3IZQ
Structure of the Dom34-Hbs1-GDPNP complex bound to a translating ribosome
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| 0 | 0004521 | molecular_function | RNA endonuclease activity |
| 0 | 0005515 | molecular_function | protein binding |
| 0 | 0005737 | cellular_component | cytoplasm |
| 0 | 0006412 | biological_process | translation |
| 0 | 0006417 | biological_process | regulation of translation |
| 0 | 0016070 | biological_process | RNA metabolic process |
| 0 | 0032790 | biological_process | ribosome disassembly |
| 0 | 0043022 | molecular_function | ribosome binding |
| 0 | 0045727 | biological_process | positive regulation of translation |
| 0 | 0045948 | biological_process | positive regulation of translational initiation |
| 0 | 0046872 | molecular_function | metal ion binding |
| 0 | 0051301 | biological_process | cell division |
| 0 | 0051321 | biological_process | meiotic cell cycle |
| 0 | 0070481 | biological_process | nuclear-transcribed mRNA catabolic process, non-stop decay |
| 0 | 0070651 | biological_process | nonfunctional rRNA decay |
| 0 | 0070966 | biological_process | nuclear-transcribed mRNA catabolic process, no-go decay |
| 0 | 0071025 | biological_process | RNA surveillance |
| 0 | 0072344 | biological_process | rescue of stalled ribosome |
| 0 | 1990533 | cellular_component | Dom34-Hbs1 complex |
| 1 | 0000166 | molecular_function | nucleotide binding |
| 1 | 0003746 | molecular_function | translation elongation factor activity |
| 1 | 0003924 | molecular_function | GTPase activity |
| 1 | 0005515 | molecular_function | protein binding |
| 1 | 0005525 | molecular_function | GTP binding |
| 1 | 0005737 | cellular_component | cytoplasm |
| 1 | 0005829 | cellular_component | cytosol |
| 1 | 0006412 | biological_process | translation |
| 1 | 0006414 | biological_process | translational elongation |
| 1 | 0006417 | biological_process | regulation of translation |
| 1 | 0016787 | molecular_function | hydrolase activity |
| 1 | 0032790 | biological_process | ribosome disassembly |
| 1 | 0043022 | molecular_function | ribosome binding |
| 1 | 0045727 | biological_process | positive regulation of translation |
| 1 | 0045948 | biological_process | positive regulation of translational initiation |
| 1 | 0070651 | biological_process | nonfunctional rRNA decay |
| 1 | 0070966 | biological_process | nuclear-transcribed mRNA catabolic process, no-go decay |
| 1 | 0072344 | biological_process | rescue of stalled ribosome |
| 1 | 1990533 | cellular_component | Dom34-Hbs1 complex |
Functional Information from PROSITE/UniProt
| site_id | PS00301 |
| Number of Residues | 16 |
| Details | G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DQtneEReRGVTVsiC |
| Chain | Residue | Details |
| 1 | ASP221-CYS236 |
| site_id | PS00933 |
| Number of Residues | 13 |
| Details | FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. GkSsfKFAWIMDQ |
| Chain | Residue | Details |
| 1 | GLY210-GLN222 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 225 |
| Details | Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21102444","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3P27","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
