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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

3IYV

Clathrin D6 coat as full-length Triskelions

Functional Information from GO Data
ChainGOidnamespacecontents
A0000278biological_processmitotic cell cycle
A0005198molecular_functionstructural molecule activity
A0005515molecular_functionprotein binding
A0005739cellular_componentmitochondrion
A0005819cellular_componentspindle
A0005905cellular_componentclathrin-coated pit
A0006886biological_processintracellular protein transport
A0006898biological_processreceptor-mediated endocytosis
A0006914biological_processautophagy
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0019904molecular_functionprotein domain specific binding
A0030117cellular_componentmembrane coat
A0030130cellular_componentclathrin coat of trans-Golgi network vesicle
A0030132cellular_componentclathrin coat of coated pit
A0030659cellular_componentcytoplasmic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0032051molecular_functionclathrin light chain binding
A0042470cellular_componentmelanosome
A0042802molecular_functionidentical protein binding
A0045334cellular_componentclathrin-coated endocytic vesicle
A0048268biological_processclathrin coat assembly
A0051301biological_processcell division
A0071439cellular_componentclathrin complex
A0072318biological_processclathrin coat disassembly
A0097718molecular_functiondisordered domain specific binding
A1900126biological_processnegative regulation of hyaluronan biosynthetic process
A1990763molecular_functionarrestin family protein binding
B0000278biological_processmitotic cell cycle
B0005198molecular_functionstructural molecule activity
B0005515molecular_functionprotein binding
B0005739cellular_componentmitochondrion
B0005819cellular_componentspindle
B0005905cellular_componentclathrin-coated pit
B0006886biological_processintracellular protein transport
B0006898biological_processreceptor-mediated endocytosis
B0006914biological_processautophagy
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0019904molecular_functionprotein domain specific binding
B0030117cellular_componentmembrane coat
B0030130cellular_componentclathrin coat of trans-Golgi network vesicle
B0030132cellular_componentclathrin coat of coated pit
B0030659cellular_componentcytoplasmic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0032051molecular_functionclathrin light chain binding
B0042470cellular_componentmelanosome
B0042802molecular_functionidentical protein binding
B0045334cellular_componentclathrin-coated endocytic vesicle
B0048268biological_processclathrin coat assembly
B0051301biological_processcell division
B0071439cellular_componentclathrin complex
B0072318biological_processclathrin coat disassembly
B0097718molecular_functiondisordered domain specific binding
B1900126biological_processnegative regulation of hyaluronan biosynthetic process
B1990763molecular_functionarrestin family protein binding
C0000278biological_processmitotic cell cycle
C0005198molecular_functionstructural molecule activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005819cellular_componentspindle
C0005905cellular_componentclathrin-coated pit
C0006886biological_processintracellular protein transport
C0006898biological_processreceptor-mediated endocytosis
C0006914biological_processautophagy
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0019904molecular_functionprotein domain specific binding
C0030117cellular_componentmembrane coat
C0030130cellular_componentclathrin coat of trans-Golgi network vesicle
C0030132cellular_componentclathrin coat of coated pit
C0030659cellular_componentcytoplasmic vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
C0032051molecular_functionclathrin light chain binding
C0042470cellular_componentmelanosome
C0042802molecular_functionidentical protein binding
C0045334cellular_componentclathrin-coated endocytic vesicle
C0048268biological_processclathrin coat assembly
C0051301biological_processcell division
C0071439cellular_componentclathrin complex
C0072318biological_processclathrin coat disassembly
C0097718molecular_functiondisordered domain specific binding
C1900126biological_processnegative regulation of hyaluronan biosynthetic process
C1990763molecular_functionarrestin family protein binding
D0000278biological_processmitotic cell cycle
D0005198molecular_functionstructural molecule activity
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005819cellular_componentspindle
D0005905cellular_componentclathrin-coated pit
D0006886biological_processintracellular protein transport
D0006898biological_processreceptor-mediated endocytosis
D0006914biological_processautophagy
D0016020cellular_componentmembrane
D0016192biological_processvesicle-mediated transport
