Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3ID0

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium

Functional Information from GO Data
ChainGOidnamespacecontents
A0004161molecular_functiondimethylallyltranstransferase activity
A0004337molecular_function(2E,6E)-farnesyl diphosphate synthase activity
A0004659molecular_functionprenyltransferase activity
A0005737cellular_componentcytoplasm
A0008299biological_processisoprenoid biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0045337biological_processfarnesyl diphosphate biosynthetic process
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE NI9 A 363
ChainResidue
ATYR94
ALYS264
AMG401
AMG402
AMG403
AASP98
AASP102
AARG107
AGLN167
ALYS207
ATHR208
AGLN247
AASP250

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 401
ChainResidue
AASP98
AASP102
ANI9363

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 402
ChainResidue
AASP250
AASP251
AASP268
ANI9363

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 403
ChainResidue
AASP98
AASP102
AASP170
ANI9363

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 405
ChainResidue
ALYS25
AHIS141
ALYS158

site_idAC6
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 A 406
ChainResidue
AGLY47
ALYS48
ATYR49
APHE50
AARG51
AGLN91
AARG108
AHOH364
AHOH365
AHOH396

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. IGeyFQVqDDVmD
ChainResidueDetails
AILE242-ASP254

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DgsvmRRG
ChainResidueDetails
ALEU95-GLY109

237735

PDB entries from 2025-06-18

PDB statisticsPDBj update infoContact PDBjnumon