3IZQ

Structure of the Dom34-Hbs1-GDPNP complex bound to a translating ribosome

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0004521	molecular_function	RNA endonuclease activity
0	0005515	molecular_function	protein binding
0	0005737	cellular_component	cytoplasm
0	0006412	biological_process	translation
0	0006417	biological_process	regulation of translation
0	0010467	biological_process	gene expression
0	0016070	biological_process	RNA metabolic process
0	0032790	biological_process	ribosome disassembly
0	0043022	molecular_function	ribosome binding
0	0045727	biological_process	positive regulation of translation
0	0045948	biological_process	positive regulation of translational initiation
0	0046872	molecular_function	metal ion binding
0	0051301	biological_process	cell division
0	0051321	biological_process	meiotic cell cycle
0	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
0	0070651	biological_process	nonfunctional rRNA decay
0	0070966	biological_process	nuclear-transcribed mRNA catabolic process, no-go decay
0	0071025	biological_process	RNA surveillance
0	0072344	biological_process	rescue of stalled ribosome
0	1990533	cellular_component	Dom34-Hbs1 complex
1	0003746	molecular_function	translation elongation factor activity
1	0003924	molecular_function	GTPase activity
1	0005515	molecular_function	protein binding
1	0005525	molecular_function	GTP binding
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0006412	biological_process	translation
1	0006414	biological_process	translational elongation
1	0006417	biological_process	regulation of translation
1	0016787	molecular_function	hydrolase activity
1	0032790	biological_process	ribosome disassembly
1	0043022	molecular_function	ribosome binding
1	0045727	biological_process	positive regulation of translation
1	0045948	biological_process	positive regulation of translational initiation
1	0070651	biological_process	nonfunctional rRNA decay
1	0070966	biological_process	nuclear-transcribed mRNA catabolic process, no-go decay
1	0072344	biological_process	rescue of stalled ribosome
1	1990533	cellular_component	Dom34-Hbs1 complex

Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DQtneEReRGVTVsiC

Chain	Residue	Details
1	ASP221-CYS236

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site_id	PS00933
Number of Residues	13
Details	FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. GkSsfKFAWIMDQ

Chain	Residue	Details
1	GLY210-GLN222

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:21102444, ECO:0007744|PDB:3P27

Chain	Residue	Details
1	GLY174
1	ASN313
1	SER352

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
1	SER124

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