actin cytoskeleton organization
X	0030042	biological_process	actin filament depolymerization
X	0030043	biological_process	actin filament fragmentation
X	0030175	cellular_component	filopodium
X	0030307	biological_process	positive regulation of cell growth
X	0030424	cellular_component	axon
X	0030426	cellular_component	growth cone
X	0030835	biological_process	negative regulation of actin filament depolymerization
X	0030836	biological_process	positive regulation of actin filament depolymerization
X	0030864	cellular_component	cortical actin cytoskeleton
X	0031252	cellular_component	cell leading edge
X	0031258	cellular_component	lamellipodium membrane
X	0031915	biological_process	positive regulation of synaptic plasticity
X	0031966	cellular_component	mitochondrial membrane
X	0031982	cellular_component	vesicle
X	0032232	biological_process	negative regulation of actin filament bundle assembly
X	0032587	cellular_component	ruffle membrane
X	0040019	biological_process	positive regulation of embryonic development
X	0042995	cellular_component	cell projection
X	0043025	cellular_component	neuronal cell body
X	0043066	biological_process	negative regulation of apoptotic process
X	0043197	cellular_component	dendritic spine
X	0043200	biological_process	response to amino acid
X	0044794	biological_process	host-mediated activation of viral process
X	0045792	biological_process	negative regulation of cell size
X	0045862	biological_process	positive regulation of proteolysis
X	0048870	biological_process	cell motility
X	0050804	biological_process	modulation of chemical synaptic transmission
X	0051014	biological_process	actin filament severing
X	0051015	molecular_function	actin filament binding
X	0051293	biological_process	establishment of spindle localization
X	0051511	biological_process	negative regulation of unidimensional cell growth
X	0051894	biological_process	positive regulation of focal adhesion assembly
X	0060999	biological_process	positive regulation of dendritic spine development
X	0061001	biological_process	regulation of dendritic spine morphogenesis
X	0070062	cellular_component	extracellular exosome
X	0070301	biological_process	cellular response to hydrogen peroxide
X	0071347	biological_process	cellular response to interleukin-1
X	0071354	biological_process	cellular response to interleukin-6
X	0071356	biological_process	cellular response to tumor necrosis factor
X	0071362	biological_process	cellular response to ether
X	0071364	biological_process	cellular response to epidermal growth factor stimulus
X	0090732	cellular_component	cofilin-actin rod
X	0097060	cellular_component	synaptic membrane
X	0098885	biological_process	modification of postsynaptic actin cytoskeleton
X	0098978	cellular_component	glutamatergic synapse
X	0099092	cellular_component	postsynaptic density, intracellular component
X	1902936	molecular_function	phosphatidylinositol bisphosphate binding
X	1902951	biological_process	negative regulation of dendritic spine maintenance
X	1905873	biological_process	positive regulation of protein localization to cell leading edge
X	1905875	biological_process	negative regulation of postsynaptic density organization
X	1990314	biological_process	cellular response to insulin-like growth factor stimulus
X	2000146	biological_process	negative regulation of cell motility
X	2000147	biological_process	positive regulation of cell motility
X	2000784	biological_process	positive regulation of establishment of cell polarity regulating cell shape
X	2000814	biological_process	positive regulation of barbed-end actin filament capping

Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
A	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
A	TRP356-GLU364

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
A	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Modified residue: {"description":"N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2007","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Black E.J.","Gillespie D.A."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"UniProtKB","id":"P60710","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"11955010","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30626964","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1788
Details	Domain: {"description":"ADF-H","evidences":[{"source":"PROSITE-ProRule","id":"PRU00599","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	48
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2005","submissionDatabase":"UniProtKB","authors":["Quadroni M.","Bienvenut W.V."]}},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine; by NRK","evidences":[{"source":"PubMed","id":"12837278","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P18760","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	36
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	12
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	12
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"30550596","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	24
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---