3IT5

Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis
B	0004222	molecular_function	metalloendopeptidase activity
B	0006508	biological_process	proteolysis
E	0004222	molecular_function	metalloendopeptidase activity
E	0006508	biological_process	proteolysis
G	0004222	molecular_function	metalloendopeptidase activity
G	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 183

Chain	Residue
A	HIS23
A	ASP36
A	HIS122
A	HOH222
A	HOH369

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 183

Chain	Residue
B	HIS23
B	ASP36
B	HIS122
B	HOH370

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN E 183

Chain	Residue
E	HIS23
E	ASP36
E	HIS122
E	HOH393
E	HOH395

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN G 183

Chain	Residue
G	HIS23
G	ASP36
G	HIS122
G	HOH368
G	HOH454

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"20026068","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20026068","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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