3IEB
Crystal structure of 3-keto-L-gulonate-6-phosphate decarboxylase from Vibrio cholerae O1 biovar El Tor str. N16961
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019854 | biological_process | L-ascorbic acid catabolic process |
| A | 0033982 | molecular_function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019854 | biological_process | L-ascorbic acid catabolic process |
| B | 0033982 | molecular_function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| C | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019854 | biological_process | L-ascorbic acid catabolic process |
| C | 0033982 | molecular_function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| D | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019854 | biological_process | L-ascorbic acid catabolic process |
| D | 0033982 | molecular_function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| E | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019854 | biological_process | L-ascorbic acid catabolic process |
| E | 0033982 | molecular_function | 3-dehydro-L-gulonate-6-phosphate decarboxylase activity |
| E | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ASP67 |
| B | ARG139 |
| A | GLY68 |
| A | GLY69 |
| A | ALA70 |
| A | THR94 |
| A | ALA97 |
| A | HOH223 |
| A | HOH544 |
| A | HOH547 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2001 |
| Chain | Residue |
| A | ALA88 |
| A | ALA90 |
| A | HIS91 |
| A | ILE92 |
| A | ILE95 |
| A | TRP125 |
| A | HOH625 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 216 |
| Chain | Residue |
| A | ALA26 |
| A | ASN53 |
| A | HIS54 |
| A | PRO55 |
| A | ASN56 |
| A | HIS57 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 217 |
| Chain | Residue |
| A | GLY170 |
| A | GLY171 |
| A | HOH633 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| B | HIS54 |
| B | PRO55 |
| B | ASN56 |
| B | HIS57 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 2001 |
| Chain | Residue |
| B | GLN12 |
| B | THR13 |
| B | ARG192 |
| B | HOH373 |
| B | HOH634 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 2002 |
| Chain | Residue |
| B | ALA88 |
| B | ALA90 |
| B | HIS91 |
| B | ILE92 |
| B | ASP121 |
| B | TRP125 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 2003 |
| Chain | Residue |
| B | ILE113 |
| B | TRP117 |
| B | TYR135 |
| B | HIS136 |
| B | ARG137 |
| B | HOH472 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 216 |
| Chain | Residue |
| A | ARG139 |
| B | ASP67 |
| B | GLY68 |
| B | GLY69 |
| B | ALA70 |
| B | THR94 |
| B | ALA97 |
| B | HOH649 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 217 |
| Chain | Residue |
| B | GLY170 |
| B | GLY171 |
| B | ALA190 |
| B | GLY191 |
| B | HOH223 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 2001 |
| Chain | Residue |
| C | ALA88 |
| C | ALA90 |
| C | HIS91 |
| C | ILE92 |
| C | TRP125 |
| C | HOH287 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 2002 |
| Chain | Residue |
| C | ILE113 |
| C | TYR135 |
| C | HIS136 |
| C | SER138 |
| C | HOH246 |
| C | HOH482 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 216 |
| Chain | Residue |
| C | HIS54 |
| C | PRO55 |
| C | ASN56 |
| C | HIS57 |
| C | HOH688 |
| C | HOH689 |
| site_id | BC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 C 217 |
| Chain | Residue |
| C | ASP67 |
| C | GLY68 |
| C | GLY69 |
| C | ALA70 |
| C | ALA93 |
| C | THR94 |
| C | ALA97 |
| C | HOH271 |
| C | HOH390 |
| C | HOH523 |
| E | ARG139 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 218 |
| Chain | Residue |
| C | GLY170 |
| C | GLY171 |
| C | GLY191 |
| C | HOH228 |
| C | HOH303 |
| C | HOH467 |
| C | HOH681 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 219 |
| Chain | Residue |
| C | ARG192 |
| C | HOH288 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 2001 |
| Chain | Residue |
| D | ASN56 |
| D | HIS57 |
| D | ASP82 |
| D | ARG51 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D 2003 |
| Chain | Residue |
| D | ALA88 |
| D | ALA89 |
| D | ALA90 |
| D | ILE95 |
| D | TRP125 |
| D | HOH587 |
| D | HOH760 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 216 |
| Chain | Residue |
| D | GLY191 |
| D | ARG192 |
| D | HOH301 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 217 |
| Chain | Residue |
| B | ARG192 |
| D | HIS54 |
| D | PRO55 |
| D | ASN56 |
| D | HIS57 |
| D | HOH524 |
| D | HOH616 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 218 |
| Chain | Residue |
| D | ASP67 |
| D | GLY68 |
| D | GLY69 |
| D | ALA70 |
| D | THR94 |
| D | ALA97 |
| D | ARG139 |
| D | HOH260 |
| D | HOH615 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 219 |
| Chain | Residue |
| D | GLY170 |
| D | GLY171 |
| D | HOH286 |
| D | HOH540 |
| D | HOH541 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL E 2001 |
| Chain | Residue |
| E | ALA88 |
| E | ALA90 |
| E | HIS91 |
| E | ILE92 |
| E | ILE95 |
| E | ASP121 |
| E | TRP125 |
| E | HOH260 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 2002 |
| Chain | Residue |
| E | ILE113 |
| E | TRP117 |
| E | TYR135 |
| E | HIS136 |
| E | HOH229 |
| E | HOH282 |
| site_id | CC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 E 216 |
| Chain | Residue |
| C | ARG139 |
| E | ASP67 |
| E | GLY68 |
| E | GLY69 |
| E | ALA70 |
| E | THR94 |
| E | ALA97 |
| E | HOH233 |
| E | HOH488 |
| E | HOH617 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 E 217 |
| Chain | Residue |
| A | ARG192 |
| E | ASN53 |
| E | HIS54 |
| E | PRO55 |
| E | ASN56 |
| E | HIS57 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 E 218 |
| Chain | Residue |
| E | GLY170 |
| E | GLY171 |
| E | ALA190 |
| E | GLY191 |
| E | HOH423 |
| E | HOH442 |
| E | HOH458 |
| E | HOH608 |
| E | HOH721 |
