3IIP

Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	histidine biosynthetic process
A	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
B	0000105	biological_process	histidine biosynthetic process
B	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
C	0000105	biological_process	histidine biosynthetic process
C	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
D	0000105	biological_process	histidine biosynthetic process
D	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
E	0000105	biological_process	histidine biosynthetic process
E	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity
F	0000105	biological_process	histidine biosynthetic process
F	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 15P A 256

Chain	Residue
A	ALA117
A	GLY121
A	SER122
D	ALA117
D	SER122

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 15P B 256

Chain	Residue
B	HOH269
C	SER122
B	ALA117
B	GLY121
B	SER122
B	GLU161

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 15P E 256

Chain	Residue
E	ALA117
E	SER122
E	GLU161
F	GLY121
F	SER122
F	HOH275

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