3IIX
X-ray structure of the FeFe-hydrogenase maturase HydE from T. maritima in complex with methionine and 5'deoxyadenosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018130 | biological_process | obsolete heterocycle biosynthetic process |
| A | 0042364 | biological_process | water-soluble vitamin biosynthetic process |
| A | 0044271 | biological_process | obsolete cellular nitrogen compound biosynthetic process |
| A | 0044272 | biological_process | sulfur compound biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 1901362 | biological_process | obsolete organic cyclic compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SF4 A 2460 |
| Chain | Residue |
| A | CYS63 |
| A | CYS67 |
| A | CYS70 |
| A | GLY109 |
| A | MET1401 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MET A 1401 |
| Chain | Residue |
| A | TYR303 |
| A | HOH474 |
| A | HOH480 |
| A | HOH483 |
| A | HOH493 |
| A | 5AD1501 |
| A | SF42460 |
| A | SER108 |
| A | SER136 |
| A | GLY138 |
| A | ARG180 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 5AD A 1501 |
| Chain | Residue |
| A | TYR69 |
| A | GLN107 |
| A | ARG159 |
| A | GLU161 |
| A | MET199 |
| A | PRO229 |
| A | ILE231 |
| A | LEU305 |
| A | TYR306 |
| A | HOH480 |
| A | HOH501 |
| A | HOH587 |
| A | MET1401 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CPS A 1701 |
| Chain | Residue |
| A | GLN98 |
| A | PHE99 |
| A | GLY100 |
| A | PRO276 |
| A | GLY277 |
| A | GLU280 |
| A | ARG284 |
| A | MET324 |
| A | LEU330 |
| A | HOH392 |
| A | HOH421 |
| A | HOH477 |
| A | HOH504 |
| A | HOH512 |
| A | HOH513 |
| A | HOH663 |
| A | HOH694 |
| A | CPS1704 |
| A | CPS1705 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CPS A 1702 |
| Chain | Residue |
| A | LYS37 |
| A | ASP40 |
| A | LYS170 |
| A | ARG284 |
| A | SER297 |
| A | LYS315 |
| A | ASP316 |
| A | THR317 |
| A | HOH362 |
| A | HOH543 |
| A | HOH577 |
| A | HOH664 |
| A | HOH721 |
| A | HOH723 |
| A | HOH792 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CPS A 1703 |
| Chain | Residue |
| A | ARG29 |
| A | GLU33 |
| A | THR247 |
| A | LEU250 |
| A | HOH354 |
| A | HOH403 |
| A | HOH566 |
| A | HOH570 |
| A | HOH583 |
| A | HOH809 |
| A | CPS1704 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CPS A 1704 |
| Chain | Residue |
| A | THR317 |
| A | ALA318 |
| A | HOH449 |
| A | HOH466 |
| A | HOH583 |
| A | HOH731 |
| A | HOH735 |
| A | HOH759 |
| A | CPS1701 |
| A | CPS1703 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CPS A 1705 |
| Chain | Residue |
| A | LYS128 |
| A | MET324 |
| A | LYS325 |
| A | GLU328 |
| A | HOH361 |
| A | HOH457 |
| A | HOH612 |
| A | HOH694 |
| A | HOH705 |
| A | HOH804 |
| A | CPS1701 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE H2S A 1801 |
| Chain | Residue |
| A | CYS319 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE H2S A 1802 |
| Chain | Residue |
| A | CYS319 |
| A | HOH538 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE H2S A 1803 |
| Chain | Residue |
| A | CYS319 |
| A | CSO322 |
| A | ARG279 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 351 |
| Chain | Residue |
| A | THR268 |
| A | ALA270 |
| A | TYR306 |
| A | HOH572 |
| A | HOH587 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CO3 A 352 |
| Chain | Residue |
| A | ARG54 |
| A | THR134 |
| A | ARG155 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HOH A 353 |
| Chain | Residue |
| A | ARG159 |
| A | PRO266 |
| A | MET291 |
| A | HOH544 |
| A | HOH714 |
| A | HOH752 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HOH A 354 |
| Chain | Residue |
| A | PHE246 |
| A | HOH460 |
| A | HOH529 |
| A | HOH687 |
| A | CPS1703 |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG |
| Chain | Residue | Details |
| A | VAL323-GLY340 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS67 | |
| A | CYS70 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | CSS311 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | CYS319 | |
| A | CSO322 |
