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3ILI

Crystal structure of E. coli HPPK(D95A)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003848molecular_function2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
A0005524molecular_functionATP binding
A0009396biological_processfolic acid-containing compound biosynthetic process
A0016301molecular_functionkinase activity
A0046654biological_processtetrahydrofolate biosynthetic process
A0046656biological_processfolic acid biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CL A 191
ChainResidue
APRO114
ALYS119
APHE137
APRO138
AASP139
AHOH350

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE TRS A 192
ChainResidue
AGLU16
AHOH351

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE ACT A 193
ChainResidue
ALEU11
AGLN17
AGLN80
AGLY81
ATHR93
ALEU94
AHOH418
ASER9

Catalytic Information from CSA
site_idMCSA1
Number of Residues4
DetailsM-CSA 151
ChainResidueDetails
AARG82electrostatic stabiliser, hydrogen bond donor
AARG92electrostatic stabiliser, hydrogen bond donor
AALA95metal ligand
AASP97metal ligand

219140

PDB entries from 2024-05-01

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