3IT6
The Crystal Structure of Ornithine Acetyltransferase complexed with Ornithine from Mycobacterium tuberculosis (Rv1653) at 2.4 A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| D | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| D | 0006526 | biological_process | L-arginine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ORN B 1 |
| Chain | Residue |
| A | THR166 |
| B | SER404 |
| A | LYS189 |
| A | GLY192 |
| A | MET193 |
| A | HOH381 |
| B | HOH102 |
| B | THR200 |
| B | GLU280 |
| B | ASN399 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ORN D 1 |
| Chain | Residue |
| B | ARG325 |
| C | THR127 |
| C | THR166 |
| C | LYS189 |
| C | GLY192 |
| C | MET193 |
| D | HOH77 |
| D | HOH80 |
| D | THR200 |
| D | GLU280 |
| D | ASN399 |
| D | SER404 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
