3IBC
Crystal Structure of Caspase-7 incomplex with Acetyl-YVAD-CHO
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
D | 0006508 | biological_process | proteolysis |
D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | SITE: Involved in allosteric regulation => ECO:0000269|PubMed:15314233, ECO:0000269|PubMed:19581639 |
Chain | Residue | Details |
B | TYR223 | |
D | TYR523 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: (Microbial infection) ADP-riboxanated arginine => ECO:0000269|PubMed:35338844, ECO:0000269|PubMed:35446120 |
Chain | Residue | Details |
B | ARG233 | |
D | ARG533 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine; by PAK2 => ECO:0000269|PubMed:21555521, ECO:0000269|PubMed:27889207 |
Chain | Residue | Details |
B | SER239 | |
D | SER539 | |
A | SER47 | |
C | PHE336 | |
C | MET345 | |
C | SER347 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Involved in allosteric regulation => ECO:0000269|PubMed:15314233, ECO:0000269|PubMed:19581639 |
Chain | Residue | Details |
A | ARG187 | |
C | ARG487 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine; by PAK2 => ECO:0000269|PubMed:21555521, ECO:0000269|PubMed:27889207 |
Chain | Residue | Details |
A | SER30 | |
C | SER330 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER37 | |
C | SER337 |
site_id | SWS_FT_FI7 |
Number of Residues | 2 |
Details | MOD_RES: Phosphothreonine; by PAK2 => ECO:0000269|PubMed:21555521, ECO:0000269|PubMed:27889207 |
Chain | Residue | Details |
A | THR173 | |
C | THR473 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qx3 |
Chain | Residue | Details |
A | CYS186 | |
A | GLY145 | |
A | HIS144 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qx3 |
Chain | Residue | Details |
C | GLY445 | |
C | HIS444 | |
C | CYS486 |