Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005272 | molecular_function | sodium channel activity |
A | 0006814 | biological_process | sodium ion transport |
A | 0015280 | molecular_function | ligand-gated sodium channel activity |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 1 |
Chain | Residue |
A | LYS212 |
A | ARG310 |
A | GLU314 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CS A 467 |
Chain | Residue |
A | THR237 |
A | THR240 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CS A 468 |
Chain | Residue |
A | GLU299 |
A | TYR301 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CS A 469 |
Chain | Residue |
A | ASP433 |
A | CS470 |
A | CS470 |
A | CS470 |
A | ASP433 |
A | ASP433 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE CS A 470 |
Chain | Residue |
A | GLY432 |
A | GLY432 |
A | GLY432 |
A | ASP433 |
A | ASP433 |
A | ASP433 |
A | CS469 |
A | CS469 |
A | CS469 |
Functional Information from PROSITE/UniProt
site_id | PS01206 |
Number of Residues | 21 |
Details | ASC Amiloride-sensitive sodium channels signature. YsiTaCridCeTryLVenCnC |
Chain | Residue | Details |
A | TYR304-CYS324 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 23 |
Details | TRANSMEM: Helical |
Chain | Residue | Details |
A | TRP47-PHE70 | |
site_id | SWS_FT_FI2 |
Number of Residues | 355 |
Details | TOPO_DOM: Extracellular |
Chain | Residue | Details |
A | LEU71-GLU426 | |
site_id | SWS_FT_FI3 |
Number of Residues | 26 |
Details | TRANSMEM: Discontinuously helical |
Chain | Residue | Details |
A | VAL427-PHE453 | |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Important for channel gating |
Chain | Residue | Details |
A | TYR72 | |
A | TRP288 | |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | SITE: Important for channel desensitizing |
Chain | Residue | Details |
A | GLU80 | |
Chain | Residue | Details |
A | ASN367 | |
A | ASN394 | |