3IKH
Crystal structure of Ribokinase in Complex with ATP and glycerol in the active site from Klebsiella pneumoniae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004747 | molecular_function | ribokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006014 | biological_process | D-ribose metabolic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0019303 | biological_process | D-ribose catabolic process |
| A | 0044281 | biological_process | small molecule metabolic process |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004747 | molecular_function | ribokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006014 | biological_process | D-ribose metabolic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0019303 | biological_process | D-ribose catabolic process |
| B | 0044281 | biological_process | small molecule metabolic process |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004747 | molecular_function | ribokinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006014 | biological_process | D-ribose metabolic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0019303 | biological_process | D-ribose catabolic process |
| C | 0044281 | biological_process | small molecule metabolic process |
| C | 0046835 | biological_process | carbohydrate phosphorylation |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004747 | molecular_function | ribokinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006014 | biological_process | D-ribose metabolic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0019303 | biological_process | D-ribose catabolic process |
| D | 0044281 | biological_process | small molecule metabolic process |
| D | 0046835 | biological_process | carbohydrate phosphorylation |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ATP A 900 |
| Chain | Residue |
| A | ASN182 |
| A | HOH328 |
| A | HOH331 |
| A | HOH346 |
| A | HOH360 |
| A | HOH390 |
| A | THR200 |
| A | GLY202 |
| A | GLY205 |
| A | VAL220 |
| A | GLY231 |
| A | PHE234 |
| A | ALA261 |
| A | HOH306 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP B 900 |
| Chain | Residue |
| B | LYS39 |
| B | ASN182 |
| B | THR200 |
| B | GLN201 |
| B | GLY202 |
| B | ALA203 |
| B | GLY205 |
| B | VAL220 |
| B | ALA230 |
| B | GLY231 |
| B | PHE234 |
| B | ALA261 |
| B | HOH302 |
| B | HOH308 |
| B | HOH311 |
| B | HOH317 |
| B | HOH319 |
| B | HOH324 |
| B | HOH344 |
| B | HOH358 |
| B | HOH370 |
| B | HOH375 |
| B | HOH395 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP C 900 |
| Chain | Residue |
| C | ASN182 |
| C | THR200 |
| C | GLN201 |
| C | GLY202 |
| C | ALA203 |
| C | GLY205 |
| C | VAL220 |
| C | GLY229 |
| C | ALA230 |
| C | GLY231 |
| C | PHE234 |
| C | ALA261 |
| C | HOH300 |
| C | HOH303 |
| C | HOH304 |
| C | HOH330 |
| C | HOH336 |
| C | HOH360 |
| C | HOH377 |
| C | HOH387 |
| C | HOH388 |
| C | HOH391 |
| C | HOH393 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 501 |
| Chain | Residue |
| C | THR10 |
| C | ASP12 |
| C | GLY38 |
| C | ASN42 |
| C | SER93 |
| C | ASP232 |
| C | HOH330 |
| C | HOH367 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ATP D 900 |
| Chain | Residue |
| D | LYS39 |
| D | ASN182 |
| D | THR200 |
| D | GLN201 |
| D | GLY202 |
| D | ALA203 |
| D | GLY205 |
| D | VAL220 |
| D | ALA230 |
| D | GLY231 |
| D | PHE234 |
| D | ALA261 |
| D | HOH300 |
| D | HOH316 |
| D | HOH328 |
| D | HOH334 |
| D | HOH353 |
| D | HOH356 |
| D | HOH358 |
| D | HOH361 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D 501 |
| Chain | Residue |
| D | THR10 |
| D | ASP12 |
| D | GLY38 |
| D | ASN42 |
| D | SER93 |
| D | ASP232 |
| D | HOH356 |
Functional Information from PROSITE/UniProt
| site_id | PS00583 |
| Number of Residues | 25 |
| Details | PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGkGaNQAiiLsRCGietrliaatG |
| Chain | Residue | Details |
| A | GLY37-GLY61 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| A | GLY231 | |
| A | GLY229 | |
| A | ASP232 | |
| A | ALA230 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| B | GLY231 | |
| B | GLY229 | |
| B | ASP232 | |
| B | ALA230 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| C | GLY231 | |
| C | GLY229 | |
| C | ASP232 | |
| C | ALA230 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| D | GLY231 | |
| D | GLY229 | |
| D | ASP232 | |
| D | ALA230 |