D0019904molecular_functionprotein domain specific binding
D0030117cellular_componentmembrane coat
D0030130cellular_componentclathrin coat of trans-Golgi network vesicle
D0030132cellular_componentclathrin coat of coated pit
D0030659cellular_componentcytoplasmic vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
D0032051molecular_functionclathrin light chain binding
D0042470cellular_componentmelanosome
D0042802molecular_functionidentical protein binding
D0045334cellular_componentclathrin-coated endocytic vesicle
D0048268biological_processclathrin coat assembly
D0051301biological_processcell division
D0071439cellular_componentclathrin complex
D0072318biological_processclathrin coat disassembly
D0097718molecular_functiondisordered domain specific binding
D1900126biological_processnegative regulation of hyaluronan biosynthetic process
D1990763molecular_functionarrestin family protein binding
E0000278biological_processmitotic cell cycle
E0005198molecular_functionstructural molecule activity
E0005515molecular_functionprotein binding
E0005739cellular_componentmitochondrion
E0005819cellular_componentspindle
E0005905cellular_componentclathrin-coated pit
E0006886biological_processintracellular protein transport
E0006898biological_processreceptor-mediated endocytosis
E0006914biological_processautophagy
E0016020cellular_componentmembrane
E0016192biological_processvesicle-mediated transport
E0019904molecular_functionprotein domain specific binding
E0030117cellular_componentmembrane coat
E0030130cellular_componentclathrin coat of trans-Golgi network vesicle
E0030132cellular_componentclathrin coat of coated pit
E0030659cellular_componentcytoplasmic vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0032051molecular_functionclathrin light chain binding
E0042470cellular_componentmelanosome
E0042802molecular_functionidentical protein binding
E0045334cellular_componentclathrin-coated endocytic vesicle
E0048268biological_processclathrin coat assembly
E0051301biological_processcell division
E0071439cellular_componentclathrin complex
E0072318biological_processclathrin coat disassembly
E0097718molecular_functiondisordered domain specific binding
E1900126biological_processnegative regulation of hyaluronan biosynthetic process
E1990763molecular_functionarrestin family protein binding
F0000278biological_processmitotic cell cycle
F0005198molecular_functionstructural molecule activity
F0005515molecular_functionprotein binding
F0005739cellular_componentmitochondrion
F0005819cellular_componentspindle
F0005905cellular_componentclathrin-coated pit
F0006886biological_processintracellular protein transport
F0006898biological_processreceptor-mediated endocytosis
F0006914biological_processautophagy
F0016020cellular_componentmembrane
F0016192biological_processvesicle-mediated transport
F0019904molecular_functionprotein domain specific binding
F0030117cellular_componentmembrane coat
F0030130cellular_componentclathrin coat of trans-Golgi network vesicle
F0030132cellular_componentclathrin coat of coated pit
F0030659cellular_componentcytoplasmic vesicle membrane
F0031410cellular_componentcytoplasmic vesicle
F0032051molecular_functionclathrin light chain binding
F0042470cellular_componentmelanosome
F0042802molecular_functionidentical protein binding
F0045334cellular_componentclathrin-coated endocytic vesicle
F0048268biological_processclathrin coat assembly
F0051301biological_processcell division
F0071439cellular_componentclathrin complex
F0072318biological_processclathrin coat disassembly
F0097718molecular_functiondisordered domain specific binding
F1900126biological_processnegative regulation of hyaluronan biosynthetic process
F1990763molecular_functionarrestin family protein binding
G0000278biological_processmitotic cell cycle
G0005198molecular_functionstructural molecule activity
G0005515molecular_functionprotein binding
G0005739cellular_componentmitochondrion
G0005819cellular_componentspindle
G0005905cellular_componentclathrin-coated pit
G0006886biological_processintracellular protein transport
G0006898biological_processreceptor-mediated endocytosis
G0006914biological_processautophagy
G0016020cellular_componentmembrane
G0016192biological_processvesicle-mediated transport
G0019904molecular_functionprotein domain specific binding
G0030117cellular_componentmembrane coat
G0030130cellular_componentclathrin coat of trans-Golgi network vesicle
G0030132cellular_componentclathrin coat of coated pit
G0030659cellular_componentcytoplasmic vesicle membrane
G0031410cellular_componentcytoplasmic vesicle
G0032051molecular_functionclathrin light chain binding
G0042470cellular_componentmelanosome
G0042802molecular_functionidentical protein binding
