3IJD

Uncharacterized protein Cthe_2304 from Clostridium thermocellum binds two copies of 5-methyl-5,6,7,8-tetrahydrofolic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004489	molecular_function	methylenetetrahydrofolate reductase [NAD(P)H] activity
A	0006555	biological_process	L-methionine metabolic process
A	0035999	biological_process	tetrahydrofolate interconversion
B	0004489	molecular_function	methylenetetrahydrofolate reductase [NAD(P)H] activity
B	0006555	biological_process	L-methionine metabolic process
B	0035999	biological_process	tetrahydrofolate interconversion

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE C2F A 314

Chain	Residue
A	THR19
A	LYS172
A	GLN183
A	LEU231
A	GLU280
A	HOH329
A	HOH349
A	HOH408
A	TYR52
A	ASP53
A	LEU54
A	VAL121
A	GLY122
A	ALA123
A	ILE155
A	ARG158

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE C2F A 315

Chain	Residue
A	THR19
A	PRO20
A	LYS22
A	LYS29
A	ILE33
A	ARG40
A	THR72
A	PHE227
A	VAL282
A	VAL284
A	LYS286
A	ILE289
A	HOH340

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site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE C2F B 314

Chain	Residue
B	THR19
B	TYR52
B	ASP53
B	LEU54
B	VAL121
B	GLY122
B	ALA123
B	ILE155
B	ARG158
B	LYS172
B	GLN183
B	LEU231
B	GLU280
B	HOH322
B	HOH325
B	HOH327

---

site_id	AC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE C2F B 315

Chain	Residue
B	THR19
B	PRO20
B	LYS22
B	LYS29
B	ILE33
B	LYS36
B	ARG40
B	ILE70
B	THR72
B	LYS223
B	PHE227
B	VAL282
B	VAL284
B	LYS286
B	HOH349
B	HOH358

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