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3IU3

Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
B0002250biological_processadaptive immune response
B0003823molecular_functionantigen binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005886cellular_componentplasma membrane
B0006955biological_processimmune response
B0016064biological_processimmunoglobulin mediated immune response
B0019814cellular_componentimmunoglobulin complex
B0050853biological_processB cell receptor signaling pathway
B0070062cellular_componentextracellular exosome
B0071735cellular_componentIgG immunoglobulin complex
B0071738cellular_componentIgD immunoglobulin complex
B0071742cellular_componentIgE immunoglobulin complex
B0071745cellular_componentIgA immunoglobulin complex
B0071753cellular_componentIgM immunoglobulin complex
B0072562cellular_componentblood microparticle
D0002250biological_processadaptive immune response
D0003823molecular_functionantigen binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005886cellular_componentplasma membrane
D0006955biological_processimmune response
D0016064biological_processimmunoglobulin mediated immune response
D0019814cellular_componentimmunoglobulin complex
D0050853biological_processB cell receptor signaling pathway
D0070062cellular_componentextracellular exosome
D0071735cellular_componentIgG immunoglobulin complex
D0071738cellular_componentIgD immunoglobulin complex
D0071742cellular_componentIgE immunoglobulin complex
D0071745cellular_componentIgA immunoglobulin complex
D0071753cellular_componentIgM immunoglobulin complex
D0072562cellular_componentblood microparticle
I0004911molecular_functioninterleukin-2 receptor activity
I0019976molecular_functioninterleukin-2 binding
J0004911molecular_functioninterleukin-2 receptor activity
J0019976molecular_functioninterleukin-2 binding
K0004911molecular_functioninterleukin-2 receptor activity
K0019976molecular_functioninterleukin-2 binding
L0002250biological_processadaptive immune response
L0003823molecular_functionantigen binding
L0005576cellular_componentextracellular region
L0005615cellular_componentextracellular space
L0005886cellular_componentplasma membrane
L0006955biological_processimmune response
L0016064biological_processimmunoglobulin mediated immune response
L0019814cellular_componentimmunoglobulin complex
L0050853biological_processB cell receptor signaling pathway
L0070062cellular_componentextracellular exosome
L0071735cellular_componentIgG immunoglobulin complex
L0071738cellular_componentIgD immunoglobulin complex
L0071742cellular_componentIgE immunoglobulin complex
L0071745cellular_componentIgA immunoglobulin complex
L0071753cellular_componentIgM immunoglobulin complex
L0072562cellular_componentblood microparticle
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00290
残基数7
詳細IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
鎖名残基詳細
ATYR196-HIS202
BTYR189-HIS195

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数6
詳細CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3134887
鎖名残基詳細
IASN49
IASN68
JASN49
JASN68
KASN49
KASN68

site_idSWS_FT_FI2
残基数12
詳細CARBOHYD: O-linked (GalNAc...) threonine => ECO:0000269|PubMed:3134887
鎖名残基詳細
ITHR197
KTHR203
KTHR208
KTHR216
ITHR203
ITHR208
ITHR216
JTHR197
JTHR203
JTHR208
JTHR216
KTHR197

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件を2024-09-18に公開中

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