G0045334cellular_componentclathrin-coated endocytic vesicle
G0048268biological_processclathrin coat assembly
G0051301biological_processcell division
G0071439cellular_componentclathrin complex
G0072318biological_processclathrin coat disassembly
G0097718molecular_functiondisordered domain specific binding
G1900126biological_processnegative regulation of hyaluronan biosynthetic process
G1990763molecular_functionarrestin family protein binding
H0000278biological_processmitotic cell cycle
H0005198molecular_functionstructural molecule activity
H0005515molecular_functionprotein binding
H0005739cellular_componentmitochondrion
H0005819cellular_componentspindle
H0005905cellular_componentclathrin-coated pit
H0006886biological_processintracellular protein transport
H0006898biological_processreceptor-mediated endocytosis
H0006914biological_processautophagy
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0019904molecular_functionprotein domain specific binding
H0030117cellular_componentmembrane coat
H0030130cellular_componentclathrin coat of trans-Golgi network vesicle
H0030132cellular_componentclathrin coat of coated pit
H0030659cellular_componentcytoplasmic vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
H0032051molecular_functionclathrin light chain binding
H0042470cellular_componentmelanosome
H0042802molecular_functionidentical protein binding
H0045334cellular_componentclathrin-coated endocytic vesicle
H0048268biological_processclathrin coat assembly
H0051301biological_processcell division
H0071439cellular_componentclathrin complex
H0072318biological_processclathrin coat disassembly
H0097718molecular_functiondisordered domain specific binding
H1900126biological_processnegative regulation of hyaluronan biosynthetic process
H1990763molecular_functionarrestin family protein binding
I0000278biological_processmitotic cell cycle
I0005198molecular_functionstructural molecule activity
I0005515molecular_functionprotein binding
I0005739cellular_componentmitochondrion
I0005819cellular_componentspindle
I0005905cellular_componentclathrin-coated pit
I0006886biological_processintracellular protein transport
I0006898biological_processreceptor-mediated endocytosis
I0006914biological_processautophagy
I0016020cellular_componentmembrane
I0016192biological_processvesicle-mediated transport
I0019904molecular_functionprotein domain specific binding
I0030117cellular_componentmembrane coat
I0030130cellular_componentclathrin coat of trans-Golgi network vesicle
I0030132cellular_componentclathrin coat of coated pit
I0030659cellular_componentcytoplasmic vesicle membrane
I0031410cellular_componentcytoplasmic vesicle
I0032051molecular_functionclathrin light chain binding
I0042470cellular_componentmelanosome
I0042802molecular_functionidentical protein binding
I0045334cellular_componentclathrin-coated endocytic vesicle
I0048268biological_processclathrin coat assembly
I0051301biological_processcell division
I0071439cellular_componentclathrin complex
I0072318biological_processclathrin coat disassembly
I0097718molecular_functiondisordered domain specific binding
I1900126biological_processnegative regulation of hyaluronan biosynthetic process
I1990763molecular_functionarrestin family protein binding
J0005198molecular_functionstructural molecule activity
J0006886biological_processintracellular protein transport
J0016192biological_processvesicle-mediated transport
J0030130cellular_componentclathrin coat of trans-Golgi network vesicle
J0030132cellular_componentclathrin coat of coated pit
K0005198molecular_functionstructural molecule activity
K0006886biological_processintracellular protein transport
K0016192biological_processvesicle-mediated transport
K0030130cellular_componentclathrin coat of trans-Golgi network vesicle
K0030132cellular_componentclathrin coat of coated pit
L0005198molecular_functionstructural molecule activity
L0006886biological_processintracellular protein transport
L0016192biological_processvesicle-mediated transport
L0030130cellular_componentclathrin coat of trans-Golgi network vesicle
L0030132cellular_componentclathrin coat of coated pit
M0005198molecular_functionstructural molecule activity
M0006886biological_processintracellular protein transport
M0016192biological_processvesicle-mediated transport
M0030130cellular_componentclathrin coat of trans-Golgi network vesicle
M0030132cellular_componentclathrin coat of coated pit
N0005198molecular_functionstructural molecule activity
N0006886biological_processintracellular protein transport
N0016192biological_processvesicle-mediated transport
N0030130cellular_componentclathrin coat of trans-Golgi network vesicle
N0030132cellular_componentclathrin coat of coated pit
O0005198molecular_functionstructural molecule activity
