3IJD
Uncharacterized protein Cthe_2304 from Clostridium thermocellum binds two copies of 5-methyl-5,6,7,8-tetrahydrofolic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004489 | molecular_function | methylenetetrahydrofolate reductase [NAD(P)H] activity |
| A | 0006555 | biological_process | methionine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0004489 | molecular_function | methylenetetrahydrofolate reductase [NAD(P)H] activity |
| B | 0006555 | biological_process | methionine metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE C2F A 314 |
| Chain | Residue |
| A | THR19 |
| A | LYS172 |
| A | GLN183 |
| A | LEU231 |
| A | GLU280 |
| A | HOH329 |
| A | HOH349 |
| A | HOH408 |
| A | TYR52 |
| A | ASP53 |
| A | LEU54 |
| A | VAL121 |
| A | GLY122 |
| A | ALA123 |
| A | ILE155 |
| A | ARG158 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE C2F A 315 |
| Chain | Residue |
| A | THR19 |
| A | PRO20 |
| A | LYS22 |
| A | LYS29 |
| A | ILE33 |
| A | ARG40 |
| A | THR72 |
| A | PHE227 |
| A | VAL282 |
| A | VAL284 |
| A | LYS286 |
| A | ILE289 |
| A | HOH340 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE C2F B 314 |
| Chain | Residue |
| B | THR19 |
| B | TYR52 |
| B | ASP53 |
| B | LEU54 |
| B | VAL121 |
| B | GLY122 |
| B | ALA123 |
| B | ILE155 |
| B | ARG158 |
| B | LYS172 |
| B | GLN183 |
| B | LEU231 |
| B | GLU280 |
| B | HOH322 |
| B | HOH325 |
| B | HOH327 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE C2F B 315 |
| Chain | Residue |
| B | THR19 |
| B | PRO20 |
| B | LYS22 |
| B | LYS29 |
| B | ILE33 |
| B | LYS36 |
| B | ARG40 |
| B | ILE70 |
| B | THR72 |
| B | LYS223 |
| B | PHE227 |
| B | VAL282 |
| B | VAL284 |
| B | LYS286 |
| B | HOH349 |
| B | HOH358 |
