3IT4
The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| D | 0004358 | molecular_function | L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor |
| D | 0006526 | biological_process | L-arginine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 500 |
| Chain | Residue |
| A | ALA52 |
| A | GLY53 |
| A | LEU72 |
| A | THR73 |
| A | HOH233 |
| A | HOH237 |
| A | HOH354 |
| B | GLU217 |
| B | ARG221 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 501 |
| Chain | Residue |
| B | HOH174 |
| B | HOH191 |
| B | ASP234 |
| B | GLY235 |
| B | ARG308 |
| B | HOH439 |
| D | ARG308 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 601 |
| Chain | Residue |
| B | HOH193 |
| B | ASN322 |
| B | ARG325 |
| B | HOH425 |
| B | HOH564 |
| C | LEU129 |
| C | MET193 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 502 |
| Chain | Residue |
| C | ASP158 |
| C | HIS162 |
| C | HOH246 |
| C | HOH393 |
| C | HOH466 |
| D | HOH130 |
| D | GLN257 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BEZ C 503 |
| Chain | Residue |
| C | ARG9 |
| C | GLN14 |
| C | HIS177 |
| D | ARG221 |
| D | ARG222 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT D 601 |
| Chain | Residue |
| D | ASN322 |
| D | ARG325 |
| D | HOH432 |
| D | HOH590 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
