3IWD

T. maritima AdoMetDC complex with 5'-Deoxy-5'-dimethyl thioadenosine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004014	molecular_function	adenosylmethionine decarboxylase activity
A	0008295	biological_process	spermidine biosynthetic process
B	0004014	molecular_function	adenosylmethionine decarboxylase activity
B	0008295	biological_process	spermidine biosynthetic process
C	0004014	molecular_function	adenosylmethionine decarboxylase activity
C	0008295	biological_process	spermidine biosynthetic process
D	0004014	molecular_function	adenosylmethionine decarboxylase activity
D	0008295	biological_process	spermidine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE M2T A 368

Chain	Residue
A	THR69
B	SER55
D	SER61
D	GLU62
A	TRP70
A	PRO71
A	GLU72
B	TYR35
B	PHE49
B	LEU50
B	TYR52
B	GLY53

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE M2T D 368

Chain	Residue
B	GLU62
C	THR69
C	TRP70
C	PRO71
C	GLU72
D	PHE49
D	LEU50
D	TYR52
D	GLY53
D	VAL54
D	SER55

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor; for processing activity => ECO:0000305|PubMed:15150268

Chain	Residue	Details
A	HIS68
C	HIS68

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor; for catalytic activity => ECO:0000305|PubMed:15150268

Chain	Residue	Details
A	CYS83
C	CYS83

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 225

Chain	Residue	Details
A	HIS68	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	CYS83	hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor

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site_id	MCSA2
Number of Residues	2
Details	M-CSA 225

Chain	Residue	Details
C	HIS68	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	CYS83	hydrogen bond acceptor, hydrogen bond donor, polar interaction, proton acceptor, proton donor

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