O0006886biological_processintracellular protein transport
O0016192biological_processvesicle-mediated transport
O0030130cellular_componentclathrin coat of trans-Golgi network vesicle
O0030132cellular_componentclathrin coat of coated pit
P0005198molecular_functionstructural molecule activity
P0006886biological_processintracellular protein transport
P0016192biological_processvesicle-mediated transport
P0030130cellular_componentclathrin coat of trans-Golgi network vesicle
P0030132cellular_componentclathrin coat of coated pit
Q0005198molecular_functionstructural molecule activity
Q0006886biological_processintracellular protein transport
Q0016192biological_processvesicle-mediated transport
Q0030130cellular_componentclathrin coat of trans-Golgi network vesicle
Q0030132cellular_componentclathrin coat of coated pit
R0005198molecular_functionstructural molecule activity
R0006886biological_processintracellular protein transport
R0016192biological_processvesicle-mediated transport
R0030130cellular_componentclathrin coat of trans-Golgi network vesicle
R0030132cellular_componentclathrin coat of coated pit
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1314
DetailsRepeat: {"description":"CHCR 1"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues1278
DetailsRepeat: {"description":"CHCR 2"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1251
DetailsRepeat: {"description":"CHCR 3"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1305
DetailsRepeat: {"description":"CHCR 4"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues1269
DetailsRepeat: {"description":"CHCR 5"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues1314
DetailsRepeat: {"description":"CHCR 6"}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues1287
DetailsRepeat: {"description":"CHCR 7"}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues4293
DetailsRegion: {"description":"Globular terminal domain"}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues387
DetailsRegion: {"description":"WD40-like repeat 1"}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues351
DetailsRegion: {"description":"WD40-like repeat 2"}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues369
DetailsRegion: {"description":"WD40-like repeat 3"}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues405
DetailsRegion: {"description":"WD40-like repeat 4"}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues549
DetailsRegion: {"description":"WD40-like repeat 5"}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues387
DetailsRegion: {"description":"WD40-like repeat 6"}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues252
DetailsRegion: {"description":"WD40-like repeat 7"}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues144
DetailsRegion: {"description":"Binding site for the uncoating ATPase, involved in lattice disassembly","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues387
DetailsRegion: {"description":"Flexible linker"}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues990
DetailsRegion: {"description":"Distal segment"}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues2781
DetailsRegion: {"description":"Involved in binding clathrin light chain"}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues9
DetailsModified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"Q00610","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI21
Number of Residues27
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q00610","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI22
Number of Residues9
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI23
Number of Residues36
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI24
Number of Residues9
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q00610","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI25
Number of Residues18
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q00610","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI26
Number of Residues9
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI27
Number of Residues18
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q00610","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI28
Number of Residues9
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI29
Number of Residues9
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI30
Number of Residues558
DetailsRegion: {"description":"Involved in binding clathrin heavy chain"}
ChainResidueDetails
site_idSWS_FT_FI31
Number of Residues9
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P09496","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

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PDB entries from 2025-11-05

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