Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019538 | biological_process | protein metabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 459 |
| Chain | Residue |
| A | LEU152 |
| A | ILE153 |
| A | THR155 |
| A | LYS247 |
| A | MET250 |
| A | HOH476 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE LI A 460 |
| Chain | Residue |
| A | GLU310 |
| A | SO4461 |
| A | HOH489 |
| A | LYS226 |
| A | ASP231 |
| A | ASP249 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 461 |
| Chain | Residue |
| A | LYS226 |
| A | ASP308 |
| A | ALA309 |
| A | GLU310 |
| A | GLY311 |
| A | ARG312 |
| A | ARG341 |
| A | LI460 |
| A | HOH489 |
| A | HOH546 |
| A | HOH547 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 462 |
| Chain | Residue |
| A | GLY284 |
| A | GLY284 |
| A | GLY284 |
| A | SER285 |
| A | SER285 |
| A | SER285 |
| A | HOH482 |
| A | HOH482 |
| A | HOH482 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 463 |
| Chain | Residue |
| A | ARG312 |
| A | ARG341 |
| A | SER396 |
| A | SER397 |
| A | GLY403 |
| A | THR406 |
| A | HOH828 |
| A | HOH869 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 464 |
| Chain | Residue |
| A | LYS179 |
| A | LYS179 |
| A | LYS212 |
| A | ARG271 |
| A | PG4472 |
| A | HOH629 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 465 |
| Chain | Residue |
| A | LYS137 |
| A | ARG138 |
| A | GLN266 |
| A | HOH520 |
| A | HOH849 |
| A | HOH859 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 466 |
| Chain | Residue |
| A | ARG383 |
| A | HIS413 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 467 |
| Chain | Residue |
| A | SER123 |
| A | PRO124 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 468 |
| Chain | Residue |
| A | THR190 |
| A | GLU191 |
| A | THR296 |
| A | ARG299 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 469 |
| Chain | Residue |
| A | THR155 |
| A | MET160 |
| A | HOH585 |
| A | HOH739 |
| A | HOH741 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 470 |
| Chain | Residue |
| A | ALA298 |
| A | ARG299 |
| A | LYS300 |
| A | ASP392 |
| A | HIS413 |
| A | HOH808 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 471 |
| Chain | Residue |
| A | ALA60 |
| A | SER357 |
| A | TYR452 |
| A | HOH652 |
| A | HOH663 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 A 472 |
| Chain | Residue |
| A | GLU177 |
| A | LYS179 |
| A | LYS212 |
| A | TRP213 |
| A | GLY214 |
| A | ARG271 |
| A | SO4464 |
| site_id | BC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PG4 A 473 |
| Chain | Residue |
| A | ALA298 |
| A | ALA320 |
| A | GLN380 |
| A | ARG383 |
| A | GLN412 |
| A | HIS413 |
| A | PHE414 |
| A | VAL415 |
| A | SER416 |
| A | ASP417 |
| A | HOH667 |
| A | HOH763 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 A 474 |
| Chain | Residue |
| A | LEU378 |
| A | PHE379 |
| A | HOH515 |
| A | HOH775 |
| A | HOH875 |
| A | SER366 |
| A | ASP370 |
| A | PRO372 |
| A | LEU373 |
Functional Information from PROSITE/UniProt
| site_id | PS00631 |
| Number of Residues | 8 |
| Details | CYTOSOL_AP Cytosol aminopeptidase signature. NTDAEGRV |
| Chain | Residue | Details |
| A | ASN306-VAL313 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1lam |
| Chain | Residue | Details |
| A | ASP231 | |
| A | LYS238 | |
| A | ARG312 | |
