3IIX

X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with methionine and 5'deoxyadenosine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SF4 A 2460

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	GLY109
A	MET1401

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE MET A 1401

Chain	Residue
A	TYR303
A	HOH474
A	HOH480
A	HOH483
A	HOH493
A	5AD1501
A	SF42460
A	SER108
A	SER136
A	GLY138
A	ARG180

---

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 5AD A 1501

Chain	Residue
A	TYR69
A	GLN107
A	ARG159
A	GLU161
A	MET199
A	PRO229
A	ILE231
A	LEU305
A	TYR306
A	HOH480
A	HOH501
A	HOH587
A	MET1401

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE CPS A 1701

Chain	Residue
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	HOH392
A	HOH421
A	HOH477
A	HOH504
A	HOH512
A	HOH513
A	HOH663
A	HOH694
A	CPS1704
A	CPS1705

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CPS A 1702

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH362
A	HOH543
A	HOH577
A	HOH664
A	HOH721
A	HOH723
A	HOH792

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CPS A 1703

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	LEU250
A	HOH354
A	HOH403
A	HOH566
A	HOH570
A	HOH583
A	HOH809
A	CPS1704

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CPS A 1704

Chain	Residue
A	THR317
A	ALA318
A	HOH449
A	HOH466
A	HOH583
A	HOH731
A	HOH735
A	HOH759
A	CPS1701
A	CPS1703

---

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CPS A 1705

Chain	Residue
A	LYS128
A	MET324
A	LYS325
A	GLU328
A	HOH361
A	HOH457
A	HOH612
A	HOH694
A	HOH705
A	HOH804
A	CPS1701

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE H2S A 1801

Chain	Residue
A	CYS319

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE H2S A 1802

Chain	Residue
A	CYS319
A	HOH538

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE H2S A 1803

Chain	Residue
A	CYS319
A	CSO322
A	ARG279

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 351

Chain	Residue
A	THR268
A	ALA270
A	TYR306
A	HOH572
A	HOH587

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CO3 A 352

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE HOH A 353

Chain	Residue
A	ARG159
A	PRO266
A	MET291
A	HOH544
A	HOH714
A	HOH752

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE HOH A 354

Chain	Residue
A	PHE246
A	HOH460
A	HOH529
A	HOH687
A	CPS1703

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---